metronidazole has been researched along with Autoimmune Diabetes in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight children with type 1 diabetes and H." | 2.70 | Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study. ( Bégué, RE; Compton, T; Gómez, R; Vargas, A, 2002) |
| "Although giardiasis is rare, its histopathological and serological picture may resemble that of CD." | 1.38 | Celiac disease and giardiasis: a case report. ( Bohr, J; Edling, L; Eriksson, S; Rathsman, S, 2012) |
| "The study included 100 youth with type 1 diabetes and seropositive for Hp (European Caucasians: n=49; Moghrabin Caucasians: n=51)." | 1.34 | [Helicobacter pylori infection and eradication are not related to glycosylated hemoglobin levels (HbA1c) in young patients with type 1 diabetes]. ( Dorchy, H; Khalil, T; Melot, C; Scaillon, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alidjinou, EK | 1 |
| Bonnet, I | 1 |
| Canis, F | 1 |
| Dewulf, G | 1 |
| Mazars, E | 1 |
| Cattoen, C | 1 |
| Cesario, V | 1 |
| Di Rienzo, TA | 1 |
| Campanale, M | 1 |
| D'angelo, G | 1 |
| Barbaro, F | 1 |
| Gigante, G | 1 |
| Vitale, G | 1 |
| Scavone, G | 1 |
| Pitocco, D | 1 |
| Gasbarrini, A | 1 |
| Ojetti, V | 1 |
| Batista, N | 1 |
| Fernández, MP | 1 |
| Gambra, ML | 1 |
| Rodríguez, L | 1 |
| Edling, L | 1 |
| Rathsman, S | 1 |
| Eriksson, S | 1 |
| Bohr, J | 1 |
| Bégué, RE | 1 |
| Gómez, R | 1 |
| Compton, T | 1 |
| Vargas, A | 1 |
| Khalil, T | 1 |
| Dorchy, H | 1 |
| Scaillon, M | 1 |
| Melot, C | 1 |
| Rouquette-Vincenti, I | 1 |
| Petitjeans, F | 1 |
| Villevieille, T | 1 |
| Szymczyszyn, P | 1 |
| Fangio, P | 1 |
| Baranger, B | 1 |
| Brinquin, L | 1 |
| Kappel, J | 1 |
| Calissi, P | 1 |
| Duran, D | 1 |
| Lagarrigue, J | 1 |
| Blazy-Maugen, F | 1 |
| Michel, G | 1 |
| Ziane, M | 1 |
| Bouziane, M | 1 |
1 review available for metronidazole and Autoimmune Diabetes
| Article | Year |
|---|---|
Nephrology: 3. Safe drug prescribing for patients with renal insufficiency.
Topics: Adult; Anti-Infective Agents; Biological Availability; Creatinine; Diabetes Mellitus, Type 1; Drug A | 2002 |
1 trial available for metronidazole and Autoimmune Diabetes
| Article | Year |
|---|---|
Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study.
Topics: Adolescent; Anti-Bacterial Agents; Child; Clarithromycin; Diabetes Mellitus, Type 1; Female; Follow- | 2002 |
7 other studies available for metronidazole and Autoimmune Diabetes
| Article | Year |
|---|---|
[Gardnerella vaginalis bacteremia in a male patient].
Topics: Adenocarcinoma; Amikacin; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bac | 2013 |
Methane intestinal production and poor metabolic control in type I diabetes complicated by autonomic neuropathy.
Topics: Adult; Anti-Bacterial Agents; Bacteria, Anaerobic; Breath Tests; Diabetes Mellitus, Type 1; Diabetic | 2014 |
[Fournier's gangrene caused by Streptococcus agalactiae in a non-pregnant woman].
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Combined Modality Therapy; Debridement; Diabetes Mellitus | 2009 |
Celiac disease and giardiasis: a case report.
Topics: Adult; Antibodies, Anti-Idiotypic; Biopsy; Celiac Disease; Diabetes Mellitus, Type 1; Diagnosis, Dif | 2012 |
[Helicobacter pylori infection and eradication are not related to glycosylated hemoglobin levels (HbA1c) in young patients with type 1 diabetes].
Topics: Adolescent; Adult; Age Factors; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulce | 2007 |
[Obesity, diabetes mellitus, and gas gangrene: a major therapeutic challenge].
Topics: Abscess; Amikacin; Anus Diseases; Buttocks; Candidiasis; Ceftazidime; Colostomy; Combined Modality T | 2001 |
[Peripheral concentrations and distribution of a combination of anti-infective agents (spiramycin-metronidazole) in diabetics].
Topics: Anti-Infective Agents; Dentistry, Operative; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; D | 1985 |