Page last updated: 2024-10-31

metronidazole and Aura

metronidazole has been researched along with Aura in 3 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schattner, A1
Adi, M1
Karpova, MN1
Karganov, MY1
Klishina, NY1
Khlebnikova, NN1
Kryzhanovskii, GN1
Wienbren, M1
Perinpanayagam, RM1
Camba, L1
Lee, CA1

Other Studies

3 other studies available for metronidazole and Aura

ArticleYear
All in his head: an unexpected space-occupying lesion.
    The American journal of medicine, 2014, Volume: 127, Issue:2

    Topics: Aged; Anti-Infective Agents; Anticonvulsants; Brain Abscess; Ceftriaxone; Craniotomy; Drainage; Epil

2014
Contribution of protein synthesis to mechanisms of antiepileptic system activity in kindling.
    Bulletin of experimental biology and medicine, 2002, Volume: 133, Issue:6

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Epilepsy; Kindling, Neurologic; Metronidazole; Mic

2002
Convulsions and encephalopathy in a patient with leukemia after treatment with metronidazole.
    Journal of clinical pathology, 1985, Volume: 38, Issue:9

    Topics: Adult; Brain Diseases; Epilepsy; Female; Humans; Leukemia, Myeloid, Acute; Metronidazole

1985