metronidazole has been researched along with Atopic Hypersensitivity in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of immediate rhinoconjunctivitis induced by both metamizole and metronidazole." | 7.69 | Immediate rhinoconjunctivitis induced by metamizole and metronidazole. ( Añíbarro, B; Fontela, JL, 1997) |
| "To report a case of immediate rhinoconjunctivitis induced by both metamizole and metronidazole." | 3.69 | Immediate rhinoconjunctivitis induced by metamizole and metronidazole. ( Añíbarro, B; Fontela, JL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beyaz, Ş | 1 |
| Akdeniz, N | 1 |
| Yılmaz, A | 1 |
| Demir, S | 1 |
| Öztop, N | 1 |
| Çolakoğlu, B | 1 |
| Büyüköztürk, S | 1 |
| Deniz, G | 1 |
| Gelincik, A | 1 |
| Backus, KV | 1 |
| Muzny, CA | 1 |
| Beauchamps, LS | 1 |
| Seto, K | 1 |
| Knowles, SR | 1 |
| Weber, EA | 1 |
| Añíbarro, B | 1 |
| Fontela, JL | 1 |
1 trial available for metronidazole and Atopic Hypersensitivity
| Article | Year |
|---|---|
Diagnostic workup including CD203c-based basophil activation test in immediate hypersensitivity due to metronidazole and ornidazole and evaluation of cross-reactivity in between.
Topics: Basophil Degranulation Test; Basophils; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; | 2021 |
3 other studies available for metronidazole and Atopic Hypersensitivity
| Article | Year |
|---|---|
Trichomonas vaginalis Treated With Boric Acid in a Metronidazole Allergic Female.
Topics: Aged; Antiprotozoal Agents; Boric Acids; Drug Hypersensitivity; Drug-Related Side Effects and Advers | 2017 |
Immediate hypersensitivity reaction induced by metronidazole.
Topics: Aged; Anti-Infective Agents; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immediate; Met | 2012 |
Immediate rhinoconjunctivitis induced by metamizole and metronidazole.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antitrichomonal Agents; Conjunctivitis; Dipyrone; Fe | 1997 |