metronidazole has been researched along with Asymptomatic Conditions in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "About half of patients with Crohn's disease (CD) require surgery within 10 years of diagnosis." | 2.66 | Colonoscopy-guided therapy for the prevention of post-operative recurrence of Crohn's disease. ( Bravo-Soto, GA; Candia, R; Hernandez, C; Monrroy, H; Nguyen, GC, 2020) |
| "Giardiasis is an important cause of waterborne and foodborne diarrhea, daycare center outbreaks, and traveler's diarrhea." | 2.61 | Giardiasis: An Overview. ( Kam, JKM; Leung, AAM; Leung, AKC; Sergi, CM; Wong, AHC, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Candia, R | 1 |
| Bravo-Soto, GA | 1 |
| Monrroy, H | 1 |
| Hernandez, C | 1 |
| Nguyen, GC | 1 |
| Okamoto, K | 1 |
| Watanabe, T | 1 |
| Komeda, Y | 1 |
| Okamoto, A | 1 |
| Minaga, K | 1 |
| Kamata, K | 1 |
| Yamao, K | 1 |
| Takenaka, M | 1 |
| Hagiwara, S | 1 |
| Sakurai, T | 1 |
| Tanaka, T | 1 |
| Sakamoto, H | 1 |
| Fujimoto, K | 1 |
| Nishida, N | 1 |
| Kudo, M | 1 |
| Calaway, AC | 1 |
| Jacob, JM | 1 |
| Tong, Y | 1 |
| Shumaker, L | 1 |
| Kitley, W | 1 |
| Boris, RS | 1 |
| Cary, C | 1 |
| Kaimakliotis, H | 1 |
| Masterson, TA | 1 |
| Bihrle, R | 1 |
| Koch, MO | 1 |
| Leung, AKC | 1 |
| Leung, AAM | 1 |
| Wong, AHC | 1 |
| Sergi, CM | 1 |
| Kam, JKM | 1 |
| Debnath, A | 1 |
| Rodriguez, MA | 1 |
| Ankri, S | 1 |
| Nagel, R | 1 |
| Cuttell, L | 1 |
| Stensvold, CR | 1 |
| Mills, PC | 1 |
| Bielefeldt-Ohmann, H | 1 |
| Traub, RJ | 1 |
2 reviews available for metronidazole and Asymptomatic Conditions
| Article | Year |
|---|---|
Colonoscopy-guided therapy for the prevention of post-operative recurrence of Crohn's disease.
Topics: Adalimumab; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asymptomatic Dise | 2020 |
Giardiasis: An Overview.
Topics: Animals; Asymptomatic Diseases; Child; Clinical Trials as Topic; Diarrhea; Giardia; Giardiasis; Huma | 2019 |
1 trial available for metronidazole and Asymptomatic Conditions
| Article | Year |
|---|---|
A Prospective Program to Reduce the Clinical Incidence of Clostridium difficile Colitis Infection after Cystectomy.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Asymptomatic Diseases; Clostridioides difficile | 2019 |
3 other studies available for metronidazole and Asymptomatic Conditions
| Article | Year |
|---|---|
Dysbiosis-Associated Polyposis of the Colon-Cap Polyposis.
Topics: Ampicillin; Anti-Bacterial Agents; Asymptomatic Diseases; Bacteria; Colon; Colonic Polyps; Dysbiosis | 2018 |
Editorial: Recent Progresses in Amebiasis.
Topics: Amebicides; Anisomycin; Asymptomatic Diseases; Drug Discovery; Dysentery, Amebic; Entamoeba histolyt | 2019 |
Blastocystis subtypes in symptomatic and asymptomatic family members and pets and response to therapy.
Topics: Adult; Aged; Animals; Antiprotozoal Agents; Asymptomatic Diseases; Biopsy; Blastocystis; Blastocysti | 2012 |