metronidazole has been researched along with Asymptomatic Colonization in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We measured biomarkers of subclinical vaginal inflammation, endogenous antimicrobial activity, and vaginal flora in women with BV and repeated sampling 1 week and 1 month after completion of metronidazole therapy." | 3.81 | Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity. ( Anderson, S; Chandra, N; Cunningham, TD; Dawood, HY; Doncel, G; Fashemi, T; Fichorova, RN; Herold, B; Kimble, T; Mesquita, PM; Rabe, L; Schwartz, J; Thurman, AR, 2015) |
| "Accuracy of screening tests for bacterial vaginosis varies." | 2.66 | Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Berkman, N; Clark, R; Kahwati, LC; Patel, SV; Urrutia, R; Viswanathan, M; Zeng, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahwati, LC | 1 |
| Clark, R | 1 |
| Berkman, N | 1 |
| Urrutia, R | 1 |
| Patel, SV | 1 |
| Zeng, J | 1 |
| Viswanathan, M | 1 |
| Coudray, MS | 1 |
| Sheehan, DM | 1 |
| Li, T | 1 |
| Cook, RL | 1 |
| Schwebke, J | 1 |
| Madhivanan, P | 1 |
| Thurman, AR | 1 |
| Kimble, T | 1 |
| Herold, B | 1 |
| Mesquita, PM | 1 |
| Fichorova, RN | 1 |
| Dawood, HY | 1 |
| Fashemi, T | 1 |
| Chandra, N | 1 |
| Rabe, L | 1 |
| Cunningham, TD | 1 |
| Anderson, S | 1 |
| Schwartz, J | 1 |
| Doncel, G | 1 |
| Salvador, F | 1 |
| Sulleiro, E | 1 |
| Sánchez-Montalvá, A | 1 |
| Alonso, C | 1 |
| Santos, J | 1 |
| Fuentes, I | 1 |
| Molina, I | 1 |
1 review available for metronidazole and Asymptomatic Colonization
| Article | Year |
|---|---|
Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Topics: Anti-Bacterial Agents; Asymptomatic Infections; Clindamycin; Female; Humans; Mass Screening; Metroni | 2020 |
3 other studies available for metronidazole and Asymptomatic Colonization
| Article | Year |
|---|---|
Factors Associated With the Recurrence, Persistence, and Clearance of Asymptomatic Bacterial Vaginosis Among Young African American Women: A Repeated-Measures Latent Class Analysis.
Topics: Adult; Asymptomatic Infections; Black or African American; Female; Humans; Incidence; Latent Class A | 2020 |
Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity.
Topics: Adult; Anti-Infective Agents; Asymptomatic Infections; Biomarkers; Biopsy; Cervix Uteri; Female; Hum | 2015 |
Epidemiological and clinical profile of adult patients with Blastocystis sp. infection in Barcelona, Spain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiprotozoal Agents; Asymptomatic Infections; Blastocys | 2016 |