metronidazole has been researched along with Asthma in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Afebrile seizures associated with rotavirus gastroenteritis, respiratory syncytial virus bronchiolitis, influenza infection, asthma, blood transfusions, and intake of a number of drugs (including theophylline, cephalosporins, metronidazole, and acyclovir) with therapeutic drug levels are uncommonly encountered in clinical practice." | 4.85 | Common causes of uncommon seizures. ( Boustany, RM; El-Bitar, MK, 2009) |
| "Perturbation of commensal bacteria by antibiotic exposure aggravates ovalbumin (OVA)-induced allergic asthma in pre-weaning mice." | 3.88 | Commensal bacteria aggravate allergic asthma via NLRP3/IL-1β signaling in post-weaning mice. ( Chen, Y; Huang, C; Sun, R; Tian, Z; Wang, J; Wei, H; Zheng, X; Zhou, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, C | 1 |
| Wang, J | 1 |
| Zheng, X | 1 |
| Chen, Y | 1 |
| Zhou, R | 1 |
| Wei, H | 1 |
| Sun, R | 1 |
| Tian, Z | 1 |
| El-Bitar, MK | 1 |
| Boustany, RM | 1 |
| Kumar, P | 1 |
| Parashette, KR | 1 |
| Noronha, P | 1 |
| Selgrad, M | 1 |
| Bornschein, J | 1 |
| Malfertheiner, P | 1 |
| Barbato, A | 1 |
| Panizzolo, C | 1 |
| Landi, L | 1 |
| Semenzato, R | 1 |
| Rugge, M | 1 |
2 reviews available for metronidazole and Asthma
| Article | Year |
|---|---|
Common causes of uncommon seizures.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antiviral Agents; Asthma; Brain; Bronchiolitis; Child; | 2009 |
[Helicobacter pylori: an infection with local complications and systemic effects].
Topics: Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Asthma; Clarithromycin; Cross-Sectional | 2011 |
3 other studies available for metronidazole and Asthma
| Article | Year |
|---|---|
Commensal bacteria aggravate allergic asthma via NLRP3/IL-1β signaling in post-weaning mice.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Asthma; Bronchoalveolar Lavage Fluid; Disease Mode | 2018 |
Letter: Perioral dermatitis in a child associated with an inhalation steroid.
Topics: Administration, Inhalation; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cl | 2010 |
Asthma-like syndrome in a teenager.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Albuterol; Amoxicillin; Androstadienes; Anti-Ba | 2003 |