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metronidazole and Aspiculariasis

metronidazole has been researched along with Aspiculariasis in 9 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Botero, D1
Seth, D1
Lovekar, CD1
Schneider, GT1
Geary, WL1
Marks, MI1
Shapera, RM1
Brazeau, M1
Lelong, M1
Deroubaix, P1
Derambure, S1
Sorez, JP1
Vanlaeys, R1
Thelliez, P1
Hogedez, G1
Schreiber, W1
Pasricha, JS1
Pasricha, A1
Prakash, OM1
Lucian, O1
Lucian, M1
Calomfiresco, A1
Teodorof, A1
Găină, D1
Knosala, P1

Reviews

1 review available for metronidazole and Aspiculariasis

ArticleYear
Chemotherapy of human intestinal parasitic diseases.
    Annual review of pharmacology and toxicology, 1978, Volume: 18

    Topics: Amebiasis; Amides; Ancylostomiasis; Ascariasis; Bephenium Compounds; Cestode Infections; Emetine; Fu

1978

Other Studies

8 other studies available for metronidazole and Aspiculariasis

ArticleYear
Letter: A new chemotherapeutic property of metronidazole: effect against oxyurids in mice.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:12

    Topics: Animals; Metronidazole; Mice; Nematode Infections; Oxyuriasis

1973
Vaginitis in adolescent girls.
    Clinical obstetrics and gynecology, 1971, Volume: 14, Issue:4

    Topics: Adolescent; Boric Acids; Candida; Candidiasis, Vulvovaginal; Child; Enterobius; Female; Foreign Bodi

1971
Pediatric antimicrobial therapy. VI.
    Canadian Medical Association journal, 1973, Sep-15, Volume: 109, Issue:6

    Topics: Anti-Infective Agents; Ascariasis; Diphyllobothriasis; Giardiasis; Humans; Metronidazole; Niclosamid

1973
[Intestinal parasitoses in a general hospital pediatric department of (statistics for 12 years)].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1973, Volume: 18, Issue:4

    Topics: Adolescent; Age Factors; Ascariasis; Child; Child, Preschool; Female; France; Giardiasis; Humans; In

1973
[Parasitoses of the intestinal tract].
    Fortschritte der Medizin, 1974, Mar-14, Volume: 92, Issue:8

    Topics: Bephenium Compounds; Diagnosis, Differential; Eosinophilia; Giardiasis; Humans; Intestinal Diseases,

1974
Role of gastro-intestinal parasites in urticaria.
    Annals of allergy, 1972, Volume: 30, Issue:6

    Topics: Ascariasis; Bephenium Compounds; Dysentery, Amebic; Enterobius; Eukaryota; Feces; Giardiasis; Hookwo

1972
[Current possibilities concerning the prophylaxis and the fight against intestinal parasitoses in closed collective of children].
    Archives roumaines de pathologie experimentales et de microbiologie, 1967, Volume: 26, Issue:1

    Topics: Ascariasis; Child, Institutionalized; Feces; Giardiasis; Humans; Intestinal Diseases, Parasitic; Met

1967
[Results of control of parasites of the alimentary tract in closed environment].
    Wiadomosci parazytologiczne, 1968, Volume: 14, Issue:1

    Topics: Adolescent; Ascariasis; Child; Child, Preschool; Feces; Giardiasis; Helminthiasis; Humans; Metronida

1968