metronidazole has been researched along with Ascites in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Ascites: Accumulation or retention of free fluid within the peritoneal cavity.
Excerpt | Relevance | Reference |
---|---|---|
"Although it is rare, acute pancreatitis must be considered when evaluating patients presenting with abdominal pain and/or ascites in the postpartum period." | 1.33 | Ascites in the puerperium: a missed diagnosis of acute postpartum pancreatitis. ( Fakokunde, A; Gyang, A; Kalu, E; Whitlow, B, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (16.67) | 18.7374 |
1990's | 3 (50.00) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ugianskiene, A | 1 |
Gyang, A | 1 |
Kalu, E | 1 |
Fakokunde, A | 1 |
Whitlow, B | 1 |
Schölmerich, J | 1 |
Glück, T | 1 |
Gerding, DN | 1 |
Kromhout, JP | 1 |
Sullivan, JJ | 1 |
Hall, WH | 1 |
Hammond, TL | 1 |
Hankins, GD | 1 |
Snyder, RR | 1 |
de Leeuw, P | 1 |
de Mot, H | 1 |
Dugernier, T | 1 |
Wautelet, J | 1 |
Bohy, E | 1 |
Delmée, M | 1 |
1 review available for metronidazole and Ascites
Article | Year |
---|---|
[Spontaneous bacterial peritonitis].
Topics: Animals; Ascites; Bacterial Infections; Bacterial Translocation; Cefotaxime; Diagnosis, Differential | 1998 |
5 other studies available for metronidazole and Ascites
Article | Year |
---|---|
[Chlamydial infection with marked ascites that simulated ovarian cancer].
Topics: Anti-Bacterial Agents; Ascites; Chlamydia Infections; Chlamydia trachomatis; Diagnosis, Differential | 2013 |
Ascites in the puerperium: a missed diagnosis of acute postpartum pancreatitis.
Topics: Abdominal Pain; Acute Disease; Adult; Anti-Infective Agents; Ascites; Clarithromycin; Diagnosis, Dif | 2005 |
Antibiotic penetrance of ascitic fluid in dogs.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Ascites; Ascitic Fluid; Cephalosporins; Clindamycin | 1976 |
Transvaginal-peritoneal migration of Trichomonas vaginalis as a cause of ascites. A report of two cases.
Topics: Animals; Ascites; Female; Humans; Metronidazole; Pelvic Inflammatory Disease; Trichomonas vaginalis; | 1990 |
Primary infection of ascitic fluid with Clostridium difficile.
Topics: Ascites; Clostridium; Clostridium Infections; Duodenal Ulcer; Female; Gastrointestinal Hemorrhage; H | 1990 |