metronidazole has been researched along with Arthritis in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Arthritis: Acute or chronic inflammation of JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with Crohn's disease (C." | 1.26 | Therapy of Crohn's disease with metronidazole -- an uncontrolled trial --. ( Kasper, H; Kühn, HA; Sommer, H, 1979) |
| "Pneumatosis cystoides intestinalis was a sequal in two patients." | 1.26 | Bypass enteropathy: an inflammatory process in the excluded segment with systemic complications. ( Ament, ME; Drenick, EJ; Finegold, SM; Passaro, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, KS | 1 |
| Ray, LI | 1 |
| Giles, HW | 1 |
| Nowicki, MJ | 1 |
| NENNSTIEL, HJ | 1 |
| WALTHER, H | 1 |
| Schapira, D | 1 |
| Nachtigal, A | 1 |
| Scharf, Y | 1 |
| Kasper, H | 1 |
| Sommer, H | 1 |
| Kühn, HA | 1 |
| Drenick, EJ | 2 |
| Ament, ME | 1 |
| Finegold, SM | 1 |
| Passaro, E | 1 |
| Roslyn, JJ | 1 |
1 review available for metronidazole and Arthritis
| Article | Year |
|---|---|
Sternoclavicular joint arthritis as the initial presentation of Crohn's disease in an adolescent.
Topics: Adolescent; Arthralgia; Arthritis; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination | 2013 |
5 other studies available for metronidazole and Arthritis
| Article | Year |
|---|---|
[ON THE SYMPTOMATOLOGY AND THERAPY OF TRICHOMONIASIS].
Topics: Arthritis; Female; Humans; Imidazoles; Leukorrhea; Metronidazole; Trichomonas Infections; Trichomona | 1964 |
Arthritis as the presenting symptom of diverticulitis.
Topics: Arthritis; Colonic Diseases; Colonoscopy; Diagnosis, Differential; Disease-Free Survival; Diverticul | 1997 |
Therapy of Crohn's disease with metronidazole -- an uncontrolled trial --.
Topics: Adolescent; Adult; Arthritis; Crohn Disease; Female; Humans; Male; Metronidazole; Middle Aged; Uveit | 1979 |
Bypass enteropathy: an inflammatory process in the excluded segment with systemic complications.
Topics: Adult; Albumins; Arthritis; Body Weight; Dermatitis; Diarrhea; Female; Humans; Ileum; Inflammation; | 1977 |
Cure of arthritis-dermatitis syndrome due to intestinal bypass by resection of nonfunctional segment of blind loop.
Topics: Arthritis; Blind Loop Syndrome; Dermatitis; Female; Humans; Jejunoileal Bypass; Metronidazole; Middl | 1990 |