metronidazole has been researched along with Arthritides, Bacterial in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although septic arthritis in neonates is a known clinical entity, it is a diagnostic dilemma for the paediatricians." | 1.51 | Clostridium septicum arthritis in a young infant: A case report. ( Angrup, A; Bala, K; Grover, P; Muralidharan, J; Ray, P, 2019) |
| "We are reporting the first case of septic arthritis due to Prevotella bivia in a patient with no pre-existing joint symptoms." | 1.35 | Septic arthritis of the knee joint secondary to Prevotella bivia. ( Baharoon, SA; Salman, SA, 2009) |
| "Metronidazole was added to his treatment regime." | 1.35 | Septic arthritis in a native joint due to Anaerococcus prevotii. ( Bui, V; Jain, S; Spencer, C; Yee, L, 2008) |
| "We report the first case of septic arthritis due to Prevotella bivia in a patient with severe, long-lasting rheumatoid arthritis (RA) treated with low doses of corticosteroids." | 1.31 | Septic arthiritis due to Prevotella bivia in a patient with rheumatoid arthritis. ( Alegre-Sancho, JJ; Juanola, X; Narvaez, FJ; Roig-Escofet, D, 2000) |
| "Radiography revealed septic arthritis of the distal interphalangeal joint and osteomyelitis of the distal and middle phalanges." | 1.29 | Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull. ( Hendrickson, DA; Klohnen, AA; Stone, WC; Trostle, SS, 1996) |
| "Gram-negative septic arthritis is an uncommon but serious complication of rheumatoid arthritis and is usually mono-articular." | 1.26 | Septic polyarthritis due to Bacteroides fragilis in a patient with rheumatoid arthritis. A case report. ( Pretorius, JA; Schorn, D, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, H | 1 |
| Amir, W | 1 |
| Bolick, NL | 1 |
| Grover, P | 1 |
| Bala, K | 1 |
| Muralidharan, J | 1 |
| Angrup, A | 1 |
| Ray, P | 1 |
| Salman, SA | 1 |
| Baharoon, SA | 1 |
| Jain, S | 1 |
| Bui, V | 1 |
| Spencer, C | 1 |
| Yee, L | 1 |
| Dodd, MJ | 1 |
| Griffiths, ID | 1 |
| Freeman, R | 1 |
| Sattar, MA | 1 |
| Sankey, MG | 1 |
| Cawley, MI | 1 |
| Kaye, CM | 1 |
| Holt, JE | 1 |
| Schorn, D | 1 |
| Pretorius, JA | 1 |
| Konstantopoulos, K | 1 |
| Avlami, A | 1 |
| Demarongona, K | 1 |
| Sideris, G | 1 |
| Rekoumi, L | 1 |
| Stefanou, J | 1 |
| Voskaridou, E | 1 |
| Loukopoulos, D | 1 |
| Carlson, ER | 1 |
| Bergamo, DF | 1 |
| Coccia, CT | 1 |
| Trostle, SS | 1 |
| Hendrickson, DA | 1 |
| Stone, WC | 1 |
| Klohnen, AA | 1 |
| Calvo-Alén, J | 1 |
| Pinillos, V | 1 |
| del Val, N | 1 |
| Rodríguez Valverde, V | 1 |
| Alegre-Sancho, JJ | 1 |
| Juanola, X | 1 |
| Narvaez, FJ | 1 |
| Roig-Escofet, D | 1 |
| Nehra, A | 1 |
| Mehta, RN | 1 |
| Encarnacion, C | 1 |
| Oo, MM | 1 |
| Win, KM | 1 |
| Naing, KM | 1 |
| Kaneda, Y | 1 |
| Tanaka, T | 1 |
| Brouqui, P | 1 |
| Richard, P | 1 |
| Lee, MG | 1 |
| Rawlins, SC | 1 |
| Didier, M | 1 |
| DeCeulaer, K | 1 |
| Clarke, HJ | 1 |
| Allum, R | 1 |
| Finegold, SM | 1 |
| Rosenblatt, JE | 1 |
2 reviews available for metronidazole and Arthritides, Bacterial
| Article | Year |
|---|---|
Isolation of Entamoeba histolytica from arthritic knee joint.
Topics: Administration, Oral; Adult; Animals; Antiparasitic Agents; Arthritis, Infectious; Entamoeba histoly | 1992 |
Anaerobic septic arthritis due to bacteroides: brief report.
Topics: Adult; Arthritis, Infectious; Bacteroides Infections; Female; Humans; Knee Joint; Metronidazole | 1988 |
16 other studies available for metronidazole and Arthritides, Bacterial
| Article | Year |
|---|---|
An uncommon case of native joint septic arthritis by Parvimonas micra.
Topics: Aged; Anti-Bacterial Agents; Arthritis, Infectious; Crowns; Firmicutes; Gram-Positive Bacterial Infe | 2021 |
Clostridium septicum arthritis in a young infant: A case report.
Topics: Anti-Infective Agents; Arthritis, Infectious; Clostridium Infections; Clostridium septicum; Debridem | 2019 |
Septic arthritis of the knee joint secondary to Prevotella bivia.
Topics: Aged; Anti-Infective Agents; Arthritis, Infectious; Bacteroidaceae Infections; Humans; Knee Joint; M | 2009 |
Septic arthritis in a native joint due to Anaerococcus prevotii.
Topics: Adult; Anti-Bacterial Agents; Arthritis, Infectious; Bacteria, Anaerobic; Bacterial Infections; Drug | 2008 |
Pyogenic arthritis due to bacteroides complicating rheumatoid arthritis.
Topics: Aged; Arthritis, Infectious; Arthritis, Rheumatoid; Bacteroides fragilis; Bacteroides Infections; Fe | 1982 |
The penetration of metronidazole into synovial fluid.
Topics: Administration, Oral; Adult; Aged; Arthritis, Infectious; Bacterial Infections; Bacteroides fragilis | 1982 |
Septic polyarthritis due to Bacteroides fragilis in a patient with rheumatoid arthritis. A case report.
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Bacteroides fragilis; Bacteroides Infections; Female; | 1982 |
Bacteroides fragilis arthritis in a sickle cell-thalassaemia patient.
Topics: Adult; Anemia, Sickle Cell; Arthritis, Infectious; Bacteroides fragilis; Bacteroides Infections; Chl | 1994 |
Lemierre's syndrome: two cases of a forgotten disease.
Topics: Adolescent; Arthritis, Infectious; Bacteremia; Cefoxitin; Clindamycin; Fusobacterium Infections; Fus | 1994 |
Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull.
Topics: Actinomyces; Actinomycosis; Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory | 1996 |
Pyomyositis and septic arthritis due to Bacteroides fragilis in an immunocompetent patient.
Topics: Aged; Arthritis, Infectious; Bacteroides fragilis; Bacteroides Infections; Drug Therapy, Combination | 1995 |
Septic arthiritis due to Prevotella bivia in a patient with rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Aged; Arthritis, Infectious; Arthritis, Rheumatoid; Bacteroidaceae Infectio | 2000 |
Bacteroides fragilis arthritis in a patient with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Anti-Bacterial Agents; Arthritis, Infectious; Bacteroides fragilis; Bact | 2001 |
[Articular manifestations of Giardia lamblia infections].
Topics: Adolescent; Arthritis, Infectious; Giardiasis; Humans; Male; Metronidazole | 1990 |
Infective arthritis due to Blastocystis hominis.
Topics: Adult; Arthritis, Infectious; Arthritis, Rheumatoid; Female; Humans; Intestinal Diseases, Parasitic; | 1990 |
Practical aspects of anaerobic sepsis.
Topics: Abscess; Anaerobiosis; Arthritis, Infectious; Bacterial Infections; Bacteroides; Bone Diseases; Brai | 1973 |