Page last updated: 2024-10-31

metronidazole and Arthralgia

metronidazole has been researched along with Arthralgia in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Arthralgia: Pain in the joint.

Research Excerpts

ExcerptRelevanceReference
"Abdominal pain is common feature of Henoch-Schonlein purpura, which may mimic appendicitis, leading to unnecessary laparotomy."1.35Gangrenous appendicitis in a child with Henoch-Schonlein purpura. ( Amouzeshi, A; Jalali, AN; Jangjoo, A, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jangjoo, A1
Amouzeshi, A1
Jalali, AN1
Thomas, KS1
Ray, LI1
Giles, HW1
Nowicki, MJ1

Reviews

1 review available for metronidazole and Arthralgia

ArticleYear
Sternoclavicular joint arthritis as the initial presentation of Crohn's disease in an adolescent.
    Clinical pediatrics, 2013, Volume: 52, Issue:8

    Topics: Adolescent; Arthralgia; Arthritis; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combination

2013

Other Studies

1 other study available for metronidazole and Arthralgia

ArticleYear
Gangrenous appendicitis in a child with Henoch-Schonlein purpura.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:11

    Topics: Abdominal Pain; Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Arthralgia; Ceftriaxo

2008