metronidazole has been researched along with Aqueductal Stenosis in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the human teratogenic potential of vaginal metronidazole treatment during pregnancy." | 7.73 | Teratogenic potential of vaginal metronidazole treatment during pregnancy. ( Czeizel, AE; Kazy, Z; Puhó, E, 2005) |
| "To study the human teratogenic potential of vaginal metronidazole treatment during pregnancy." | 3.73 | Teratogenic potential of vaginal metronidazole treatment during pregnancy. ( Czeizel, AE; Kazy, Z; Puhó, E, 2005) |
| "A case of unilateral hydrocephalus due to an abscess in the ipsilateral choroid plexuses, and revealed by intracranial hypertension is reported." | 1.28 | [Unilateral hydrocephalus caused by abscess of the choroid plexus]. ( Artru, F; Jourdan, C; Naous, H; Peloux, A; Remond, J; Terrier, A; Vighettho, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kazy, Z | 1 |
| Puhó, E | 1 |
| Czeizel, AE | 1 |
| Vajramani, GV | 1 |
| Akrawi, H | 1 |
| Jones, G | 1 |
| Sparrow, OC | 1 |
| Commins, DJ | 1 |
| Koay, B | 1 |
| Milford, CA | 1 |
| Renowden, S | 1 |
| Terrier, A | 1 |
| Jourdan, C | 1 |
| Remond, J | 1 |
| Vighettho, A | 1 |
| Peloux, A | 1 |
| Naous, H | 1 |
| Artru, F | 1 |
4 other studies available for metronidazole and Aqueductal Stenosis
| Article | Year |
|---|---|
Teratogenic potential of vaginal metronidazole treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Administration, Intravaginal; Adult; Anti-Infective Agents, Local; Case | 2005 |
Primary ventriculitis caused by Streptococcus intermedius.
Topics: Anti-Infective Agents; Cefotaxime; Cerebral Ventricles; Encephalitis; Endoscopy; Glasgow Coma Scale; | 2007 |
Otitic hydrocephalus.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Cefotaxime; Cephalosporins; Child; Humans; Hydrocepha | 1997 |
[Unilateral hydrocephalus caused by abscess of the choroid plexus].
Topics: Adult; Brain Abscess; Ceftriaxone; Choroid Plexus; Drug Therapy, Combination; Humans; Hydrocephalus; | 1992 |