metronidazole has been researched along with Appetite Disorders in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (60.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Desoubeaux, G | 1 |
Chaussade, H | 1 |
Thellier, M | 1 |
Poussing, S | 1 |
Bastides, F | 1 |
Bailly, E | 1 |
Lanotte, P | 1 |
Alison, D | 1 |
Brunereau, L | 1 |
Bernard, L | 1 |
Chandenier, J | 1 |
Fortunat, S | 1 |
Stiglbauer, W | 1 |
Röggla, G | 1 |
Jones, DI | 1 |
Matveev, VF | 1 |
Vorob'ev, VS | 1 |
Khambatta, RB | 1 |
1 trial available for metronidazole and Appetite Disorders
Article | Year |
---|---|
The effect of metronidazole on exophthalmos in man.
Topics: Antithyroid Agents; Clinical Trials as Topic; Exophthalmos; Feeding and Eating Disorders; Humans; Hy | 1968 |
4 other studies available for metronidazole and Appetite Disorders
Article | Year |
---|---|
Unusual multiple large abscesses of the liver: interest of the radiological features and the real-time PCR to distinguish between bacterial and amebic etiologies.
Topics: Adult; Antibodies, Protozoan; Antiprotozoal Agents; Asthenia; Diarrhea; Dysentery, Amebic; Entamoeba | 2014 |
Giardiasis in a geriatric patient in Austria.
Topics: Aged; Antiprotozoal Agents; Austria; Emaciation; Feeding and Eating Disorders; Female; Giardiasis; H | 2004 |
[Experience with treatment of chronic alcoholism patients with large doses of metronidazole in psychoneurologic dispensaries].
Topics: Adult; Alcoholism; Apomorphine; Chronic Disease; Fatigue; Feeding and Eating Disorders; Humans; Male | 1969 |
Metronidazole in giardiasis.
Topics: Adult; Electrocardiography; Fatigue; Feeding and Eating Disorders; Giardiasis; Humans; Metronidazole | 1971 |