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metronidazole and Ape Diseases

metronidazole has been researched along with Ape Diseases in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Ape Diseases: Diseases of chimpanzees, gorillas, and orangutans.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Halbwax, M1
Mahamba, CK1
Ngalula, AM1
André, C1
Lankester, F1
Kiyang, JA1
Bailey, W1
Unwin, S1

Other Studies

2 other studies available for metronidazole and Ape Diseases

ArticleYear
Placental retention in a bonobo (Pan paniscus).
    Journal of medical primatology, 2009, Volume: 38, Issue:3

    Topics: Amoxicillin; Animals; Animals, Zoo; Ape Diseases; Female; Metronidazole; Oxytocin; Pan paniscus; Pla

2009
Dientamoeba fragilis: initial evidence of pathogenicity in the western lowland gorilla (Gorilla gorilla gorilla).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2010, Volume: 41, Issue:2

    Topics: Animals; Antiprotozoal Agents; Ape Diseases; Dientamoeba; Dientamoebiasis; Feces; Female; Gorilla go

2010