Page last updated: 2024-10-31

metronidazole and Anxiety

metronidazole has been researched along with Anxiety in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
O'Connor, R1
Moloney, GM1
Fulling, C1
O'Riordan, KJ1
Fitzgerald, P1
Bastiaanssen, TFS1
Schellekens, H1
Dinan, TG1
Cryan, JF1
Soto, M1
Herzog, C1
Pacheco, JA1
Fujisaka, S1
Bullock, K1
Clish, CB1
Kahn, CR1
Zamudio-Tiburcio, Á1
Bermúdez-Ruiz, H1
Lezama-Guzmán, HR1
Guevara-Ortigoza, MDP1
Islas-Solares, E1
Sosa-López, FA1
Kissin, B1
Gross, MM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients[NCT04179006]120 participants (Anticipated)Interventional2019-11-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for metronidazole and Anxiety

ArticleYear
Maternal antibiotic administration during a critical developmental window has enduring neurobehavioural effects in offspring mice.
    Behavioural brain research, 2021, 04-23, Volume: 404

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anxiety; Ciprofloxacin; Cognition; Female; Homing Behavi

2021
Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism.
    Molecular psychiatry, 2018, Volume: 23, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Anxiety; Brain; Diet, High-Fat; Gastrointestinal Microbiome; Inflamm

2018
[Breaking paradigms. Intestinal microbiota transplantation: Preliminar report].
    Cirugia y cirujanos, 2017, Volume: 85 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Celiac Disease; Colon; Comorbidity; Contraindications, Drug

2017
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox

1970