metronidazole has been researched along with Anxiety in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors | Studies |
---|---|
O'Connor, R | 1 |
Moloney, GM | 1 |
Fulling, C | 1 |
O'Riordan, KJ | 1 |
Fitzgerald, P | 1 |
Bastiaanssen, TFS | 1 |
Schellekens, H | 1 |
Dinan, TG | 1 |
Cryan, JF | 1 |
Soto, M | 1 |
Herzog, C | 1 |
Pacheco, JA | 1 |
Fujisaka, S | 1 |
Bullock, K | 1 |
Clish, CB | 1 |
Kahn, CR | 1 |
Zamudio-Tiburcio, Á | 1 |
Bermúdez-Ruiz, H | 1 |
Lezama-Guzmán, HR | 1 |
Guevara-Ortigoza, MDP | 1 |
Islas-Solares, E | 1 |
Sosa-López, FA | 1 |
Kissin, B | 1 |
Gross, MM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients[NCT04179006] | 120 participants (Anticipated) | Interventional | 2019-11-14 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 other studies available for metronidazole and Anxiety
Article | Year |
---|---|
Maternal antibiotic administration during a critical developmental window has enduring neurobehavioural effects in offspring mice.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anxiety; Ciprofloxacin; Cognition; Female; Homing Behavi | 2021 |
Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism.
Topics: Animals; Anti-Bacterial Agents; Anxiety; Brain; Diet, High-Fat; Gastrointestinal Microbiome; Inflamm | 2018 |
[Breaking paradigms. Intestinal microbiota transplantation: Preliminar report].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Celiac Disease; Colon; Comorbidity; Contraindications, Drug | 2017 |
Drug therapy in alcoholism.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox | 1970 |