metronidazole has been researched along with Anus Prolapse in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Day-case rate, postoperative pain (measured by a visual analogic scale, 1-10), admissions, re-admissions, early postoperative situation and recurrence were evaluated in the study." | 1.38 | Day case stapled anopexy for the treatment of haemorrhoids and rectal mucosal prolapse. ( Carbonell Roure, J; Estrada Ferrer, O; García Torralbo, E; Heredia Budó, A; Hidalgo Grau, LA; Llorca Cardeñosa, S; Suñol Sala, X, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cares, K | 1 |
| El-Baba, M | 1 |
| Hidalgo Grau, LA | 1 |
| Heredia Budó, A | 1 |
| Llorca Cardeñosa, S | 1 |
| Carbonell Roure, J | 1 |
| Estrada Ferrer, O | 1 |
| García Torralbo, E | 1 |
| Suñol Sala, X | 1 |
| Harris, PR | 1 |
| Figueroa-Colon, R | 1 |
| Houry, S | 1 |
| Bhandari, B | 2 |
| Sankhla, K | 1 |
| Mandowara, SL | 1 |
6 other studies available for metronidazole and Anus Prolapse
| Article | Year |
|---|---|
A 9-Month-Old Presenting With Rectal Prolapse.
Topics: Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; Female; Follow-Up Studies; Humans; | 2016 |
Day case stapled anopexy for the treatment of haemorrhoids and rectal mucosal prolapse.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Anti-Infective Agents; Antib | 2012 |
Rectal prolapse in children associated with Clostridium difficile infection.
Topics: Child, Preschool; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Humans; Metroni | 1995 |
[Delorme procedure for rectal prolapse].
Topics: Age Factors; Aged; Anti-Infective Agents; Frail Elderly; Humans; Metronidazole; Postoperative Care; | 2000 |
Amoebiasis and rectal prolapse in children.
Topics: Child; Child, Preschool; Dysentery, Amebic; Female; Humans; Infant; Iodoquinol; Male; Metronidazole; | 1979 |
Rectal prolapse.
Topics: Amebiasis; Child; Child, Preschool; Dysentery, Bacillary; Humans; Infant; Infant, Newborn; Iodoquino | 1985 |