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metronidazole and Anterior Optic Neuritis

metronidazole has been researched along with Anterior Optic Neuritis in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Putnam, D1
Fraunfelder, FT1
Dreis, M1
Sucs, FE1
Zanen, A1
Pittman, F1
Westphal, M1
Shookhoff, HB1
Katz, M1

Other Studies

4 other studies available for metronidazole and Anterior Optic Neuritis

ArticleYear
Metronidazole and optic neuritis.
    American journal of ophthalmology, 1991, Dec-15, Volume: 112, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Humans; Metronidazole; Optic Neuritis

1991
[Ocular manifestations secondary to giardiasis].
    Bulletin de la Societe belge d'ophtalmologie, 1986, Volume: 219

    Topics: Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Edema; Female; Giardiasis; Humans; Intest

1986
S.M.O.N. and inflammation of the colon.
    Lancet (London, England), 1973, Sep-08, Volume: 2, Issue:7828

    Topics: Abdomen; Amblyopia; Child; Colitis; Diarrhea; Female; Humans; Intestinal Absorption; Iodoquinol; Kid

1973
Letter: S.M.O.N. and inflammation of the colon.
    Lancet (London, England), 1973, Nov-10, Volume: 2, Issue:7837

    Topics: Abdomen; Adult; Amebiasis; Child; Colitis; Diarrhea; Drug Evaluation; Humans; Iodoquinol; Metronidaz

1973