metronidazole has been researched along with Anorexia in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan." | 9.12 | Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. ( Alizadeh, A; Bodaghi, M; Kashani, KM; Ranjbar, M; Taheri, MM, 2006) |
| " In an open, randomized parallel group study, the safety and efficacy of albendazole was compared with that of metronidazole for the treatment of giardiasis in children." | 9.08 | A comparative clinical trial of albendazole versus metronidazole in giardiasis. ( Agarwal, V; Jagota, SC; Kumar, A; Misra, PK, 1995) |
| " In an open, randomized parallel group study, the safety and efficacy of albendazole was compared with metronidazole for the treatment of giardiasis in children." | 9.08 | A comparative clinical trial of albendazole versus metronidazole in children with giardiasis. ( Agarwal, V; Jagota, SC; Kumar, A; Misra, PK, 1995) |
| "We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan." | 5.12 | Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. ( Alizadeh, A; Bodaghi, M; Kashani, KM; Ranjbar, M; Taheri, MM, 2006) |
| " In an open, randomized parallel group study, the safety and efficacy of albendazole was compared with that of metronidazole for the treatment of giardiasis in children." | 5.08 | A comparative clinical trial of albendazole versus metronidazole in giardiasis. ( Agarwal, V; Jagota, SC; Kumar, A; Misra, PK, 1995) |
| " In an open, randomized parallel group study, the safety and efficacy of albendazole was compared with metronidazole for the treatment of giardiasis in children." | 5.08 | A comparative clinical trial of albendazole versus metronidazole in children with giardiasis. ( Agarwal, V; Jagota, SC; Kumar, A; Misra, PK, 1995) |
| "Seventy-eight patients with active Crohn's disease participated in a randomized, double-blind, cross-over trial." | 2.65 | A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result. ( Alm, T; Bárány, F; Bergelin, I; Ganrot-Norlin, K; Hoevels, J; Huitfeldt, B; Järnerot, G; Krause, U; Krook, A; Lindström, B; Nordle, O; Rosén, A; Ursing, B, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collis, DH | 1 |
| Sanu, A | 1 |
| Çekin, AH | 1 |
| Şahintürk, Y | 1 |
| Akbay Harmandar, F | 1 |
| Uyar, S | 1 |
| Yolcular, BO | 1 |
| Çekin, Y | 1 |
| Alizadeh, A | 1 |
| Ranjbar, M | 1 |
| Kashani, KM | 1 |
| Taheri, MM | 1 |
| Bodaghi, M | 1 |
| Ursing, B | 1 |
| Alm, T | 1 |
| Bárány, F | 1 |
| Bergelin, I | 1 |
| Ganrot-Norlin, K | 1 |
| Hoevels, J | 1 |
| Huitfeldt, B | 1 |
| Järnerot, G | 1 |
| Krause, U | 1 |
| Krook, A | 1 |
| Lindström, B | 1 |
| Nordle, O | 1 |
| Rosén, A | 1 |
| Hayes, JG | 1 |
| Misra, PK | 2 |
| Kumar, A | 2 |
| Agarwal, V | 2 |
| Jagota, SC | 2 |
5 trials available for metronidazole and Anorexia
| Article | Year |
|---|---|
Use of probiotics as an adjuvant to sequential H. pylori eradication therapy: impact on eradication rates, treatment resistance, treatment-related side effects, and patient compliance.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Amoxicillin; Anorexia; Anti-Bacteria | 2017 |
Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran.
Topics: Adolescent; Adult; Albendazole; Anorexia; Antiprotozoal Agents; Child; Child, Preschool; Drug Admini | 2006 |
A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the cooperative Crohn's disease study in Sweden. II. Result.
Topics: Adult; Anorexia; Blood Sedimentation; Clinical Trials as Topic; Crohn Disease; Double-Blind Method; | 1982 |
A comparative clinical trial of albendazole versus metronidazole in giardiasis.
Topics: Albendazole; Anorexia; Antiprotozoal Agents; Child; Child, Preschool; Female; Giardiasis; Humans; Ma | 1995 |
A comparative clinical trial of albendazole versus metronidazole in children with giardiasis.
Topics: Albendazole; Anorexia; Antiprotozoal Agents; Child; Child, Preschool; Female; Giardiasis; Humans; In | 1995 |
2 other studies available for metronidazole and Anorexia
| Article | Year |
|---|---|
Zygomatic haematoma in an 11-month-old helps diagnose retropharyngeal abscess, with concurrent tonsillitis and subsequent infant tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anorexia; Anti-Bacterial Agents; Cefotaxime; Dexamethasone; | 2016 |
Amoebic liver abscess: clinical presentation and diagnosis.
Topics: Abdomen; Adult; Aged; Anorexia; Body Weight; Female; Fever; Humans; Liver Abscess, Amebic; Male; Met | 1980 |