metronidazole has been researched along with Anorexia Nervosa in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Anorexia Nervosa: An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic giardiasis is a rare and enigmatic disease that presents with many symptoms similar to chronic gastrointestinal disorders (e." | 1.40 | An adolescent with chronic giardiasis mimicking anorexia nervosa. ( Thomas Iv, LJ; Tosh, AK; Zweig, AP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas Iv, LJ | 1 |
| Zweig, AP | 1 |
| Tosh, AK | 1 |
| Seinson, RP | 1 |
1 trial available for metronidazole and Anorexia Nervosa
| Article | Year |
|---|---|
Long term trial of metronidazole in male alcoholics.
Topics: Alcoholism; Anorexia Nervosa; Clinical Trials as Topic; Follow-Up Studies; Humans; Male; Metronidazo | 1971 |
1 other study available for metronidazole and Anorexia Nervosa
| Article | Year |
|---|---|
An adolescent with chronic giardiasis mimicking anorexia nervosa.
Topics: Adolescent; Anorexia Nervosa; Antiprotozoal Agents; Chronic Disease; Diagnosis, Differential; Female | 2014 |