Page last updated: 2024-10-31

metronidazole and Angioedema

metronidazole has been researched along with Angioedema in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Angioedema: Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dilley, M1
Geng, B1
Asensio Sánchez, T1
Dávila, I1
Moreno, E1
Laffond, E1
Macías, E1
Ruiz, A1
Lorente, F1
Farkas, H1
Gyeney, L1
Majthényi, P1
Füst, G1
Varga, L1
Shevliakov, LV1

Reviews

1 review available for metronidazole and Angioedema

ArticleYear
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
    Clinical reviews in allergy & immunology, 2022, Volume: 62, Issue:3

    Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic C

2022

Other Studies

3 other studies available for metronidazole and Angioedema

ArticleYear
Anaphylaxis due to metronidazole with positive skin prick test.
    Journal of investigational allergology & clinical immunology, 2008, Volume: 18, Issue:2

    Topics: Anaphylaxis; Angioedema; Drug Hypersensitivity; Female; Humans; Metronidazole; Middle Aged; Skin Tes

2008
Angioedema due to acquired C1-esterase inhibitor deficiency in a patient with Helicobacter pylori infection.
    Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:6

    Topics: Adult; Angioedema; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; C

1999
[Recurrent Quincke's edema caused by trichopal].
    Vestnik dermatologii i venerologii, 1978, Issue:2

    Topics: Adult; Angioedema; Humans; Male; Metronidazole; Recurrence

1978