metronidazole has been researched along with Angiitis in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Excerpt | Relevance | Reference |
---|---|---|
"Here we present a case of fulminant amoebic colitis in a patient with SLE which was initially misdiagnosed as ischemic colitis due to intestinal vasculitis." | 1.38 | Fulminant amoebic colitis mimicking intestinal vasculitis in a patient with systemic lupus erythematosus. ( Ju, JH; Jung, HS; Kim, HY; Kwok, SK; Lee, J; Nam, HC; Park, KS; Park, SH, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Briongos-Figuero, LS | 1 |
Bachiller-Luque, P | 1 |
Pastor-Mancisidor, L | 1 |
Carreres-Rodríguez, A | 1 |
Mena-Martín, FJ | 1 |
Treszezamsky, AD | 1 |
Feldman, D | 1 |
Sarabanchong, VO | 1 |
Lee, J | 1 |
Jung, HS | 1 |
Nam, HC | 1 |
Kwok, SK | 1 |
Ju, JH | 1 |
Park, KS | 1 |
Kim, HY | 1 |
Park, SH | 1 |
Mathieson, PW | 1 |
Thiru, S | 1 |
Oliveira, DB | 1 |
4 other studies available for metronidazole and Angiitis
Article | Year |
---|---|
[Cerebellar syndrome induced by metronidazole: a rare side effect].
Topics: Anti-Bacterial Agents; Brain Abscess; Cefotaxime; Cephalosporins; Cerebellar Ataxia; Diagnosis, Diff | 2016 |
Concurrent postpartum uterine and abdominal wall dehiscence and Streptococcus anginosus infection.
Topics: Abdominal Wall; Acute Disease; Adolescent; Anti-Bacterial Agents; Ascitic Fluid; Cefazolin; Cesarean | 2011 |
Fulminant amoebic colitis mimicking intestinal vasculitis in a patient with systemic lupus erythematosus.
Topics: Antiprotozoal Agents; Colitis, Ischemic; Diagnosis, Differential; Diagnostic Errors; Dysentery, Ameb | 2012 |
Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis.
Topics: Animals; Autoantibodies; Basement Membrane; Colon; Duodenum; Ivermectin; Kidney Glomerulus; Male; Me | 1992 |