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metronidazole and Anesthesia

metronidazole has been researched along with Anesthesia in 1 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ray, DE1
Holton, JL1
Lister, T1
Nolan, CC1

Other Studies

1 other study available for metronidazole and Anesthesia

ArticleYear
The glio-vascular toxicity of m-dinitrobenzene and related agents: modulation of toxicity by neuronal activation.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1996, Volume: 18

    Topics: 6-Aminonicotinamide; Analysis of Variance; Anesthesia; Animals; Auditory Cortex; Auditory Threshold;

1996