metronidazole has been researched along with Anemia in 11 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results are reported of a clinical trial on the effect of metronidazole as an adjuvant radiosensitizer in the radiation treatment of cervix carcinomas in advanced stages." | 5.06 | Anaemia as a prognostic factor for the therapeutic effect of radiosensitizers. ( Balmukhanov, SB; Révész, L, 1987) |
| "The authors report a case of massive Trichuris trichiura infection, resulting in severe anaemia and congestive cardiac failure in a 9-year-old Iban boy, who was resistant to the usual oral anthelmintic treatment, but promptly responded to mebendazole retention enema." | 3.67 | Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report. ( Bhattacharya, S; Ray, S; Sebastian, VJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vipani, A | 1 |
| Yang, MX | 1 |
| Smith, PT | 1 |
| Niakara, A | 1 |
| Bougouma, A | 1 |
| Cisse, R | 1 |
| LUBBER, GJ | 1 |
| MACGILLAVRAY, I | 1 |
| el-Nahas, AF | 1 |
| el-Ashmawy, IM | 1 |
| Jiménez, JC | 1 |
| Rodríguez, N | 1 |
| Di Prisco, MC | 1 |
| Lynch, NR | 1 |
| Costa, V | 1 |
| Sebastian, VJ | 1 |
| Bhattacharya, S | 1 |
| Ray, S | 1 |
| Révész, L | 1 |
| Balmukhanov, SB | 2 |
| Rismukhamedova, RS | 1 |
| Abdrakhmanov, ZhN | 1 |
| Musapirova, NA | 1 |
| Aĭtkulova, Z | 1 |
| Lapierre, J | 1 |
1 review available for metronidazole and Anemia
| Article | Year |
|---|---|
ADVANCES IN OBSTETRICS AND GYNAECOLOGY.
Topics: Anemia; Antineoplastic Agents; Choriocarcinoma; Contraceptive Agents; Contraceptives, Oral; Female; | 1964 |
2 trials available for metronidazole and Anemia
| Article | Year |
|---|---|
Anaemia as a prognostic factor for the therapeutic effect of radiosensitizers.
Topics: Anemia; Carcinoma; Female; Humans; Metronidazole; Prognosis; Radiation-Sensitizing Agents; Uterine C | 1987 |
[Hemoglobin level--a prognostic factor of the effectiveness of metronidazole in radiotherapy of cancer of the cervix uteri].
Topics: Anemia; Clinical Trials as Topic; Female; Hemoglobins; Humans; Metronidazole; Middle Aged; Prognosis | 1986 |
8 other studies available for metronidazole and Anemia
| Article | Year |
|---|---|
Intestinal Spirochetosis Masquerading as Inflammatory Bowel Disease.
Topics: Adult; Anemia; Anti-Bacterial Agents; Brachyspira; Delayed Diagnosis; Diagnosis, Differential; Gastr | 2019 |
Case of the month. MALT lymphoma.
Topics: Anemia; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Cyclophosphamide; Drug Therapy, Co | 2010 |
[A case of pneumopericardium complicating a liver abscess in a patient infected with HIV].
Topics: Adult; AIDS-Related Opportunistic Infections; Amoxicillin; Anemia; Anti-Infective Agents; Blood Tran | 1999 |
[TREATMENT OF TRICHOMONAS INFECTION WITH METRONIDAZOL (FLAGYL) AND THE BLOOD PICTURE].
Topics: Anemia; Blood Cell Count; Female; Humans; Imidazoles; Leukopenia; Metronidazole; Toxicology; Trichom | 1963 |
Reproductive and cytogenetic toxicity of metronidazole in male mice.
Topics: Anemia; Animals; Anti-Infective Agents; Bone Marrow Cells; Chromosome Aberrations; Dose-Response Rel | 2004 |
Haemoglobin concentrations and infection by Giardia intestinalis in children: effect of treatment with secnidazole.
Topics: Anemia; Antiprotozoal Agents; Case-Control Studies; Child; Child, Preschool; Female; Giardiasis; Hem | 1999 |
Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report.
Topics: Anemia; Brunei; Child; Enema; Entamoebiasis; Heart Failure; Humans; Male; Mebendazole; Metronidazole | 1989 |
[Leishmaniasis].
Topics: Amidines; Amphotericin B; Anemia; Animals; Antimony; Blood Protein Electrophoresis; Child, Preschool | 1969 |