metronidazole has been researched along with Anemia, Iron-Deficiency in 16 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Anemia, Iron-Deficiency: Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the effects of giardiasis treatment on hematological indices in children in the Khuzestan area by comparing these indices before and after treatment with metronidazole." | 5.13 | Comparison of iron and hematological indices in Giardia lamblia infection before and after treatment in 102 children in Ahwaz, Iran. ( Monajemzadeh, M; Monajemzadeh, SM, 2008) |
| "Treatment of H pylori can enhance the efficacy of ferrous succinate therapy in IDA patients with H pylori-positive chronic gastritis." | 5.12 | Effects of H pylori therapy on erythrocytic and iron parameters in iron deficiency anemia patients with H pylori-positive chronic gastristis. ( Chen, LH; Luo, HS, 2007) |
| " Given the histology and the fact that rapid urease test results were positive, chronic active gastritis with H." | 3.70 | Iron-deficiency anemia associated with Helicobacter pylori gastritis. ( Imai, T; Konno, M; Muraoka, S; Takahashi, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, DS | 1 |
| Li, D | 1 |
| Cholleti, SM | 1 |
| Wei, JC | 1 |
| Jodesty, Y | 1 |
| Pham, HV | 1 |
| Nashaat, EH | 1 |
| Mansour, GM | 1 |
| Andrianov, M | 1 |
| Rivera, E | 1 |
| Azzam, R | 1 |
| Okuda, M | 1 |
| Kikuchi, S | 1 |
| Mabe, K | 1 |
| Osaki, T | 1 |
| Kamiya, S | 1 |
| Fukuda, Y | 1 |
| Kato, M | 1 |
| Kasirga, E | 1 |
| Gülen, H | 1 |
| Simşek, A | 1 |
| Ayhan, S | 1 |
| Yilmaz, O | 1 |
| Ellidokuz, E | 1 |
| Selgrad, M | 1 |
| Bornschein, J | 1 |
| Malfertheiner, P | 1 |
| Xia, W | 1 |
| Zhang, X | 1 |
| Wang, J | 1 |
| Sun, C | 1 |
| Wu, L | 1 |
| Lopriore, C | 1 |
| Guidoum, Y | 1 |
| Briend, A | 1 |
| Branca, F | 1 |
| Konno, M | 2 |
| Chen, LH | 1 |
| Luo, HS | 1 |
| Monajemzadeh, SM | 1 |
| Monajemzadeh, M | 1 |
| Marignani, M | 1 |
| Angeletti, S | 1 |
| Bordi, C | 1 |
| Malagnino, F | 1 |
| Mancino, C | 1 |
| Delle Fave, G | 1 |
| Annibale, B | 1 |
| Choe, YH | 1 |
| Kim, SK | 1 |
| Son, BK | 1 |
| Lee, DH | 1 |
| Hong, YC | 1 |
| Pai, SH | 1 |
| Muraoka, S | 1 |
| Takahashi, M | 1 |
| Imai, T | 1 |
| Ashorn, M | 1 |
| Ruuska, T | 1 |
| Mäkipernaa, A | 1 |
| Diouf, S | 1 |
| Diagne, I | 1 |
| Moreira, C | 1 |
| Signate, SY | 1 |
| Faye, O | 1 |
| Ndiaye, O | 1 |
| Sylla, A | 1 |
| Diallo, I | 1 |
| Thiam, D | 1 |
| Diop, B | 1 |
| Thiam, I | 1 |
| Gaye, I | 1 |
| Sarr, M | 1 |
| Fall, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Eradication of H-pylori in Pregnant Patients With Iron Deficiency Anemia Have an Effect on Iron Replacement Therapy?[NCT03347513] | Phase 4 | 150 participants (Anticipated) | Interventional | 2017-11-25 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for metronidazole and Anemia, Iron-Deficiency
| Article | Year |
|---|---|
[Helicobacter pylori: an infection with local complications and systemic effects].
Topics: Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Asthma; Clarithromycin; Cross-Sectional | 2011 |
[Helicobacter pylori eradication therapy for children].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents | 2005 |
6 trials available for metronidazole and Anemia, Iron-Deficiency
| Article | Year |
|---|---|
Survey of anaemia and Helicobacter pylori infection in adolescent girls in Suihua, China and enhancement of iron intervention effects by H. pylori eradication.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodi | 2012 |
Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3-6 y.
Topics: Algeria; Analysis of Variance; Anemia, Iron-Deficiency; Body Height; Child; Child, Preschool; Double | 2004 |
Effects of H pylori therapy on erythrocytic and iron parameters in iron deficiency anemia patients with H pylori-positive chronic gastristis.
Topics: Adolescent; Adult; Aged; Amoxicillin; Anemia, Iron-Deficiency; Anti-Infective Agents; Chronic Diseas | 2007 |
Comparison of iron and hematological indices in Giardia lamblia infection before and after treatment in 102 children in Ahwaz, Iran.
Topics: Anemia, Iron-Deficiency; Antiprotozoal Agents; Child; Child, Preschool; Erythrocyte Indices; Female; | 2008 |
Randomized placebo-controlled trial of Helicobacter pylori eradication for iron-deficiency anemia in preadolescent children and adolescents.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; | 1999 |
Helicobacter pylori and iron deficiency anaemia in children.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath T | 2001 |
8 other studies available for metronidazole and Anemia, Iron-Deficiency
| Article | Year |
|---|---|
Effect of Helicobacter pylori Treatment on Unexplained Iron Deficiency Anemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Age | 2019 |
Helicobacter pylori and anemia with pregnancy.
Topics: Adult; Ampicillin; Anemia, Iron-Deficiency; Anti-Infective Agents; Drug Therapy, Combination; Female | 2014 |
A 15-year-old boy with abdominal pain, growth retardation, and anemia secondary to Helicobacter pylori-associated peptic ulcer.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Clarithromycin; Drug Therapy, Combination; Growth | 2015 |
Nationwide survey of Helicobacter pylori treatment for children and adolescents in Japan.
Topics: Adolescent; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Child; Clarithromycin; Drug | 2017 |
Coexistence of symptomatic iron-deficiency anemia and duodenal nodular lymphoid hyperplasia due to giardiasis: case report.
Topics: Adolescent; Anemia, Iron-Deficiency; Comorbidity; Duodenum; Giardiasis; Humans; Hyperplasia; Intesti | 2009 |
Reversal of long-standing iron deficiency anaemia after eradication of Helicobacter pylori infection.
Topics: Adult; Anemia, Iron-Deficiency; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; Clarithromycin; D | 1997 |
Iron-deficiency anemia associated with Helicobacter pylori gastritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Anemia, Iron-Deficiency; Anti-Bacterial Agents; | 2000 |
[Integrated treatment of iron deficiency, vitamin A deficiency and intestinal parasitic diseases: impact on Senegalese children's growth].
Topics: Anemia, Iron-Deficiency; Anti-Infective Agents; Antinematodal Agents; Child Nutrition Disorders; Chi | 2002 |