metronidazole has been researched along with Anaphylactic Reaction in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the first case of anaphylaxis to oral vancomycin in a cystic fibrosis patient with severe and relapsing Clostridium difficile infection (CDI) refractory to metronidazole." | 7.79 | Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection. ( Bossé, D; Cantin, AM; Lemire, C; Ménard, F; Ruel, J; Valiquette, L, 2013) |
| " The knowledge of adverse effects of antibiotics was greatest for tooth discoloration which is related to tetracycline." | 3.80 | Antibiotics prescription in Nigerian dental healthcare services. ( Azodo, CC; Ojehanon, PI, 2014) |
| "We report the first case of anaphylaxis to oral vancomycin in a cystic fibrosis patient with severe and relapsing Clostridium difficile infection (CDI) refractory to metronidazole." | 3.79 | Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection. ( Bossé, D; Cantin, AM; Lemire, C; Ménard, F; Ruel, J; Valiquette, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dilley, M | 1 |
| Geng, B | 1 |
| Azodo, CC | 1 |
| Ojehanon, PI | 1 |
| Schmutz, JL | 1 |
| Barbaud, A | 1 |
| Tréchot, P | 1 |
| Bossé, D | 1 |
| Lemire, C | 1 |
| Ruel, J | 1 |
| Cantin, AM | 1 |
| Ménard, F | 1 |
| Valiquette, L | 1 |
| Asensio Sánchez, T | 1 |
| Dávila, I | 1 |
| Moreno, E | 1 |
| Laffond, E | 1 |
| Macías, E | 1 |
| Ruiz, A | 1 |
| Lorente, F | 1 |
| Kohli, J | 1 |
| Bhattacharya, SK | 1 |
| Gupta, VS | 1 |
| Sen, P | 1 |
| Chakravarty, AK | 1 |
1 review available for metronidazole and Anaphylactic Reaction
| Article | Year |
|---|---|
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic C | 2022 |
5 other studies available for metronidazole and Anaphylactic Reaction
| Article | Year |
|---|---|
Antibiotics prescription in Nigerian dental healthcare services.
Topics: Acquired Immunodeficiency Syndrome; Amoxicillin; Anaphylaxis; Anti-Bacterial Agents; Antibiotic Prop | 2014 |
[Anaphylactic reaction to metronidazole].
Topics: Anaphylaxis; Female; Humans; Metronidazole; Middle Aged | 2009 |
Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection.
Topics: Administration, Oral; Adult; Anaphylaxis; Anti-Bacterial Agents; Clostridioides difficile; Clostridi | 2013 |
Anaphylaxis due to metronidazole with positive skin prick test.
Topics: Anaphylaxis; Angioedema; Drug Hypersensitivity; Female; Humans; Metronidazole; Middle Aged; Skin Tes | 2008 |
Effect of metronidazole on immune mechanism in experimental animals.
Topics: Anaphylaxis; Animals; Antibody Formation; Female; Hemagglutination; Hypersensitivity; Immunity; Male | 1987 |