Page last updated: 2024-10-31

metronidazole and Allergic Contact Dermatitis

metronidazole has been researched along with Allergic Contact Dermatitis in 9 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Dilley, M1
Geng, B1
Foti, C1
Calianno, G1
Cassano, N1
Vena, GA1
Hansel, K1
Stingeni, L1
Romita, P1
Kumagai, J1
Nakamura, A1
Ogawa, S1
Washio, K1
Fernández-Jorge, B1
Goday Buján, J1
Fernández-Torres, R1
Rodríguez-Lojo, R1
Fonseca, E1
Madsen, JT2
Lorentzen, HF1
Paulsen, E1
Thormann, J1
Kerre, S1
Andersen, KE1
Goossens, A1
Vincenzi, C1
Lucente, P1
Ricci, C1
Tosti, A1
Choudry, K1
Beck, MH1
Muston, HL1
Hjerppe, M1
Karppinen, A1
Hasan, T1

Reviews

1 review available for metronidazole and Allergic Contact Dermatitis

ArticleYear
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
    Clinical reviews in allergy & immunology, 2022, Volume: 62, Issue:3

    Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic C

2022

Other Studies

8 other studies available for metronidazole and Allergic Contact Dermatitis

ArticleYear
Vulvar allergic contact dermatitis to metronidazole.
    Contact dermatitis, 2023, Volume: 88, Issue:5

    Topics: Dermatitis, Allergic Contact; Female; Humans; Metronidazole; Patch Tests; Vulvar Diseases

2023
Intravaginal metronidazole ovule-related allergic contact dermatitis.
    Contact dermatitis, 2021, Volume: 85, Issue:1

    Topics: Administration, Intravaginal; Anti-Bacterial Agents; Dermatitis, Allergic Contact; Dose-Response Rel

2021
Concomitant allergic contact dermatitis from diphenhydramine and metronidazole.
    Contact dermatitis, 2008, Volume: 59, Issue:2

    Topics: Anti-Infective Agents; Dermatitis, Allergic Contact; Diphenhydramine; Drug Eruptions; Drug Therapy,

2008
Contact sensitization to metronidazole from possible occupational exposure.
    Contact dermatitis, 2009, Volume: 60, Issue:2

    Topics: Administration, Topical; Adult; Aged; Carcinoma, Basal Cell; Dermatitis, Allergic Contact; Dermatiti

2009
Allergic contact dermatitis to topical metronidazole - 3 cases.
    Contact dermatitis, 2007, Volume: 56, Issue:6

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Dermatitis, Allergic Contact; Drug Eruptions;

2007
Facial contact dermatitis due to metronidazole.
    Contact dermatitis, 1997, Volume: 36, Issue:2

    Topics: Adult; Antifungal Agents; Dermatitis, Allergic Contact; Drug Eruptions; Facial Dermatoses; Female; H

1997
Allergic contact dermatitis from 2-bromo-2-nitropropane-1,3-diol in Metrogel.
    Contact dermatitis, 2002, Volume: 46, Issue:1

    Topics: Allergens; Anti-Infective Agents; Dermatitis, Allergic Contact; Female; Gels; Humans; Metronidazole;

2002
[Allergic eczema from metronidazole ointment].
    Duodecim; laaketieteellinen aikakauskirja, 2000, Volume: 116, Issue:20

    Topics: Anti-Infective Agents; Dermatitis, Allergic Contact; Female; Humans; Metronidazole; Middle Aged; Oin

2000