metronidazole has been researched along with Alactasia in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Giardia lamblia were found in nine patients and 15 patients responded to an empirical course of either metronidazole or tinidazole, without a positive diagnosis of giardiasis being made." | 3.66 | A prospective study of persistent diarrhoea. ( Bolin, TD; Davis, AE; Duncombe, VM, 1982) |
| "Lactose intolerance is a secondary problem most commonly associated with rotavirus infection, but it can be caused by any condition affecting the small intestine." | 1.30 | Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal. ( Parsons, DA; Staempfli, HR; Weese, JS, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stephens, S | 1 |
| Brown, CD | 1 |
| Wiener, CM | 1 |
| Clements, CJ | 1 |
| Bolin, TD | 1 |
| Davis, AE | 1 |
| Duncombe, VM | 1 |
| Weese, JS | 1 |
| Parsons, DA | 1 |
| Staempfli, HR | 1 |
| Ochs, HD | 2 |
| Ament, ME | 2 |
| Davis, SD | 2 |
6 other studies available for metronidazole and Alactasia
| Article | Year |
|---|---|
Host to an intruder.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antiprotozoal Agents; Diarrhea; Giardia lambl | 2005 |
Metronidazole and breast feeding.
Topics: Breast Feeding; Cesarean Section; Diarrhea, Infantile; Female; Humans; Infant; Infant, Newborn; Lact | 1980 |
A prospective study of persistent diarrhoea.
Topics: Adolescent; Adult; Aged; Colonic Diseases, Functional; Crohn Disease; Diarrhea; Female; Giardiasis; | 1982 |
Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; beta-Galactosidase; Clostridioides difficile; Clos | 1999 |
Structure and function of the gastrointestinal tract in primary immunodeficiency syndromes (IDS) and in granulocyte dysfunction.
Topics: Carotenoids; Crohn Disease; Digestive System; Disaccharidases; Feces; Female; Folic Acid; Gastrointe | 1975 |
Giardiasis with malabsorption in X-linked agammaglobulinemia.
Topics: Agammaglobulinemia; Biopsy; Child; Duodenum; Giardiasis; Humans; Intestinal Absorption; Intestinal M | 1972 |