metronidazole has been researched along with Air Embolism in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histologic examination confirmed Crohn's disease that was associated with vasculitis and, in particular, with thrombophlebitis and subsequent transmural bowel necrosis." | 1.32 | [Pylephlebitis with air in the portal vein system. An unusual focus in a patient with sepsis]. ( Gocht, A; Hahn, KE; Kluge, S; Kreymann, G; Lund, CH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hussain, A | 1 |
| Mahmood, H | 1 |
| Ansari, T | 1 |
| El-Hasani, S | 1 |
| Kluge, S | 1 |
| Hahn, KE | 1 |
| Lund, CH | 1 |
| Gocht, A | 1 |
| Kreymann, G | 1 |
2 other studies available for metronidazole and Air Embolism
| Article | Year |
|---|---|
Pneumomediastinum, stomach wall and hepatic portal vein gas secondary to partial necrosis of the stomach wall.
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; A | 2009 |
[Pylephlebitis with air in the portal vein system. An unusual focus in a patient with sepsis].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anticoagulants; Cefotaxime; Crohn Disease; Diag | 2003 |