metronidazole has been researched along with Aggressive Periodontitis in 76 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Aggressive Periodontitis: Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This randomized, blinded, placebo-controlled clinical trial compared the levels of interferon γ (IFN-γ), prostaglandin E2 (PGE2), and interleukin 6 (IL-6) in the gingival crevicular fluid (GCF) from generalized aggressive periodontitis (GAgP) patients treated with nonsurgical therapy associated or not with amoxicillin/metronidazole adjunctive." | 9.22 | Amoxicillin/metronidazole associated with nonsurgical therapy did not promote additional benefits in immunologic parameters in generalized aggressive periodontitis: A randomized controlled clinical trial. ( Casarin, RC; Casati, MZ; Nociti Júnior, FH; Ribeiro, Édel P; Sallum, EA; Taiete, T, 2016) |
| "The objective of this randomized clinical study was to evaluate the effect of systemic administration of moxifloxacin compared to amoxicillin and metronidazole, combined with non-surgical treatment in patients with generalized aggressive periodontitis (GAgP) in a 6-month follow-up." | 9.20 | Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis. ( Gurgan, CA; Guzeldemir-Akcakanat, E, 2015) |
| " forsythia at baseline showed increased clinical benefits with the adjunctive use of systemic amoxicillin and metronidazole (AMX-MET) during non-surgical treatment of generalized aggressive periodontitis (GAgP)." | 9.19 | Impact of baseline microbiological status on clinical outcomes in generalized aggressive periodontitis patients treated with or without adjunctive amoxicillin and metronidazole: an exploratory analysis from a randomized controlled clinical trial. ( Griffiths, GS; Guerrero, A; Lambertenghi, R; Nibali, L; Ready, D; Suvan, J; Tonetti, MS; Wilson, M, 2014) |
| "To evaluate the short term clinical results of scaling and root planning (SRP) only, SRP combined with amoxicillin (AMX) and metronidazole (MTZ) after supragingival scaling or after SRP in the treatment of aggressive periodontitis (AgP)." | 9.16 | [Short term effect of combined use of amoxicillin and metronidazole at different time of non-surgical periodontal treatment for aggressive periodontitis]. ( Feng, XH; Lu, RF; Meng, HX; Xu, L, 2012) |
| "To evaluate the clinical effects of the adjunctive use of metronidazole (MTZ) and amoxicillin (AMX) in the treatment of generalized aggressive periodontitis (GAgP)." | 9.16 | The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial. ( Duarte, PM; Faveri, M; Feres, M; Fermiano, D; Figueiredo, LC; Mestnik, MJ; Soares, G; Teles, RP, 2012) |
| "The aim of the present study is to assess clinical, microbiologic, and immunologic benefits of amoxicillin/metronidazole (AM) when performing full-mouth ultrasonic debridement (FMUD) in generalized aggressive periodontitis (GAgP) treatment." | 9.16 | The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment. ( Casarin, RC; Casati, MZ; Gonçalves, RB; Nociti, FH; Peloso Ribeiro, ED; Sallum, EA, 2012) |
| "Previously, we showed that systemic metronidazole and amoxicillin significantly improved the outcomes of non-surgical debridement in generalized aggressive periodontitis patients." | 9.15 | Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive periodontitis at initial therapy or re-treatment: a randomized controlled clinical trial. ( Ayob, R; Griffiths, GS; Guerrero, A; Moles, DR; Nibali, L; Suvan, J; Tonetti, MS, 2011) |
| "The aim of this study is to evaluate the effects of metronidazole-amoxicillin combination on clinical and microbiologic parameters in patients with generalized aggressive periodontitis." | 9.14 | Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis. ( Cintan, S; Issever, H; Kantarci, A; Kulekci, G; Topcuoglu, N; Yek, EC, 2010) |
| "The aim of this study was to evaluate the clinical and microbiological effects of scaling and root planing (SRP) alone or combined with metronidazole (MTZ) and amoxicillin (AMX) in the treatment of subjects with generalized aggressive periodontitis (GAgP)." | 9.14 | Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis. ( Duarte, PM; Faveri, M; Feres, M; Figueiredo, LC; Lira, EA; Mestnik, MJ, 2010) |
| "The systemic use of combined amoxicillin and metronidazole (AMX/MET) as an adjunctive treatment to full-mouth scaling and root planing (FMSRP) has been proposed for the treatment of generalized aggressive periodontitis; however, its effectiveness and clinical safety remain to be defined." | 8.88 | Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis. ( Gatto, R; Monaco, A; Petrucci, A; Sgolastra, F, 2012) |
| "The aim of the present study is to evaluate the clinical and microbiologic changes resulting from non-surgical periodontal treatment associated with amoxicillin and metronidazole in individuals with aggressive periodontitis." | 7.78 | Clinical and microbiologic evaluation, by real-time polymerase chain reaction, of non-surgical treatment of aggressive periodontitis associated with amoxicillin and metronidazole. ( De Micheli, G; Hirata, MH; Hirata, RD; Lima Neto, LG; Lotufo, RF; Lourenção, DS; Pannuti, CM; Rodrigues, AS, 2012) |
| "The potential use of an adjunctive therapy of metronidazole plus amoxycillin for the subgingival elimination of Actinobacillus actinomycetemcomitans in periodontitis patients was investigated." | 7.67 | Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis. ( Abbas, F; de Graaff, J; Goené, RJ; Rodenburg, JP; van Winkelhoff, AJ; Winkel, EG, 1989) |
| "3 years) with aggressive periodontitis (AgP; Stage III/IV Grade C periodontitis) were treated by SI and adjunctive amoxicillin and metronidazole and were randomly assigned to Group A: (n = 25) 500 mg antibiotics (AB) 3 times a day for 3 days, followed by placebo 3 times a day for 4 days, or Group B: (n = 25) 500 mg AB 3 times a day for 7 days." | 5.51 | Clinical, microbiological, and immunological effects of 3- or 7-day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade C) periodontitis: A randomized placebo-controlled clinical trial. ( Arweiler, NB; Batori-Andronescu, I; Bora, R; Cosgarea, R; Eick, S; Heumann, C; Jepsen, S; Rosu, A; Sculean, A, 2022) |
| "To assess the clinical and microbiological responses of amoxicillin + metronidazole (AMX + MET) versus clarithromycin (CLM) as adjuncts to one-stage full-mouth ultrasonic debridement (FMUD) in the treatment of generalized aggressive periodontitis (GAgP)." | 5.30 | Two different antibiotic protocols as adjuncts to one-stage full-mouth ultrasonic debridement to treat generalized aggressive periodontitis: A pilot randomized controlled clinical trial. ( Andere, NMRB; Araujo, CF; Casarin, RCV; Castro Dos Santos, NC; de Oliveira, LD; Jardini, MAN; Mathias-Santamaria, IF; Reis, AA; Santamaria, MP, 2019) |
| " In a single-center, randomized, placebo-controlled, and double-masked clinical trial, 80 patients with chronic or aggressive periodontitis were randomized into 2 treatment groups: group A, receiving systemic amoxicillin and metronidazole during the first, nonsurgical phase of periodontal therapy (phase 1), and group B, receiving the antibiotics during the second, surgical phase (phase 2)." | 5.22 | Systemic Biomarkers in 2-Phase Antibiotic Periodontal Treatment: A Randomized Clinical Trial. ( Almaghlouth, A; Cancela, J; Cionca, N; Courvoisier, DS; Giannopoulou, C; Mombelli, A, 2016) |
| "This randomized, blinded, placebo-controlled clinical trial compared the levels of interferon γ (IFN-γ), prostaglandin E2 (PGE2), and interleukin 6 (IL-6) in the gingival crevicular fluid (GCF) from generalized aggressive periodontitis (GAgP) patients treated with nonsurgical therapy associated or not with amoxicillin/metronidazole adjunctive." | 5.22 | Amoxicillin/metronidazole associated with nonsurgical therapy did not promote additional benefits in immunologic parameters in generalized aggressive periodontitis: A randomized controlled clinical trial. ( Casarin, RC; Casati, MZ; Nociti Júnior, FH; Ribeiro, Édel P; Sallum, EA; Taiete, T, 2016) |
| "This study evaluates the antimicrobial susceptibility and composition of subgingival biofilms in generalized aggressive periodontitis (GAP) patients treated using mechanical/antimicrobial therapies, including chlorhexidine (CHX), amoxicillin (AMX) and metronidazole (MET)." | 5.20 | Long-term evaluation of the antimicrobial susceptibility and microbial profile of subgingival biofilms in individuals with aggressive periodontitis. ( Colombo, AP; do Souto, RM; Feres-Filho, EJ; Heller, D; Lourenço, TG; Silva-Senem, MX; Torres, MC; Varela, VM, 2015) |
| " forsythia at baseline showed increased clinical benefits with the adjunctive use of systemic amoxicillin and metronidazole (AMX-MET) during non-surgical treatment of generalized aggressive periodontitis (GAgP)." | 5.19 | Impact of baseline microbiological status on clinical outcomes in generalized aggressive periodontitis patients treated with or without adjunctive amoxicillin and metronidazole: an exploratory analysis from a randomized controlled clinical trial. ( Griffiths, GS; Guerrero, A; Lambertenghi, R; Nibali, L; Ready, D; Suvan, J; Tonetti, MS; Wilson, M, 2014) |
| " Aggressive periodontitis subjects were randomly assigned to either scaling and root planing (SRP) alone or SRP plus systemic amoxicillin (500 mg) and metronidazole (400 mg) 3 times a day for 14 days." | 5.16 | Effects of periodontal therapy on GCF cytokines in generalized aggressive periodontitis subjects. ( de Faveri, M; de Lima Oliveira, AP; Feres, M; Gursky, LC; Haffajee, AD; Mestnik, MJ; Socransky, SS; Teles, RP, 2012) |
| "The present investigation aimed to analyse clinical and microbiological effects of systemic administration of metronidazole and amoxicillin combined with the One-Stage-Full-Mouth-Disinfection protocol (OSFMD) in generalized aggressive periodontitis patients (G-AgP)." | 5.16 | Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial. ( Aimetti, M; Carnevale, G; Guzzi, N; Romano, F, 2012) |
| "The aim of the present study is to assess clinical, microbiologic, and immunologic benefits of amoxicillin/metronidazole (AM) when performing full-mouth ultrasonic debridement (FMUD) in generalized aggressive periodontitis (GAgP) treatment." | 5.16 | The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment. ( Casarin, RC; Casati, MZ; Gonçalves, RB; Nociti, FH; Peloso Ribeiro, ED; Sallum, EA, 2012) |
| "To evaluate the clinical effects of the adjunctive use of metronidazole (MTZ) and amoxicillin (AMX) in the treatment of generalized aggressive periodontitis (GAgP)." | 5.16 | The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial. ( Duarte, PM; Faveri, M; Feres, M; Fermiano, D; Figueiredo, LC; Mestnik, MJ; Soares, G; Teles, RP, 2012) |
| "To assess the clinical benefit of either metronidazole and amoxicillin or doxycycline administered immediately after completion of full-mouth scaling and root planing (FRP) for treatment of generalized aggressive periodontitis." | 5.15 | Analysis of clinical results of systemic antimicrobials combined with nonsurgical periodontal treatment for generalized aggressive periodontitis: a pilot study. ( Aslan, M; Baltacioglu, E; Saraç, Ö; Saybak, A; Yuva, P, 2011) |
| "To compare the effects of systemic amoxicillin (AMX) plus metronidazole (MET) or placebos combined with anti-infective mechanical debridement on the sub-gingival microbiota of generalized aggressive periodontitis (GAP)." | 5.15 | Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: a 6-month RCT. ( Colombo, AP; Feres-Filho, EJ; Heller, D; Silva-Senem, MX; Torres, MC; Varela, VM, 2011) |
| "The aim of this study was to evaluate the clinical and microbiological effects of scaling and root planing (SRP) alone or combined with metronidazole (MTZ) and amoxicillin (AMX) in the treatment of subjects with generalized aggressive periodontitis (GAgP)." | 5.14 | Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis. ( Duarte, PM; Faveri, M; Feres, M; Figueiredo, LC; Lira, EA; Mestnik, MJ, 2010) |
| "The aim of this study is to evaluate the effects of metronidazole-amoxicillin combination on clinical and microbiologic parameters in patients with generalized aggressive periodontitis." | 5.14 | Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis. ( Cintan, S; Issever, H; Kantarci, A; Kulekci, G; Topcuoglu, N; Yek, EC, 2010) |
| "Eighty patients with chronic or aggressive periodontitis received periodontal treatment supplemented with 375 mg amoxicillin plus 500 mg metronidazole, three times daily for 7 days." | 3.85 | Microbiologic Response to Periodontal Therapy and Multivariable Prediction of Clinical Outcome. ( Almaghlouth, A; Cancela, J; Cionca, N; Courvoisier, DS; Giannopoulou, C; Mombelli, A, 2017) |
| "The aim of the present study is to evaluate the clinical and microbiologic changes resulting from non-surgical periodontal treatment associated with amoxicillin and metronidazole in individuals with aggressive periodontitis." | 3.78 | Clinical and microbiologic evaluation, by real-time polymerase chain reaction, of non-surgical treatment of aggressive periodontitis associated with amoxicillin and metronidazole. ( De Micheli, G; Hirata, MH; Hirata, RD; Lima Neto, LG; Lotufo, RF; Lourenção, DS; Pannuti, CM; Rodrigues, AS, 2012) |
| "The potential use of an adjunctive therapy of metronidazole plus amoxycillin for the subgingival elimination of Actinobacillus actinomycetemcomitans in periodontitis patients was investigated." | 3.67 | Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis. ( Abbas, F; de Graaff, J; Goené, RJ; Rodenburg, JP; van Winkelhoff, AJ; Winkel, EG, 1989) |
| "Twenty-five localized juvenile periodontitis (LJP) patients from a Brazilian population were randomly allocated into an experimental group receiving mechanical treatment and antibiotics, and a control group receiving mechanical treatment and placebo." | 2.69 | Clinical and microbiological effects of adjunctive antibiotics in treatment of localized juvenile periodontitis. A controlled clinical trial. ( Beldi, MI; Bellini, HT; Campedelli, F; Gjermo, P; Lana, M; Loureiro, CA; Preus, HR; Rams, TE; Tinoco, EM; Tinoco, NM, 1998) |
| "Metronidazole has important interactions with alcohol, disulfiram and warfarin and there are contraindications to its use." | 2.37 | Metronidazole: its use in clinical dentistry. ( Mitchell, DA, 1984) |
| "Eleven studies were performed in chronic periodontitis patients and six in aggressive periodontitis patients." | 1.51 | No evidence to support benefit of 14-day courses of amoxicillin-plus-metronidazole as adjunct to non-surgical periodontal treatment at three months. ( Huck, O; Martín-Cabezas, R, 2019) |
| "Localized aggressive periodontitis is a distinct entity of periodontal disease and is characterized by deep vertical bony defects that typically affect the first molars and incisors of young patients." | 1.35 | Minimally invasive flap surgery and enamel matrix derivative in the treatment of localized aggressive periodontitis: case report. ( Bernimoulin, JP; Friedmann, A; Kaner, D; Kleber, BM, 2009) |
| "Prepubertal periodontitis affects both primary and permanent dentition." | 1.30 | Subgingival microflora and treatment in prepubertal periodontitis associated with chronic idiopathic neutropenia. ( Kamma, JJ; Lygidakis, NA; Nakou, M, 1998) |
| "The treatment of localized juvenile periodontitis has been previously described in the literature, utilizing primarily a long-term (2 to 6 week) antibiotic regimen, notably tetracycline." | 1.29 | Localized prepubertal periodontitis--nonsurgical treatment of an adolescent patient: a case report. ( Epstein, SR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.63) | 18.7374 |
| 1990's | 10 (13.16) | 18.2507 |
| 2000's | 10 (13.16) | 29.6817 |
| 2010's | 51 (67.11) | 24.3611 |
| 2020's | 3 (3.95) | 2.80 |
| Authors | Studies |
|---|---|
| Cosgarea, R | 1 |
| Jepsen, S | 1 |
| Heumann, C | 2 |
| Batori-Andronescu, I | 1 |
| Rosu, A | 1 |
| Bora, R | 1 |
| Arweiler, NB | 4 |
| Eick, S | 1 |
| Sculean, A | 5 |
| Ardila, CM | 1 |
| Flórez-Flórez, J | 1 |
| Castañeda-Parra, LD | 1 |
| Guzmán, IC | 1 |
| Bedoya-García, JA | 1 |
| Feng, XH | 2 |
| Lu, RF | 2 |
| Zhang, L | 1 |
| Xu, L | 2 |
| Chen, ZB | 1 |
| Meng, HX | 2 |
| Usin, MM | 1 |
| Tabares, SM | 1 |
| Menso, J | 1 |
| de Albera, ER | 1 |
| Sembaj, A | 1 |
| Burgess, DK | 1 |
| Huang, H | 3 |
| Harrison, P | 3 |
| Kompotiati, T | 1 |
| Aukhil, I | 5 |
| Shaddox, LM | 5 |
| Mombelli, A | 3 |
| Almaghlouth, A | 3 |
| Cionca, N | 3 |
| Cancela, J | 2 |
| Courvoisier, DS | 2 |
| Giannopoulou, C | 2 |
| Rebeis, ES | 2 |
| Albuquerque-Souza, E | 2 |
| Paulino da Silva, M | 1 |
| Giudicissi, M | 1 |
| Mayer, MPA | 2 |
| Saraiva, L | 2 |
| Aral, K | 1 |
| Aral, CA | 1 |
| Kapila, Y | 1 |
| Martins, ES | 1 |
| César-Neto, JB | 1 |
| Holzhausen, M | 1 |
| Pannuti, CM | 2 |
| Martín-Cabezas, R | 1 |
| Huck, O | 1 |
| Araujo, CF | 1 |
| Andere, NMRB | 1 |
| Castro Dos Santos, NC | 1 |
| Mathias-Santamaria, IF | 1 |
| Reis, AA | 1 |
| de Oliveira, LD | 1 |
| Jardini, MAN | 1 |
| Casarin, RCV | 1 |
| Santamaria, MP | 1 |
| Gonçalves, PF | 2 |
| McAninley, S | 1 |
| Alfant, B | 1 |
| Walker, C | 2 |
| Vovk, A | 2 |
| Allin, N | 1 |
| Hou, W | 1 |
| Wallet, SM | 2 |
| Pietruska, M | 3 |
| Skurska, A | 3 |
| Dolińska, E | 3 |
| Pietruski, JK | 2 |
| Bläs, M | 1 |
| Auschill, TM | 2 |
| Lira, EA | 2 |
| Ramiro, FS | 1 |
| Chiarelli, FM | 1 |
| Dias, RR | 1 |
| Feres, M | 5 |
| Figueiredo, LC | 4 |
| Faveri, M | 4 |
| Pietruski, J | 1 |
| Preus, HR | 2 |
| Scheie, AA | 1 |
| Baelum, V | 1 |
| Zandbergen, D | 1 |
| Slot, DE | 1 |
| Cobb, CM | 1 |
| Van der Weijden, FA | 1 |
| Guerrero, A | 2 |
| Nibali, L | 2 |
| Lambertenghi, R | 1 |
| Ready, D | 1 |
| Suvan, J | 2 |
| Griffiths, GS | 2 |
| Wilson, M | 1 |
| Tonetti, MS | 2 |
| Merchant, SN | 1 |
| Kalash, D | 1 |
| Hovencamp, N | 1 |
| Zapert, E | 1 |
| Bidwell, J | 1 |
| Varnado, P | 1 |
| Gillam, DG | 1 |
| Turner, W | 1 |
| Keestra, JA | 1 |
| Grosjean, I | 1 |
| Coucke, W | 1 |
| Quirynen, M | 1 |
| Teughels, W | 1 |
| Kolakovic, M | 1 |
| Held, U | 1 |
| Schmidlin, PR | 1 |
| Sahrmann, P | 1 |
| Dymicka, V | 1 |
| Kemona, H | 1 |
| Milewsk, R | 1 |
| Guzeldemir-Akcakanat, E | 1 |
| Gurgan, CA | 1 |
| Siqueira, SJ | 1 |
| Ribeiro, FV | 1 |
| Villalpando, KT | 1 |
| Cirano, FR | 1 |
| Pimentel, SP | 1 |
| Rabelo, CC | 1 |
| Gonçalves, C | 1 |
| Tu, YK | 1 |
| Chambrone, L | 1 |
| Lourenço, TG | 1 |
| Heller, D | 4 |
| do Souto, RM | 1 |
| Silva-Senem, MX | 4 |
| Varela, VM | 4 |
| Torres, MC | 4 |
| Feres-Filho, EJ | 4 |
| Colombo, AP | 4 |
| Taiete, T | 1 |
| Casati, MZ | 2 |
| Ribeiro, Édel P | 1 |
| Sallum, EA | 2 |
| Nociti Júnior, FH | 1 |
| Casarin, RC | 2 |
| Agrawal, N | 1 |
| Kallury, A | 1 |
| Khurana, R | 1 |
| Jain, V | 1 |
| Agarwal, K | 1 |
| Emrani, J | 1 |
| Chee, W | 1 |
| Slots, J | 2 |
| Johnson, JD | 1 |
| Chen, R | 1 |
| Lenton, PA | 1 |
| Zhang, G | 1 |
| Hinrichs, JE | 1 |
| Rudney, JD | 1 |
| Machtei, EE | 1 |
| Younis, MN | 1 |
| Kaner, D | 2 |
| Bernimoulin, JP | 2 |
| Kleber, BM | 2 |
| Friedmann, A | 2 |
| Steiger, J | 1 |
| Zeevi, A | 1 |
| Bhola, M | 1 |
| Yek, EC | 1 |
| Cintan, S | 1 |
| Topcuoglu, N | 1 |
| Kulekci, G | 1 |
| Issever, H | 1 |
| Kantarci, A | 1 |
| Buchmann, R | 1 |
| Conrads, G | 1 |
| Mestnik, MJ | 3 |
| Duarte, PM | 2 |
| Leininger, M | 1 |
| Tenenbaum, H | 1 |
| Davideau, JL | 1 |
| Zhang, X | 1 |
| Zhang, JC | 1 |
| Ayob, R | 1 |
| Moles, DR | 1 |
| Zafiropoulos, GG | 1 |
| di Prisco, MO | 1 |
| Deli, G | 1 |
| Hoffmann, O | 1 |
| Kasaj, A | 1 |
| Tang, XL | 1 |
| Lin, L | 1 |
| Décaillet, F | 1 |
| Wick, P | 1 |
| Dietrich, T | 1 |
| Baltacioglu, E | 1 |
| Aslan, M | 1 |
| Saraç, Ö | 1 |
| Saybak, A | 1 |
| Yuva, P | 1 |
| Sgolastra, F | 1 |
| Petrucci, A | 1 |
| Gatto, R | 1 |
| Monaco, A | 1 |
| Rodrigues, AS | 1 |
| Lourenção, DS | 1 |
| Lima Neto, LG | 1 |
| Hirata, RD | 1 |
| Hirata, MH | 1 |
| Lotufo, RF | 1 |
| De Micheli, G | 1 |
| de Lima Oliveira, AP | 1 |
| de Faveri, M | 1 |
| Gursky, LC | 1 |
| Haffajee, AD | 1 |
| Socransky, SS | 1 |
| Teles, RP | 2 |
| Aimetti, M | 1 |
| Romano, F | 1 |
| Guzzi, N | 1 |
| Carnevale, G | 1 |
| Peloso Ribeiro, ED | 1 |
| Nociti, FH | 1 |
| Gonçalves, RB | 1 |
| Soares, G | 1 |
| Fermiano, D | 1 |
| Beliveau, D | 1 |
| Magnusson, I | 1 |
| Bidwell, JA | 1 |
| Zapert, EF | 1 |
| Seremidi, K | 1 |
| Gizani, S | 1 |
| Madianos, P | 1 |
| Karpinia, K | 1 |
| Mitchell, DA | 1 |
| Saxén, L | 1 |
| Asikainen, S | 1 |
| Epstein, SR | 1 |
| Efeoğlu, E | 1 |
| Sandalli, P | 1 |
| Sixou, JL | 1 |
| Robert, JC | 1 |
| Bonnaure-Mallet, M | 1 |
| Kamma, JJ | 1 |
| Lygidakis, NA | 1 |
| Nakou, M | 1 |
| Tinoco, EM | 1 |
| Beldi, MI | 1 |
| Campedelli, F | 1 |
| Lana, M | 1 |
| Loureiro, CA | 1 |
| Bellini, HT | 1 |
| Rams, TE | 2 |
| Tinoco, NM | 1 |
| Gjermo, P | 1 |
| Reichert, S | 1 |
| Riemann, D | 1 |
| Plaschka, B | 1 |
| Machulla, HK | 1 |
| De Vree, H | 1 |
| Steenackers, K | 1 |
| De Boever, JA | 1 |
| Worch, KP | 1 |
| Listgarten, MA | 2 |
| Korostoff, JM | 1 |
| Eickholz, P | 1 |
| Kugel, B | 1 |
| Pohl, S | 1 |
| Näher, H | 1 |
| Staehle, HJ | 1 |
| Bodur, A | 1 |
| Bodur, H | 1 |
| Bal, B | 1 |
| Baloş, K | 1 |
| Khatiblou, FA | 1 |
| Donly, KJ | 1 |
| Ashkenazi, M | 1 |
| Feik, D | 1 |
| van Winkelhoff, AJ | 1 |
| Rodenburg, JP | 1 |
| Goené, RJ | 1 |
| Abbas, F | 1 |
| Winkel, EG | 1 |
| de Graaff, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery[NCT05027893] | 157 participants (Actual) | Interventional | 2019-06-07 | Active, not recruiting | |||
| Mechanisms and Treatment Response of Aggressive Periodontitis in Children: Aberrant Immunological Phenotypes/Functions in the Progression of AgP[NCT01330719] | 514 participants (Actual) | Interventional | 2006-12-31 | Active, not recruiting | |||
| Full-mouth Periodontal Debridement Associated With Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis: Randomized Controlled Clinical Trial[NCT02969928] | Phase 2/Phase 3 | 46 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| Evaluation of the Local Effect of Nonsurgical Periodontal Treatment of Generalized Aggressive Periodontitis Associated or Not With Systemic Antibiotics and Photodynamic Therapy.: a Randomized Clinical Trial[NCT03142776] | 60 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Clinical Effects of Doxycycline in the Treatment of Aggressive Periodontitis: Comparative Clinical Study[NCT03727620] | Phase 1/Phase 2 | 24 participants (Actual) | Interventional | 2014-01-06 | Completed | ||
| Impact of Different Dosages and Time of Administration of Metronidazole and Amoxicillin in the Treatment of Generalized Chronic Periodontitis: A Randomized Clinical Trial[NCT02735395] | Phase 4 | 110 participants (Actual) | Interventional | 2011-07-31 | Active, not recruiting | ||
| Pharmacokinetic Considerations and Dosing Strategies of Amoxicillin and Metronidazole or Azithromycin as Adjunct to Non-surgical Periodontal Therapy. A Randomized,6-month, Parallel-group, Clinical Trial.[NCT04669717] | Phase 4 | 45 participants (Anticipated) | Interventional | 2021-09-01 | Recruiting | ||
| Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing on Clinical, Microbiological and Systemic Response[NCT02197260] | Phase 4 | 80 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| Effects of a Toothpaste Containing 0.3% Triclosan in the Maintenance Phase of Peri-implantitis Treatment.[NCT03191721] | Phase 3 | 102 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Influence of Moment of Systemic Metronidazole and Amoxicillin Administration in the Treatment of Chronic Periodontitis: a Randomized Clinical Trial.[NCT02954393] | 180 participants (Anticipated) | Interventional | 2015-05-31 | Active, not recruiting | |||
| Clinical Evaluation of Systemic Moxifloxacin Compared to Amoxicillin Plus Metronidazole Adjunct to Non-surgical Treatment in Generalized Aggressive Periodontitis: A Randomized Clinical Trial[NCT02223702] | Phase 4 | 39 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| Effect of Non Surgical Therapy on Calprotectin and Periostin Levels in Patients With Periodontitis and Cardiovascular Diseases - An Interventional Study[NCT05618743] | 45 participants (Anticipated) | Interventional | 2021-06-30 | Recruiting | |||
| Evaluation of Gingival Crevicular Fluid Interleukin-1β and Interleukin-17 Levels and Periodontal Pathogens After Full-Mouth Disinfection Initial Periodontal Treatment in Generalized Aggressive Periodontitis Patients[NCT02466646] | Phase 4 | 42 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Single Arm Pilot Study of Antimicrobial Treatment of Active Rheumatoid Arthritis Associated With Manifest Periodontitis (Translated From German: Anti-mikrobielle Behandlung Der Aktiven Rheumatoiden Arthritis Bei Manifester Parodontitis - Eine Unkontrollie[NCT02096120] | 8 participants (Actual) | Observational | 2014-02-28 | Completed | |||
| Clarithromycin as Adjuvant to Periodontal Debridement in the Treatment of Generalized Aggressive Periodontitis: Randomized Clinical Trial[NCT02829983] | 40 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Observational Study on Cytokine Production by Leukocytes of Papillon-Lefèvre Syndrome Patients and Healthy Probands in Whole Blood Cultures[NCT01116934] | 17 participants (Actual) | Observational | 2006-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients will be instructed to fill a self-report form about any possible adverse effects in order to help evaluate their adherence to the systemic antimicrobial regimen. (NCT02969928)
Timeframe: One week post treatment
| Intervention | Participants (Count of Participants) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Headache | Stomach pain | Nausea/vomiting | Metallic taste | Diarrhea/abdominal pain | Drowsiness | Itching | Skin wounds | None | |
| Amoxicillin and Metronidazole | 1 | 4 | 3 | 7 | 3 | 2 | 1 | 0 | 5 |
| Clarithromycin | 2 | 3 | 6 | 13 | 3 | 3 | 0 | 0 | 5 |
Evaluate the difference between baseline and 6 months BoP measures. (NCT02969928)
Timeframe: Baseline, 3 and 6 months
| Intervention | % of sites with bleeding on probe (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Amoxicillin and Metronidazole | 53.4 | 30.2 | 27.3 |
| Clarithromycin | 43.7 | 24.8 | 23.3 |
Evaluate the difference between baseline and 6 months CAL measures. (NCT02969928)
Timeframe: Baseline, 3 and 6 months
| Intervention | mm (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Amoxicillin and Metronidazole | 3.69 | 2.4 | 3 |
| Clarithromycin | 3.62 | 3 | 3 |
Evaluate the difference between baseline and 6 months PB measures. (NCT02969928)
Timeframe: Baseline, 3 and 6 months
| Intervention | mm (Mean) | ||
|---|---|---|---|
| Baseline | 3 months | 6 months | |
| Amoxicillin and Metronidazole | 3.44 | 2.5 | 2.6 |
| Clarithromycin | 3.41 | 2.7 | 2.7 |
After 7 days of periodontal treatment, patients will be asked to return any medication not taken and/or the empty bottles. The number of pills not taken by the subject will be documented in order to evaluate compliance. (NCT02969928)
Timeframe: One week post treatment
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| # of patients that did not take ≥1 pills | # of patients that interrupted the drug intake | |
| Amoxicillin and Metronidazole | 3 | 2 |
| Clarithromycin | 4 | 0 |
Attachment loss were recorded at baseline, 1st, 3rd and 6th months as millimeters. The data were compared among and between groups. (NCT02223702)
Timeframe: 6-months
| Intervention | mm (Mean) | |||
|---|---|---|---|---|
| Baseline | 1st month | 3rd month | 6th month | |
| Amoxicillin+Metronidazole | 5.03 | 4.37 | 4.41 | 4.33 |
| Moxifloxacin | 4.94 | 4.14 | 3.98 | 4.30 |
We measured the probing depth at baseline, 1st, 3rd and 6th months. The changes were evaluated among and between groups. (NCT02223702)
Timeframe: 6-months
| Intervention | mm (Mean) | |||
|---|---|---|---|---|
| Baseline | 1st month | 3rd month | 6th month | |
| Amoxicillin+Metronidazole | 4.57 | 3.12 | 3.11 | 3.15 |
| Moxifloxacin | 4.18 | 2.91 | 2.79 | 3.01 |
Possible score for BOP range from %0 (no sites with bleeding on probing) to %100 (all sites with bleeding on probing). Higher scores mean worse outcome. (NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | percentage of BOP positive sites (Mean) | ||
|---|---|---|---|
| Baseline Bleeding on Probing (BOP) | 3rd month BOP | 6th month BOP | |
| Conventional IPT | 89.28 | 54.43 | 60.19 |
| Full-mouth Disinfection IPT | 78.30 | 38.87 | 42.78 |
| Full-mouth IPT | 85.77 | 48.90 | 49.74 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | mm (Mean) | ||
|---|---|---|---|
| Baseline Clinical Attachment Level (CAL) | 3rd month CAL | 6th month CAL | |
| Conventional IPT | 5.67 | 4.94 | 5.25 |
| Full-mouth Disinfection IPT | 5.20 | 4.54 | 4.51 |
| Full-mouth IPT | 5.79 | 5.10 | 5.13 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | Picogram (Mean) | |||||
|---|---|---|---|---|---|---|
| Baseline Interleukin-1β | 3rd month IL-1β | 6th month IL-1β | Baseline Interleukin-17 | 3rd month IL-17 | 6th month IL-17 | |
| Conventional IPT | 2.27 | 2.11 | 1.90 | 19.91 | 21.02 | 19.27 |
| Full-mouth Disinfection IPT | 2.53 | 2.07 | 2.11 | 18.53 | 21.07 | 20.05 |
| Full-mouth IPT | 2.15 | 2.06 | 1.96 | 19.67 | 19.76 | 18.46 |
Possible score for Gingival Index range from 0 (healthy gingiva) to 3 (severe gingivitis with bleeding). Higher scores mean worse outcome (NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Baseline GI | 3rd month GI | 6th month GI | |
| Conventional IPT | 1.80 | 1.15 | 1.29 |
| Full-mouth Disinfection IPT | 1.61 | 1.17 | 1.20 |
| Full-mouth IPT | 1.74 | 1.24 | 1.21 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline A. actinomycetemcomitans level | 3rd months A. actinomycetemcomitans level | 6th month A. actinomycetemcomitans level | |
| Conventional IPT | 3.84 | 3.73 | 3.59 |
| Full-mouth Disinfection IPT | 3.65 | 3.27 | 2.92 |
| Full-mouth IPT | 3.63 | 3.47 | 3.47 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline C. rectus level | 3rd month C. rectus level | 6th month C. rectus level | |
| Conventional IPT | 6.19 | 5.01 | 4.99 |
| Full-mouth Disinfection IPT | 5.95 | 4.63 | 4.64 |
| Full-mouth IPT | 5.99 | 5.25 | 5.03 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline F. nucleatum level | 3rd month F. nucleatum level | 6th month F. nucleatum level | |
| Conventional IPT | 4.78 | 3.99 | 3.84 |
| Full-mouth Disinfection IPT | 4.67 | 3.84 | 3.73 |
| Full-mouth IPT | 4.66 | 4.42 | 4.17 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline P. micra level | 3rd month P. micra level | 6th month P. micra level | |
| Conventional IPT | 4.86 | 4.34 | 4.30 |
| Full-mouth Disinfection IPT | 4.96 | 4.22 | 4.28 |
| Full-mouth IPT | 4.70 | 4.51 | 4.43 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline P. gingivalis level | 3rd months P. gingivalis level | 6th month P. gingivalis level | |
| Conventional IPT | 5.50 | 3.60 | 4.00 |
| Full-mouth Disinfection IPT | 4.64 | 2.90 | 3.25 |
| Full-mouth IPT | 5.47 | 3.74 | 3.84 |
(NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | log10(cells/ml) (Mean) | ||
|---|---|---|---|
| Baseline P. intermedia level | 3rd month P. intermedia level | 6th month P. intermedia level | |
| Conventional IPT | 5.51 | 3.70 | 4.14 |
| Full-mouth Disinfection IPT | 4.24 | 2.73 | 2.98 |
| Full-mouth IPT | 4.84 | 3.81 | 3.46 |
Possible scores for Plaque Index range from 0 (no plaque) to 3 (visible plaque all around the tooth). Higher scores mean a worse outcome (NCT02466646)
Timeframe: Baseline, 3 and 6 months after initial periodontal treatment
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Baseline PI | 3rd month PI | 6th month PI | |
| Conventional IPT | 1.76 | 0.69 | 0.77 |
| Full-mouth Disinfection IPT | 1.51 | 0.67 | 0.72 |
| Full-mouth IPT | 1.62 | 0.84 | 0.82 |
(NCT02466646)
Timeframe: 6 months after initial periodontal treatment
| Intervention | mm (Mean) | |
|---|---|---|
| Baseline Probing Depth (PD) | 6th month PD | |
| Conventional IPT | 4.80 | 3.40 |
| Full-mouth Disinfection IPT | 4.55 | 2.71 |
| Full-mouth IPT | 4.90 | 3.04 |
Distance from bottom of pocket to the cement-enamel junction (CEJ). (NCT02829983)
Timeframe: 6 months
| Intervention | milimeter (Mean) |
|---|---|
| Clarithromycin Group | 2.71 |
| Placebo Group | 3.03 |
Distance from the bottom of sulcus/pocket to gingival margin (NCT02829983)
Timeframe: 6 months
| Intervention | milimeter (Mean) |
|---|---|
| Clarithromycin Group | 2.53 |
| Placebo Group | 2.86 |
Concentrations of IL-8, IL-6, IP-10, interferon (IFN)-gamma, and IL-1 beta, in plasma/RPMI samples were determined by enzyme linked immunosorbent assay (ELISA) according to the manufacturers' instructions (NCT01116934)
Timeframe: 2006
| Intervention | pg/ml (Median) | ||||
|---|---|---|---|---|---|
| interleukin-1 beta | interleukin-6 | interferon-inducible protein-10 | interferon gamma | interleukin-8 | |
| Healthy Controls | 896.21 | 45734 | 11563 | 3317.4 | 44390 |
| Papillon-Lefèvre Syndrome (PLS) Patients | 1100.00 | 65559 | 12902.5 | 3704.5 | 50520 |
8 reviews available for metronidazole and Aggressive Periodontitis
| Article | Year |
|---|---|
Non-surgical periodontal therapy with systemic antibiotics in patients with untreated aggressive periodontitis: a systematic review and meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Humans; Met | 2015 |
An estimate of pocket closure and avoided needs of surgery after scaling and root planing with systemic antibiotics: a systematic review.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Chronic Periodontitis; Combined Modali | 2014 |
Systemic antibiotics in the treatment of aggressive periodontitis. A systematic review and a Bayesian Network meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bayes Theorem; Combined Modality Thera | 2015 |
[Efficient, minimally invasive periodontal therapy. An evidence based treatment concept].
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2011 |
Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Dental Scaling; | 2012 |
Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Dental Scaling; | 2012 |
Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Dental Scaling; | 2012 |
Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Dental Scaling; | 2012 |
Rationale for use of antibiotics in periodontics.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial | 2002 |
Metronidazole: its use in clinical dentistry.
Topics: Aggressive Periodontitis; Bacteria, Anaerobic; Drug Interactions; Gingivitis; Humans; Kinetics; Metr | 1984 |
Juvenile periodontitis: a review of pathogenesis, diagnosis and treatment.
Topics: Adolescent; Aggressive Periodontitis; Bone Transplantation; Child; Humans; Metronidazole; Penicillin | 1992 |
34 trials available for metronidazole and Aggressive Periodontitis
| Article | Year |
|---|---|
Clinical, microbiological, and immunological effects of 3- or 7-day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade C) periodontitis: A randomized placebo-controlled clinical trial.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Dental Scaling; Humans; Metronidazole | 2022 |
Moxifloxacin versus amoxicillin plus metronidazole as adjunctive therapy for generalized aggressive periodontitis: a pilot randomized controlled clinical trial.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Dental Scaling; Humans; Metronidazole; | 2020 |
Non-Surgical Therapy Reduces Presence of JP2 Clone in Localized Aggressive Periodontitis.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Ant | 2017 |
Two different antibiotic protocols as adjuncts to one-stage full-mouth ultrasonic debridement to treat generalized aggressive periodontitis: A pilot randomized controlled clinical trial.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; | 2019 |
Periodontal treatment reduces matrix metalloproteinase levels in localized aggressive periodontitis.
Topics: Adolescent; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Black or African American; | 2013 |
LPS-induced inflammatory response after therapy of aggressive periodontitis.
Topics: Adolescent; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Chemokine CCL2; Chemokine | 2013 |
Nonsurgical treatment of aggressive periodontitis with photodynamic therapy or systemic antibiotics. Three-month results of a randomized, prospective, controlled clinical study.
Topics: Administration, Oral; Adult; Aggressive Periodontitis; Amoxicillin; Analysis of Variance; Anti-Bacte | 2013 |
Reduction in prevalence of Archaea after periodontal therapy in subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Archaea; Combined Modality Ther | 2013 |
Six-month results following treatment of aggressive periodontitis with antimicrobial photodynamic therapy or amoxicillin and metronidazole.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Dental Scaling; Female; Humans; | 2014 |
Impact of baseline microbiological status on clinical outcomes in generalized aggressive periodontitis patients treated with or without adjunctive amoxicillin and metronidazole: an exploratory analysis from a randomized controlled clinical trial.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; | 2014 |
Localized aggressive periodontitis treatment response in primary and permanent dentitions.
Topics: Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Child; Child, Presc | 2014 |
Effect of nonsurgical periodontal treatment in conjunction with either systemic administration of amoxicillin and metronidazole or additional photodynamic therapy on the concentration of matrix metalloproteinases 8 and 9 in gingival crevicular fluid in pa
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Combined Modali | 2015 |
Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Drug Therapy, Combination; Fema | 2015 |
Long-term evaluation of the antimicrobial susceptibility and microbial profile of subgingival biofilms in individuals with aggressive periodontitis.
Topics: Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Biofilms; | 2015 |
Amoxicillin/metronidazole associated with nonsurgical therapy did not promote additional benefits in immunologic parameters in generalized aggressive periodontitis: A randomized controlled clinical trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Combined | 2016 |
Systemic Biomarkers in 2-Phase Antibiotic Periodontal Treatment: A Randomized Clinical Trial.
Topics: Acute-Phase Proteins; Adult; Aged; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bio | 2016 |
Systemic Biomarkers in 2-Phase Antibiotic Periodontal Treatment: A Randomized Clinical Trial.
Topics: Acute-Phase Proteins; Adult; Aged; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bio | 2016 |
Systemic Biomarkers in 2-Phase Antibiotic Periodontal Treatment: A Randomized Clinical Trial.
Topics: Acute-Phase Proteins; Adult; Aged; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bio | 2016 |
Systemic Biomarkers in 2-Phase Antibiotic Periodontal Treatment: A Randomized Clinical Trial.
Topics: Acute-Phase Proteins; Adult; Aged; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bio | 2016 |
The use of 2 antibiotic regimens in aggressive periodontitis: comparison of changes in clinical parameters and gingival crevicular fluid biomarkers.
Topics: Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Biomarkers; Dental | 2008 |
Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Ant | 2010 |
Short-term effects of systemic antibiotics during periodontal healing.
Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; A | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Bacteria; Combined Modality The | 2010 |
Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive periodontitis at initial therapy or re-treatment: a randomized controlled clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Analysis of Variance | 2011 |
Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: a 6-month randomized controlled trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Combined Modality Therapy; Dent | 2011 |
Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: a 6-month RCT.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Ant | 2011 |
[Efficient, minimally invasive periodontal therapy. An evidence based treatment concept].
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2011 |
Calprotectin levels in gingival crevicular fluid predict disease activity in patients treated for generalized aggressive periodontitis.
Topics: Administration, Topical; Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-I | 2011 |
Analysis of clinical results of systemic antimicrobials combined with nonsurgical periodontal treatment for generalized aggressive periodontitis: a pilot study.
Topics: Administration, Oral; Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Chi-Squar | 2011 |
Effects of periodontal therapy on GCF cytokines in generalized aggressive periodontitis subjects.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Analysis of Variance; Anti-Bacterial Agents; Cytokines | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxic | 2012 |
The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial | 2012 |
The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Combined Modality Therapy; Dent | 2012 |
The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Combined Modality Therapy; Dent | 2012 |
The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Combined Modality Therapy; Dent | 2012 |
The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Combined Modality Therapy; Dent | 2012 |
Clinical and microbiological effects of systemic antimicrobials combined to an anti-infective mechanical debridement for the management of aggressive periodontitis: a 12-month randomized controlled trial.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective | 2013 |
[Short term effect of combined use of amoxicillin and metronidazole at different time of non-surgical periodontal treatment for aggressive periodontitis].
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Combined | 2012 |
Metronidazole in the treatment of localized juvenile periodontitis.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Bone Lo | 1993 |
Clinical and microbiological effects of adjunctive antibiotics in treatment of localized juvenile periodontitis. A controlled clinical trial.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Process | 1998 |
35 other studies available for metronidazole and Aggressive Periodontitis
| Article | Year |
|---|---|
[Effect of systemic use of amoxicillin and metronidazole during mechanical therapy on the periodontal microorganisms in subgingival plaque and saliva of patients with aggressive periodontitis].
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Dental Plaque; Dental Scaling; Humans; | 2020 |
Generalized aggressive periodontitis: microbiological composition and clinical parameters in non-surgical therapy.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial | 2016 |
Microbiologic Response to Periodontal Therapy and Multivariable Prediction of Clinical Outcome.
Topics: Adult; Aged; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Infe | 2017 |
Effect of periodontal treatment on Aggregatibacter actinomycetemcomitans colonization and serum IgG levels against A. actinomycetemcomitans serotypes and Omp29 of aggressive periodontitis patients.
Topics: Adolescent; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Ant | 2019 |
Six-month clinical outcomes of non-surgical periodontal treatment with antibiotics on apoptosis markers in aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; A | 2019 |
One-year follow-up of the immune profile in serum and selected sites of generalized and localized aggressive periodontitis.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Cell Movement; Cytokines; Gingival Cre | 2019 |
No evidence to support benefit of 14-day courses of amoxicillin-plus-metronidazole as adjunct to non-surgical periodontal treatment at three months.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Chronic Periodontitis; Humans; Metroni | 2019 |
Letter to the editor: Re: The clinical effect of scaling and root planing and the concomitant administration of systemic amoxicillin and metronidazole: a systematic review; Re: Effectiveness of systemic amoxicillin/metronidazole as adjunctive therapy to s
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Periodo | 2014 |
Letter to the editor: Authors' response.
Topics: Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Periodo | 2014 |
Antibiotics in the treatment of periodontal disease: a guide for the general dental practitioner.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Biofilms; Chronic Periodontitis | 2014 |
Maintenance periodontal therapy after systemic antibiotic and regenerative therapy of generalized aggressive periodontitis. A case report with 10-year follow-up.
Topics: Adult; Aggressive Periodontitis; Alveolar Bone Loss; Amoxicillin; Anti-Bacterial Agents; Combined Mo | 2015 |
Interdisciplinary management of aggressive periodontitis.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Combined Modality Therapy; Conn | 2015 |
Bacterial colonization of oral implants from nondental sources.
Topics: Aggressive Periodontitis; Anti-Infective Agents; Bacteria; Bacteroides; Campylobacter rectus; Ciprof | 2009 |
Persistence of extracrevicular bacterial reservoirs after treatment of aggressive periodontitis.
Topics: Adolescent; Adult; Aged; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicilli | 2008 |
Minimally invasive flap surgery and enamel matrix derivative in the treatment of localized aggressive periodontitis: case report.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Bone Loss; Amoxicil | 2009 |
Aggressive periodontitis: a case report.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Bone Loss; Amoxicillin; An | 2008 |
Modified periodontal risk assessment score: long-term predictive value of treatment outcomes. A retrospective study.
Topics: Aggressive Periodontitis; Anti-Infective Agents, Local; Chronic Periodontitis; Dental Scaling; Disea | 2010 |
[Combined therapy in a patient with generalized aggressive periodontitis and rheumatoid arthritis: a 15-year follow up case].
Topics: Adult; Aggressive Periodontitis; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Rheumatoid; | 2010 |
Maintenance after a complex orthoperio treatment in a case of generalized aggressive periodontitis: 7-year result.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Amoxicillin-Pot | 2010 |
[Initial therapy and prosthodontic treatment of a case with aggressive periodontitis combined with periodontal abscesses].
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Combined | 2010 |
Clinical and microbiologic evaluation, by real-time polymerase chain reaction, of non-surgical treatment of aggressive periodontitis associated with amoxicillin and metronidazole.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial | 2012 |
Benefits of early systemic antibiotics in localized aggressive periodontitis: a retrospective study.
Topics: Adolescent; Aggressive Periodontitis; Amoxicillin; Anti-Infective Agents; Black or African American; | 2012 |
Therapeutic management of a case of generalised aggressive periodontitis in an 8-year old child: 18-month results.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar Bone Loss; Amoxicillin; An | 2012 |
Localized prepubertal periodontitis--nonsurgical treatment of an adolescent patient: a case report.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Amoxicillin-Potassium | 1995 |
A 14-year follow-up study of localized juvenile periodontitis treated by scaling and root planing, systemic metronidazole, and subgingival curettage: a case report.
Topics: Adolescent; Aggressive Periodontitis; Antitrichomonal Agents; Dental Scaling; Follow-Up Studies; Hum | 1996 |
Loss of deciduous teeth and germs of permanent incisors in a 4-year-old child. An atypic prepubertal periodontitis? A clinical, microbiological, immunological and ultrastructural study.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Anti-Bacterial Agents; Basement Mem | 1997 |
Subgingival microflora and treatment in prepubertal periodontitis associated with chronic idiopathic neutropenia.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin-Potassium Clavulanate C | 1998 |
Early-onset periodontitis in a patient with Ehlers-Danlos syndrome type III.
Topics: Adolescent; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacte | 1999 |
Periodontal treatment of rapid progressive periodontitis in 2 siblings with Papillon-Lefèvre syndrome: 15-year follow-up.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Anti-Bacterial Agents; Anti-Infecti | 2000 |
A multidisciplinary approach to the diagnosis and treatment of early-onset periodontitis: a case report.
Topics: Adolescent; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacte | 2001 |
Combined mechanical and antibiotic periodontal therapy in a case of Papillon-Lefèvre syndrome.
Topics: Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; | 2001 |
Generalized aggressive periodontitis in a prepubertal patient: a case report.
Topics: Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Alveolar | 2001 |
A preliminary study on the use of a combination of tetracycline and metronidazole in the treatment of refractory periodontitis.
Topics: Aggressive Periodontitis; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Age | 1992 |
Peptostreptococcus micros in human periodontitis.
Topics: Adult; Aged; Aged, 80 and over; Aggressive Periodontitis; Anti-Bacterial Agents; Chi-Square Distribu | 1992 |
Metronidazole plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis.
Topics: Actinobacillus; Adolescent; Adult; Aggressive Periodontitis; Amoxicillin; Bacteroides; Drug Combinat | 1989 |