metronidazole has been researched along with Adhesions, Tissue in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "59 patients with acute pelvic inflammatory diseases proved and classified by laparoscopy were treated by two kinds of therapies in alternating order." | 6.66 | [Adjuvant prednisolone therapy for the prevention of adhesions after acute adnexitis]. ( Akkermann, N; Kolmorgen, K, 1988) |
| "Specimens of abdominal adhesions and bowels of rats were examined at light microscopy in treatment of diffuse purulent peritonitis (DPP) by kanamycin and artificial carbomineral sorbent SUMS-2p with metronidazolum or lipoorizinum adsorbed on the surface." | 3.70 | [Structural formation of adhesions in abdominal cavity and bowel walls in treatment of peritonitis by sorbent with absorbed metrinidazole or lipoorizinum (experimental study)]. ( Maĭborodin, IV; Pleshakov, VP; Velichko, IaI, 1999) |
| "59 patients with acute pelvic inflammatory diseases proved and classified by laparoscopy were treated by two kinds of therapies in alternating order." | 2.66 | [Adjuvant prednisolone therapy for the prevention of adhesions after acute adnexitis]. ( Akkermann, N; Kolmorgen, K, 1988) |
| "Metronidazole was administrated for 5 weeks and symptoms were completely resolved." | 1.39 | Bacteroides fragilis vertebral osteomyelitis complicated by percutaneous epidural adhesiolysis. ( Choi, BK; Han, IH; Kim, SY; Nam, KH, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbas, M | 1 |
| Nafeh, AE | 1 |
| Elsebae, M | 1 |
| Farouk, Y | 1 |
| Bourret, A | 1 |
| Fauconnier, A | 1 |
| Brun, JL | 1 |
| Han, IH | 1 |
| Choi, BK | 1 |
| Nam, KH | 1 |
| Kim, SY | 1 |
| Wang, XC | 1 |
| Gui, CQ | 1 |
| Zheng, QS | 1 |
| Maĭborodin, IV | 1 |
| Velichko, IaI | 1 |
| Pleshakov, VP | 1 |
| Oncel, M | 1 |
| Kurt, N | 1 |
| Remzi, FH | 1 |
| Sensu, SS | 1 |
| Vural, S | 1 |
| Gezen, CF | 1 |
| Cincin, TG | 1 |
| Olcay, E | 1 |
| Kolmorgen, K | 1 |
| Akkermann, N | 1 |
1 review available for metronidazole and Adhesions, Tissue
| Article | Year |
|---|---|
[Management of uncomplicated pelvic inflammatory disease].
Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Chlamydia trachomatis; Drug Resistance, Microbial; | 2012 |
1 trial available for metronidazole and Adhesions, Tissue
| Article | Year |
|---|---|
[Adjuvant prednisolone therapy for the prevention of adhesions after acute adnexitis].
Topics: Ampicillin; Blood Sedimentation; Drug Therapy, Combination; Female; Humans; Metronidazole; Pelvic In | 1988 |
5 other studies available for metronidazole and Adhesions, Tissue
| Article | Year |
|---|---|
Dose related effect of systemic antibiotics in prevention of postoperative intra-abdominal adhesion formation in experimental animals.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Inject | 2008 |
Bacteroides fragilis vertebral osteomyelitis complicated by percutaneous epidural adhesiolysis.
Topics: Adult; Anti-Bacterial Agents; Bacteroides fragilis; Bacteroides Infections; Ceftazidime; Combined Mo | 2013 |
Combined therapy of allantoin, metronidazole, dexamethasone on the prevention of intra-abdominal adhesion in dogs and its quantitative analysis.
Topics: Abdomen; Allantoin; Animals; Dexamethasone; Dogs; Female; Glucocorticoids; Male; Metronidazole; Tiss | 2003 |
[Structural formation of adhesions in abdominal cavity and bowel walls in treatment of peritonitis by sorbent with absorbed metrinidazole or lipoorizinum (experimental study)].
Topics: Abdomen; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Colon; Disease Models, Animal; Drug | 1999 |
The effectiveness of systemic antibiotics in preventing postoperative, intraabdominal adhesions in an animal model.
Topics: Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Fibrosis; Injections, Intramuscular; Metro | 2001 |