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metronidazole and Adenomatous Polyps

metronidazole has been researched along with Adenomatous Polyps in 1 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Adenomatous Polyps: Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The most frequent cause of pseudomembranous colitis is Clostridium difficile (C."1.39Atypical presentation of pseudomembranous colitis localized in adenomatous polyps. ( Alvarez-Lobos, M; Barra-Carrasco, J; Guzmán, AM; Hernández-Rocha, C; Lezcano, G; Paredes-Sabja, D; Zoroquiaín, P, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hernández-Rocha, C1
Barra-Carrasco, J1
Guzmán, AM1
Paredes-Sabja, D1
Lezcano, G1
Zoroquiaín, P1
Alvarez-Lobos, M1

Other Studies

1 other study available for metronidazole and Adenomatous Polyps

ArticleYear
Atypical presentation of pseudomembranous colitis localized in adenomatous polyps.
    World journal of gastroenterology, 2013, Jan-14, Volume: 19, Issue:2

    Topics: Adenomatous Polyps; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Colonic Neop

2013