metronidazole has been researched along with Adenocarcinoma Of Kidney in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matta, SK | 1 |
| Greenberg, A | 1 |
| Singh, A | 1 |
| Stewart, DJ | 1 |
| Futter, N | 1 |
| Irvine, A | 1 |
| Danjoux, C | 1 |
| Moors, D | 1 |
2 other studies available for metronidazole and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
Diarrhea With Clostridium difficile-Positive Stool-Trick or Treat: A Teachable Moment.
Topics: Aged; Anti-Bacterial Agents; Axitinib; Carcinoma, Renal Cell; Clostridioides difficile; Costs and Co | 2015 |
Mitomycin-C and metronidazole in the treatment of advanced renal-cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Female; Humans; | 1987 |