metronidazole has been researched along with Adenitis in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The potential role of anaerobic bacteria in acute tonsillitis was investigated in a retrospective study that evaluated the efficacy of antimicrobial therapy with metronidazole on the management of acute episodes of non-beta-hemolytic streptococcal tonsillitis (NST)." | 7.73 | Treatment of non-streptococcal tonsillitis with metronidazole. ( Brook, I; Gober, AE, 2005) |
| "The potential role of anaerobic bacteria in acute tonsillitis was investigated in a retrospective study that evaluated the efficacy of antimicrobial therapy with metronidazole on the management of acute episodes of non-beta-hemolytic streptococcal tonsillitis (NST)." | 3.73 | Treatment of non-streptococcal tonsillitis with metronidazole. ( Brook, I; Gober, AE, 2005) |
| "Unilateral suppurative cervical lymphadenitis is characterized by acute onset of 1 or more tender cervical lymph nodes and can lead to fever, cellulitis, abscess formation, and bacteremia." | 1.37 | Management of suppurative cervical lymphadenitis in a healthy 24-year-old man. ( Cabrera, J; Chowdhury, R; Hardigan, PC; Hernandez, M; Woods, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernandez, M | 1 |
| Chowdhury, R | 1 |
| Woods, J | 1 |
| Cabrera, J | 1 |
| Hardigan, PC | 1 |
| Yang, H | 1 |
| Guo, XC | 1 |
| Yan, XD | 1 |
| Brook, I | 1 |
| Gober, AE | 1 |
| Simo, R | 1 |
| Hartley, C | 1 |
| Rapado, F | 1 |
| Zarod, AP | 1 |
| Sanyal, D | 1 |
| Rothera, MP | 1 |
| Mayhew, KM | 1 |
| Dundoo, M | 1 |
| Dunne, EF | 1 |
| Dwinnell, BG | 1 |
| Stephens, JK | 1 |
| Luger, A | 1 |
1 review available for metronidazole and Adenitis
| Article | Year |
|---|---|
Inguinal lymphadenitis caused by Entamoeba histolytica: case report and literature review.
Topics: Adult; Animals; Anti-Infective Agents; Entamoeba histolytica; Entamoebiasis; Groin; Humans; Immunohi | 2000 |
1 trial available for metronidazole and Adenitis
| Article | Year |
|---|---|
[Physiotherapy with drugs for acute lymphadenitis of face and neck].
Topics: Acute Disease; Child; Child, Preschool; Combined Modality Therapy; Face; Female; Humans; Lymphadenit | 2003 |
4 other studies available for metronidazole and Adenitis
| Article | Year |
|---|---|
Management of suppurative cervical lymphadenitis in a healthy 24-year-old man.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceph | 2011 |
Treatment of non-streptococcal tonsillitis with metronidazole.
Topics: Adolescent; Anti-Infective Agents; Bacteria, Anaerobic; Child; Female; Fever; Humans; Lymphadenitis; | 2005 |
Microbiology and antibiotic treatment of head and neck abscesses in children.
Topics: Abscess; Adolescent; Anti-Bacterial Agents; Bacteria, Anaerobic; Child; Child, Preschool; Drainage; | 1998 |
[Syphilis diagnosis in the age of antibiotics].
Topics: Adult; Aged; Alopecia; Anti-Bacterial Agents; Balanitis; Biopsy; Child; Child, Preschool; Chloramphe | 1971 |