metronidazole has been researched along with Acute Bacterial Prostatitis in 17 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The concentration of metronidazole has been studied in blood and in seminal plasma from apparently healthy volunteers and men with subclinical prostatitis." | 3.66 | Secretion of metronidazole into the human semen. ( Dornbusch, K; Eliasson, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (82.35) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vickovic, N | 1 |
| Skerk, V | 3 |
| Granic, J | 2 |
| Vargovic, M | 1 |
| Pasini, M | 1 |
| Turcic, P | 1 |
| Markotic, A | 1 |
| Andrasevic, S | 1 |
| Begovac, J | 1 |
| Schönwald, S | 1 |
| Krhen, I | 1 |
| Barsić, B | 1 |
| Mareković, I | 1 |
| Roglić, S | 1 |
| Desnica, B | 1 |
| Zeljko, Z | 1 |
| DRAPER, JW | 1 |
| AKBARI, A | 1 |
| WARD, JN | 1 |
| Amar, AD | 1 |
| Goff, DA | 1 |
| Davidson, RA | 1 |
| Lockie, AC | 1 |
| Maskell, R | 1 |
| Eliasson, R | 1 |
| Dornbusch, K | 1 |
| Zabkowski, T | 1 |
| Peterek, J | 1 |
| Stawarz, B | 1 |
| Bejm, J | 1 |
| Sulik, M | 1 |
| Bańcer, M | 1 |
| Saultz, JW | 1 |
| Toffler, WL | 1 |
| van Laarhoven, PH | 1 |
| Catterall, RD | 2 |
| Haschek, H | 1 |
| Kofler, K | 1 |
| Marberger, H | 1 |
| Decristoforo, A | 1 |
| Swoboda, HP | 1 |
| Kawamura, N | 1 |
| Völter, D | 1 |
1 review available for metronidazole and Acute Bacterial Prostatitis
| Article | Year |
|---|---|
[Trichomonas vaginalis infection in the male].
Topics: Chronic Disease; Coitus; Epididymitis; Humans; Infertility, Male; Male; Metronidazole; Prostatitis; | 1973 |
2 trials available for metronidazole and Acute Bacterial Prostatitis
| Article | Year |
|---|---|
Metronidazole 1.5 gram dose for 7 or 14 days in the treatment of patients with chronic prostatitis caused by Trichomonas vaginalis: A randomized study.
Topics: Adult; Drug Administration Schedule; Humans; Male; Metronidazole; Prostatitis; Time Factors; Trichom | 2010 |
Chronic prostatitis caused by Trichomonas vaginalis--diagnosis and treatment.
Topics: Animals; Anti-Infective Agents; Chronic Disease; Drug Administration Schedule; Humans; Inflammation; | 2002 |
14 other studies available for metronidazole and Acute Bacterial Prostatitis
| Article | Year |
|---|---|
THERAPEUTIC PROBLEMS IN URINARY INFECTIONS.
Topics: Chloramphenicol; Enterobacter aerogenes; Escherichia coli Infections; Humans; Hydrocortisone; Imidaz | 1964 |
Probable Trichomonas vaginalis epididymitis.
Topics: Adult; Cystoscopy; Diagnosis, Differential; Epididymitis; Humans; Male; Metronidazole; Prostatitis; | 1967 |
Amebic prostatitis.
Topics: Adult; Amebiasis; Entamoeba histolytica; Entamoebiasis; Humans; Male; Metronidazole; Prostatitis | 1984 |
Symptomatic cure of prostatitis with metronidazole.
Topics: Adult; Chronic Disease; Humans; Male; Metronidazole; Prostatitis | 1981 |
Gardnerella vaginalis and prostatitis.
Topics: Corynebacterium; Corynebacterium Infections; Humans; Male; Metronidazole; Prostatitis | 1981 |
Secretion of metronidazole into the human semen.
Topics: Adult; Humans; Male; Metronidazole; Prostate; Prostatitis; Semen; Seminal Vesicles; Vas Deferens | 1980 |
[The results of treatment of chronic prostatitis on the background of anaerobic bacterial and fungal infections].
Topics: Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Bacterial Infections; Chronic Disease; | 1999 |
Trichomonas infections in men.
Topics: Adult; Humans; Male; Metronidazole; Prostatitis; Trichomonas Infections; Urethritis | 1989 |
Trichomonas vaginalis, a pathogen of prostatitis.
Topics: Adult; Aged; Humans; Male; Metronidazole; Middle Aged; Prostatitis; Staining and Labeling; Trichomon | 1967 |
Trichomonal infections of the genital tract.
Topics: Coitus; Female; Genital Diseases, Male; Humans; Male; Metronidazole; Pregnancy; Prostatitis; Trichom | 1972 |
[Fertility disorders due to inflammatory male adnexal diseases].
Topics: Abscess; Adult; Fructose; Genital Diseases, Male; Humans; Infertility, Male; Male; Metronidazole; Mi | 1972 |
[Studies on Trichomonas vaginalis in urological field. VI. Clinical efficacy of various drugs].
Topics: Adult; Antifungal Agents; Female; Humans; Male; Metronidazole; Nitrofurans; Nitrofurantoin; Prostati | 1973 |
[Treatment of prostatitis].
Topics: Abscess; Acute Disease; Anti-Bacterial Agents; Chronic Disease; Focal Infection; Gonorrhea; Humans; | 1971 |
Treatment of trichomonal prostatitis with metronidazole.
Topics: Humans; Male; Metronidazole; Prostatitis; Trichomonas Infections | 1965 |