metronidazole has been researched along with Acariasis in 40 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of topical ivermectin-metronidazole combined therapy in the management of Demodex-associatedblepharitis." | 9.41 | Topical ivermectin-metronidazole gel therapy in the treatment of blepharitis caused by Demodex spp.: A randomized clinical trial. ( Ávila, MY; Martínez-Pulgarín, DF; Rizo Madrid, C, 2021) |
| "Two-hundred patients with mites folliculitis were sequentially treated with either an ornidazole- or metronidazole-based regimen." | 9.22 | Treatment of mites folliculitis with an ornidazole-based sequential therapy: A randomized trial. ( Luan, XL; Luo, Y; Sun, YJ; Zhang, L, 2016) |
| "Permethrin 5% cream is a safe alternative for the topical treatment of papulopustular rosacea." | 7.72 | Is permethrin 5% cream effective for rosacea? ( Swenor, ME, 2003) |
| "To evaluate the efficacy of topical ivermectin-metronidazole combined therapy in the management of Demodex-associatedblepharitis." | 5.41 | Topical ivermectin-metronidazole gel therapy in the treatment of blepharitis caused by Demodex spp.: A randomized clinical trial. ( Ávila, MY; Martínez-Pulgarín, DF; Rizo Madrid, C, 2021) |
| "Two-hundred patients with mites folliculitis were sequentially treated with either an ornidazole- or metronidazole-based regimen." | 5.22 | Treatment of mites folliculitis with an ornidazole-based sequential therapy: A randomized trial. ( Luan, XL; Luo, Y; Sun, YJ; Zhang, L, 2016) |
| "A range of treatment options are available in rosacea, which include several topical (mainly metronidazole, azelaic acid, other antibiotics, sulfur, retinoids) and oral drugs (mainly tetracyclines, metronidazole, macrolides)." | 3.77 | [Treatment of rosacea]. ( Cozzani, E; Drago, F; Gallo, R; Paolino, S; Parodi, A, 2011) |
| "A range of treatment options are available in rosacea, which include several topical (mainly metronidazole, azelaic acid, other antibiotics, sulfur, retinoids) and oral drugs (mainly tetracyclines, metronidazole, macrolides)." | 3.77 | Treatment of rosacea. ( Cozzani, E; Drago, F; Gallo, R; Paolino, S; Parodi, A, 2011) |
| "Permethrin 5% cream is a safe alternative for the topical treatment of papulopustular rosacea." | 3.72 | Is permethrin 5% cream effective for rosacea? ( Swenor, ME, 2003) |
| "Granulomatous rosacea is a rare chronic inflammatory skin disease with an unknown origin." | 1.46 | Granulomatous rosacea: a case report. ( Kelati, A; Mernissi, FZ, 2017) |
| " Mites were found in sputum in 121 persons who were then treated with metronidazole, twice a day with a daily dosage of 0." | 1.33 | [Survey and treatment of pulmonary acariasis among the workers involving in traditional Chinese medicinal materials]. ( Chen, XB; Hu, SF; Ru, XY; Shao, XY; Xia, H, 2005) |
| "A survey on pulmonary acariasis was carried out in the grain store and in the Chinese medicinal herb plant." | 1.28 | [Clinical manifestation and treatment of pulmonary acariasis]. ( Chen, XB; Hu, SF; Sun, X, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.00) | 18.7374 |
| 1990's | 5 (12.50) | 18.2507 |
| 2000's | 10 (25.00) | 29.6817 |
| 2010's | 18 (45.00) | 24.3611 |
| 2020's | 5 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Wei, E | 1 |
| Reisinger, A | 1 |
| French, LE | 1 |
| Clanner-Engelshofen, BM | 1 |
| Reinholz, M | 1 |
| Ansorge, C | 1 |
| Technau-Hafsi, K | 1 |
| Jacob, S | 1 |
| VanDaele, MA | 1 |
| Brown, JN | 1 |
| Krispinsky, A | 1 |
| Zirwas, M | 1 |
| Ávila, MY | 1 |
| Martínez-Pulgarín, DF | 1 |
| Rizo Madrid, C | 1 |
| Neema, S | 1 |
| Subramaniyan, R | 1 |
| Kinra, P | 1 |
| Hedberg, ML | 1 |
| Chibnall, RJ | 1 |
| Compton, LA | 1 |
| van Atteveld, JE | 1 |
| Graaf, M | 1 |
| Grotel, MV | 1 |
| van den Heuvel-Eibrink, MM | 1 |
| Kelati, A | 1 |
| Mernissi, FZ | 1 |
| Álvarez-Salafranca, M | 1 |
| Vicente, A | 1 |
| Prat Torres, C | 1 |
| Combalia, A | 1 |
| Monsonís, M | 1 |
| Celis-Passini, VP | 1 |
| González-Enseñat, MA | 1 |
| Ünal, E | 1 |
| Güvendi Akçınar, U | 1 |
| Arduç, A | 1 |
| Navel, V | 1 |
| Mulliez, A | 1 |
| Benoist d'Azy, C | 1 |
| Baker, JS | 1 |
| Malecaze, J | 1 |
| Chiambaretta, F | 1 |
| Dutheil, F | 1 |
| Franco-Álvarez de Luna, F | 1 |
| Santos Rosa, C | 1 |
| Fernández-Villalón, JÁ | 1 |
| Kim, BR | 1 |
| Park, HS | 1 |
| Yoon, HS | 1 |
| Cho, S | 1 |
| Arrúa, M | 1 |
| Samudio, M | 1 |
| Fariña, N | 1 |
| Cibils, D | 1 |
| Laspina, F | 1 |
| Sanabria, R | 1 |
| Carpinelli, L | 1 |
| Mino de Kaspar, H | 1 |
| Sattler, EC | 1 |
| Hoffmann, VS | 1 |
| Ruzicka, T | 1 |
| Braunmühl, TV | 1 |
| Berking, C | 1 |
| Luo, Y | 1 |
| Sun, YJ | 1 |
| Zhang, L | 1 |
| Luan, XL | 1 |
| Larios, G | 1 |
| Alevizos, A | 1 |
| Perimeni, D | 1 |
| Rigopoulos, D | 1 |
| Katsambas, A | 1 |
| Cheikhrouhou, F | 1 |
| Makni, F | 1 |
| Neji, S | 1 |
| Sellami, H | 1 |
| Masmoudi, A | 1 |
| Turki, H | 1 |
| Ben Zina, Z | 1 |
| Fki, J | 1 |
| Ayadi, A | 1 |
| Parodi, A | 2 |
| Drago, F | 2 |
| Paolino, S | 2 |
| Cozzani, E | 2 |
| Gallo, R | 2 |
| Vu, JR | 1 |
| English, JC | 1 |
| Nath, AK | 1 |
| Timshina, DK | 1 |
| Thappa, DM | 1 |
| Sinclair, R | 1 |
| Salem, DA | 1 |
| El-Shazly, A | 1 |
| Nabih, N | 1 |
| El-Bayoumy, Y | 1 |
| Saleh, S | 1 |
| Swenor, ME | 1 |
| Schaller, M | 1 |
| Sander, CA | 1 |
| Plewig, G | 1 |
| El-Shazly, AM | 1 |
| Hassan, AA | 1 |
| Soliman, M | 1 |
| Morsy, GH | 1 |
| Morsy, TA | 1 |
| Ballestero-Díez, M | 1 |
| Daudén, E | 1 |
| Ruíz-Genao, DP | 1 |
| Fraga, J | 1 |
| García-Díez, A | 1 |
| Fichtel, JC | 1 |
| Wiggins, AK | 1 |
| Lesher, JL | 1 |
| Xia, H | 1 |
| Hu, SF | 2 |
| Chen, XB | 2 |
| Ru, XY | 1 |
| Shao, XY | 1 |
| Aydogan, K | 1 |
| Alver, O | 1 |
| Tore, O | 1 |
| Karadogan, SK | 1 |
| Boutli, F | 1 |
| Delli, FS | 1 |
| Mourellou, O | 1 |
| Glukhen'kiĭ, BT | 1 |
| Snitsanenko, OV | 1 |
| Hoekzema, R | 1 |
| Hulsebosch, HJ | 1 |
| Bos, JD | 1 |
| Barrio, J | 1 |
| Lecona, M | 1 |
| Hernanz, JM | 1 |
| Sánchez, M | 1 |
| Gurbindo, MD | 1 |
| Lázaro, P | 1 |
| Barrio, JL | 1 |
| Patrizi, A | 1 |
| Neri, I | 1 |
| Chieregato, C | 1 |
| Misciali, M | 1 |
| Junk, AK | 1 |
| Lukacs, A | 1 |
| Kampik, A | 1 |
| Baima, B | 1 |
| Sticherling, M | 1 |
| Sun, X | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
| Burmeister, V | 1 |
6 reviews available for metronidazole and Acariasis
| Article | Year |
|---|---|
Comparison of Different Anti-Demodex Strategies: A Systematic Review and Meta-Analysis.
Topics: Animals; Humans; Ivermectin; Metronidazole; Mite Infestations; Mites; Permethrin; Skin | 2023 |
Treatment of Demodex-associated inflammatory skin conditions: A systematic review.
Topics: Administration, Topical; Benzoates; Folliculitis; Humans; Metronidazole; Mite Infestations; Permethr | 2019 |
Symptomatic vulvar demodicosis: A case report and review of the literature.
Topics: Administration, Oral; Administration, Topical; Adult; Animals; Antiparasitic Agents; Antiprotozoal A | 2020 |
Efficacy of treatments for Demodex blepharitis: A systematic review and meta-analysis.
Topics: Animals; Anti-Infective Agents, Local; Antiparasitic Agents; Blepharitis; Eye Infections, Parasitic; | 2019 |
Rosacea-like demodicosis in an HIV-positive child.
Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antitrichomonal Agents; Child, Prescho | 1996 |
Demodicidosis revisited.
Topics: Adult; Age Distribution; Animals; Biopsy, Needle; Child; Child, Preschool; Diagnosis, Differential; | 2002 |
5 trials available for metronidazole and Acariasis
| Article | Year |
|---|---|
Topical ivermectin-metronidazole gel therapy in the treatment of blepharitis caused by Demodex spp.: A randomized clinical trial.
Topics: Blepharitis; Eyelashes; Humans; Ivermectin; Metronidazole; Mite Infestations | 2021 |
Comparative study of the efficacy of different treatment options in patients with chronic blepharitis.
Topics: Administration, Ophthalmic; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agen | 2015 |
Treatment of mites folliculitis with an ornidazole-based sequential therapy: A randomized trial.
Topics: Adult; Drug Therapy, Combination; Female; Folliculitis; Humans; Male; Metronidazole; Middle Aged; Mi | 2016 |
Evaluation of the efficacy of oral ivermectin in comparison with ivermectin-metronidazole combined therapy in the treatment of ocular and skin lesions of Demodex folliculorum.
Topics: Acari; Administration, Oral; Adult; Animals; Drug Therapy, Combination; Eye Infections, Parasitic; F | 2013 |
Treatment of human Demodex folliculorum by camphor oil and metronidazole.
Topics: Adolescent; Adult; Animals; Antitrichomonal Agents; Child; Cinnamomum camphora; Facial Dermatoses; F | 2004 |
29 other studies available for metronidazole and Acariasis
| Article | Year |
|---|---|
[Granulomatous rosacea in a lung transplant recipient : A possible therapy option in a unique group of patients].
Topics: Aged; Animals; Humans; Immunocompromised Host; Insecticides; Ivermectin; Metronidazole; Mite Infesta | 2020 |
Nodular Demodicosis in a Pregnant Woman Treated with Oral Ivermectin and Metronidazole.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Antiparasitic Agents; Drug Therapy, Combination; | 2019 |
Demodex induced facial frictional melanoses.
Topics: Anti-Infective Agents; Antiparasitic Agents; Drug Therapy, Combination; Facial Dermatoses; Female; F | 2020 |
Demodicosis in Pediatric Cancer.
Topics: Child; Humans; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Male; Metronidazole; Mite Infestations; Trea | 2017 |
Granulomatous rosacea: a case report.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Humans; Male; Metronidazole; Middle Aged; M | 2017 |
Demodicosis in two patients with a previous history of Langerhans cell histiocytosis.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Child, Preschool; Female; Histiocytosis, Lang | 2017 |
Hidradenitis Suppurativa, Metabolic Syndrome, and Demodex spp. Infestation.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Bacterial Agents; Antiparasitic Agent | 2018 |
[Resistance to routine ophthalmological treatments in a patient with chronic blepharitis].
Topics: Acaricides; Adolescent; Animals; Blepharitis; Boric Acids; Chronic Disease; Drug Resistance; Eyelash | 2014 |
Demodicidosis on the arms of a patient with pemphigus foliaceus.
Topics: Animals; Antiprotozoal Agents; Arm; Comorbidity; Hexachlorocyclohexane; Humans; Male; Metronidazole; | 2014 |
Reflectance confocal microscopy for monitoring the density of Demodex mites in patients with rosacea before and after treatment.
Topics: Adult; Aged; Animals; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Facial Dermatos | 2015 |
Rosacea-like demodicidosis.
Topics: Diagnostic Errors; Female; Humans; Metronidazole; Middle Aged; Mite Infestations; Rosacea | 2008 |
[Human demodicidosis in Sfax area (Tunisia)].
Topics: Adolescent; Adult; Aged; Animals; Antiprotozoal Agents; Blepharitis; Child; Ear; Female; Forehead; H | 2010 |
[Treatment of rosacea].
Topics: Adapalene; Anti-Infective Agents; Cyclosporine; Dermatologic Agents; Dicarboxylic Acids; Humans; Imm | 2011 |
Demodex folliculitis.
Topics: Acari; Adult; Animals; Anti-Infective Agents, Local; Female; Folliculitis; Humans; Metronidazole; Mi | 2011 |
Treatment of rosacea.
Topics: Anti-Infective Agents; Cyclosporine; Dermatologic Agents; Dicarboxylic Acids; Humans; Immunosuppress | 2011 |
Demodex in an aerobic environment on the eyelashes.
Topics: Acari; Adult; Animals; Anti-Infective Agents; Antiparasitic Agents; Blepharitis; Eyelashes; Humans; | 2012 |
Is permethrin 5% cream effective for rosacea?
Topics: Animals; Antitrichomonal Agents; Evidence-Based Medicine; Humans; Insecticides; Metronidazole; Mite | 2003 |
Demodex abscesses: clinical and therapeutic challenges.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Diagnosis, Differential; Erythema; Facial Derm | 2003 |
Presence of Demodex in follicular hyperkeratotic spicules on the face. A casual association?
Topics: Aged; Animals; Anti-Infective Agents; Facial Dermatoses; Female; Hair Follicle; Humans; Keratosis; M | 2004 |
Plaque-forming demodicidosis.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Antiparasitic Agents; Facial Dermatoses; Female; | 2005 |
[Survey and treatment of pulmonary acariasis among the workers involving in traditional Chinese medicinal materials].
Topics: Adolescent; Adult; Anti-Infective Agents; Drugs, Chinese Herbal; Female; Humans; Lung Diseases, Para | 2005 |
Facial abscess-like conglomerates associated with Demodex mites.
Topics: Abscess; Adult; Facial Dermatoses; Humans; Male; Metronidazole; Mite Infestations | 2006 |
Demodicidosis as spinulosis of the face: a therapeutic challenge.
Topics: Aged; Anti-Infective Agents; Combined Modality Therapy; Facial Dermatoses; Humans; Hydroxyurea; Low- | 2007 |
[Rosacea and demodicosis (a review of the literature)].
Topics: Animals; Cryosurgery; Dermabrasion; Electrocoagulation; Humans; Metronidazole; Mite Infestations; Mi | 1984 |
Demodicidosis or rosacea: what did we treat?
Topics: Aged; Animals; Diagnosis, Differential; Facial Dermatoses; Humans; Male; Metronidazole; Mite Infesta | 1995 |
Demodicidosis in immunocompetent young children: report of eight cases.
Topics: Child, Preschool; Female; Humans; Immunocompetence; Infant; Male; Metronidazole; Mite Infestations | 1997 |
[Topical administration of metronidazole gel as an effective therapy alternative in chronic Demodex blepharitis--a case report].
Topics: Administration, Topical; Adult; Animals; Anti-Infective Agents; Blepharitis; Female; Follow-Up Studi | 1998 |
[Clinical manifestation and treatment of pulmonary acariasis].
Topics: Adolescent; Adult; Aged; Female; Humans; Lung Diseases; Male; Metronidazole; Middle Aged; Mite Infes | 1990 |
Unilateral demodectic rosacea.
Topics: Adult; Dermatitis; Humans; Male; Metronidazole; Mite Infestations; Rosacea; Toluidines | 1989 |