metronidazole has been researched along with Acalculous Cholecystitis in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Acalculous Cholecystitis: Inflammation of the GALLBLADDER wall in the absence of GALLSTONES.
Excerpt | Relevance | Reference |
---|---|---|
"Malaria has been associated with acute acalculous cholecystitis, a very uncommon complication in children." | 2.58 | Acalculous Cholecystitis in a Pediatric Patient With Plasmodium Falciparum Infection: A Case Report and Literature Review. ( Aguilera-Alonso, D; Del Rosal, T; Escosa-García, L; García-Hortelano, M; López Medina, EM; Villota Arrieta, J, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Aguilera-Alonso, D | 1 |
López Medina, EM | 1 |
Del Rosal, T | 1 |
Villota Arrieta, J | 1 |
Escosa-García, L | 1 |
García-Hortelano, M | 1 |
1 review available for metronidazole and Acalculous Cholecystitis
Article | Year |
---|---|
Acalculous Cholecystitis in a Pediatric Patient With Plasmodium Falciparum Infection: A Case Report and Literature Review.
Topics: Acalculous Cholecystitis; Acute Kidney Injury; Administration, Intravenous; Anti-Bacterial Agents; A | 2018 |