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metronidazole and Acalculous Cholecystitis

metronidazole has been researched along with Acalculous Cholecystitis in 1 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Acalculous Cholecystitis: Inflammation of the GALLBLADDER wall in the absence of GALLSTONES.

Research Excerpts

ExcerptRelevanceReference
"Malaria has been associated with acute acalculous cholecystitis, a very uncommon complication in children."2.58Acalculous Cholecystitis in a Pediatric Patient With Plasmodium Falciparum Infection: A Case Report and Literature Review. ( Aguilera-Alonso, D; Del Rosal, T; Escosa-García, L; García-Hortelano, M; López Medina, EM; Villota Arrieta, J, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aguilera-Alonso, D1
López Medina, EM1
Del Rosal, T1
Villota Arrieta, J1
Escosa-García, L1
García-Hortelano, M1

Reviews

1 review available for metronidazole and Acalculous Cholecystitis

ArticleYear
Acalculous Cholecystitis in a Pediatric Patient With Plasmodium Falciparum Infection: A Case Report and Literature Review.
    The Pediatric infectious disease journal, 2018, Volume: 37, Issue:2

    Topics: Acalculous Cholecystitis; Acute Kidney Injury; Administration, Intravenous; Anti-Bacterial Agents; A

2018