metronidazole has been researched along with Abscess, Retropharyngeal in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collis, DH | 1 |
| Sanu, A | 1 |
| Zeitoun, IM | 1 |
| Dhanarajani, PJ | 1 |
| Karkanevatos, A | 1 |
| Beasley, NJ | 1 |
| Swift, AC | 1 |
| Harries, PG | 1 |
| Feldman, DP | 1 |
| Picerno, NA | 1 |
| Porubsky, ES | 1 |
2 reviews available for metronidazole and Abscess, Retropharyngeal
| Article | Year |
|---|---|
Cervical cellulitis and mediastinitis caused by odontogenic infections: report of two cases and review of literature.
Topics: Adult; Amikacin; Fatal Outcome; Focal Infection, Dental; Humans; Ludwig's Angina; Male; Mediastinal | 1995 |
Acute non-tuberculous retropharyngeal abscess in an adult. A case report and review of the literature.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Cefotaxime; Drug Therapy, Combination; Female; Humans | 1997 |
3 other studies available for metronidazole and Abscess, Retropharyngeal
| Article | Year |
|---|---|
Zygomatic haematoma in an 11-month-old helps diagnose retropharyngeal abscess, with concurrent tonsillitis and subsequent infant tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anorexia; Anti-Bacterial Agents; Cefotaxime; Dexamethasone; | 2016 |
Retropharyngeal abscess and acute torticollis.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antitrichomonal Agent | 1997 |
Cavernous sinus thrombosis complicating odontogenic parapharyngeal space neck abscess: a case report and discussion.
Topics: Aged; Anti-Infective Agents; Cavernous Sinus Thrombosis; Ceftriaxone; Cephalosporins; Combined Modal | 2000 |