metronidazole has been researched along with Abscess, Periodontal in 19 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of metronidazole and doxycycline in preventing recurrent periodontitis was studied in 23 patients." | 9.07 | Serial doxycycline and metronidazole in prevention of recurrent periodontitis in high-risk patients. ( Aitken, S; Birek, P; Kulkarni, GV; Lee, WL; McCulloch, CA, 1992) |
| "The efficacy of metronidazole and doxycycline in preventing recurrent periodontitis was studied in 23 patients." | 5.07 | Serial doxycycline and metronidazole in prevention of recurrent periodontitis in high-risk patients. ( Aitken, S; Birek, P; Kulkarni, GV; Lee, WL; McCulloch, CA, 1992) |
| " Despite this there remains little evidence-based literature on what should be prescribed for any given clinical situation, at what dosage and for how long." | 2.45 | The role of phenoxymethylpenicillin, amoxicillin, metronidazole and clindamycin in the management of acute dentoalveolar abscesses--a review. ( Ellison, SJ, 2009) |
| "Forty-one periodontal abscess samples were cultivated on selective and non-selective culture media to isolate the oral anaerobes." | 1.40 | Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses. ( Chen, J; He, J; Miao, X; Wu, X; Xie, Y; Xu, B; Xu, M; Yu, L; Zhang, W, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, Y | 1 |
| Chen, J | 1 |
| He, J | 1 |
| Miao, X | 1 |
| Xu, M | 1 |
| Wu, X | 1 |
| Xu, B | 1 |
| Yu, L | 1 |
| Zhang, W | 1 |
| Gillam, DG | 1 |
| Turner, W | 1 |
| O'Connell, S | 1 |
| Yeaton, K | 1 |
| Kwok, J | 1 |
| Ellison, SJ | 1 |
| Tang, XL | 1 |
| Lin, L | 1 |
| He, JL | 1 |
| Yu, LY | 1 |
| Chen, JZ | 1 |
| Roy, S | 1 |
| Ellenbogen, JM | 1 |
| Wagner, KW | 1 |
| Schön, R | 1 |
| Schumacher, M | 1 |
| Schmelzeisen, R | 1 |
| Schulze, D | 1 |
| Siminoski, K | 1 |
| Eksteen, H | 1 |
| López, NJ | 1 |
| Gamonal, JA | 1 |
| Martinez, B | 1 |
| De Soyza, A | 1 |
| Higgins, B | 1 |
| Gould, K | 1 |
| Feldman, DP | 1 |
| Picerno, NA | 1 |
| Porubsky, ES | 1 |
| Jones, JH | 1 |
| Teng, YT | 1 |
| Sodek, J | 1 |
| McCulloch, CA | 2 |
| Aitken, S | 1 |
| Birek, P | 1 |
| Kulkarni, GV | 1 |
| Lee, WL | 1 |
| Matney, J | 1 |
| Niedzielska-Pietraszek, K | 1 |
| Struzak-Wysokińska, M | 1 |
2 reviews available for metronidazole and Abscess, Periodontal
| Article | Year |
|---|---|
The role of phenoxymethylpenicillin, amoxicillin, metronidazole and clindamycin in the management of acute dentoalveolar abscesses--a review.
Topics: Acute Disease; Adult; Amoxicillin; Anti-Bacterial Agents; Clindamycin; Drainage; Drug Resistance, Ba | 2009 |
Persistent fever due to occult dental infection: case report and review.
Topics: Erythromycin; Female; Fever of Unknown Origin; Humans; Metronidazole; Middle Aged; Periodontal Absce | 1993 |
3 trials available for metronidazole and Abscess, Periodontal
| Article | Year |
|---|---|
Repeated metronidazole and amoxicillin treatment of periodontitis. A follow-up study.
Topics: Adult; Aged; Amoxicillin; Analysis of Variance; Anti-Infective Agents; Chronic Disease; Disease Prog | 2000 |
Serial doxycycline and metronidazole in prevention of recurrent periodontitis in high-risk patients.
Topics: Bacteria; Dental Plaque Index; Dental Scaling; Doxycycline; Drug Therapy, Combination; Female; Human | 1992 |
[Clinical evaluation of metronidazole in the treatment of the periodontal abscesses].
Topics: Humans; Metronidazole; Periodontal Abscess | 1990 |
14 other studies available for metronidazole and Abscess, Periodontal
| Article | Year |
|---|---|
Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Proteins; Bacteriological Techniq | 2014 |
Antibiotics in the treatment of periodontal disease: a guide for the general dental practitioner.
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Biofilms; Chronic Periodontitis | 2014 |
An audit to assess compliance with antimicrobial prescribing in the management of acute dentoalveolar infections with associated facial swelling.
Topics: Amoxicillin; Anti-Bacterial Agents; Dental Audit; Dental Service, Hospital; Drainage; Drug Administr | 2014 |
[Initial therapy and prosthodontic treatment of a case with aggressive periodontitis combined with periodontal abscesses].
Topics: Adult; Aggressive Periodontitis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Combined | 2010 |
[Update on current care guidelines: antimicrobials in acute dentistry].
Topics: Amoxicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clavulanic Acid; Disease Susceptibility; | 2011 |
[Distribution of anaerobes in periodontal abscess and its resistance to antibiotics].
Topics: Adult; Anti-Bacterial Agents; Bacteria, Anaerobic; Cefmetazole; Clindamycin; Drug Resistance, Bacter | 2012 |
Seizures, frontal lobe mass, and remote history of periodontal abscess.
Topics: Actinomyces; Actinomycosis; Anti-Infective Agents; Brain Abscess; Corpus Callosum; Craniotomy; Dose- | 2005 |
Case report: brain and liver abscesses caused by oral infection with Streptococcus intermedius.
Topics: Adult; Anti-Bacterial Agents; Brain Abscess; Drainage; Focal Infection, Dental; Humans; Liver Absces | 2006 |
The effect of adjunctive antibiotic cover during scaling and rootplaning: a case report.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Dental Scaling; Drug Therapy, Combination; Hum | 1997 |
An unusual case of pulmonary abscess.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Brain Abscess; Cefaclor; Cephalosporins; Diagnosis, Diffe | 2000 |
Cavernous sinus thrombosis complicating odontogenic parapharyngeal space neck abscess: a case report and discussion.
Topics: Aged; Anti-Infective Agents; Cavernous Sinus Thrombosis; Ceftriaxone; Cephalosporins; Combined Modal | 2000 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi | 1975 |
Gingival crevicular fluid gelatinase and its relationship to periodontal disease in human subjects.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Chi-Square Distribution; Clinical Enzyme Tests; Colla | 1992 |
Your patient and antibiotics.
Topics: Clindamycin; Humans; Metronidazole; Periodontal Abscess; Tetracyclines | 1991 |