metronidazole has been researched along with Abscess, Intracranial, Subdural in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In particular parietal subdural empyema of odontogenic origin has not been described." | 1.40 | Parietal subdural empyema as complication of acute odontogenic sinusitis: a case report. ( Ferrara, S; Gambino, A; Martines, F; Mucia, M; Salvago, P; Sireci, F, 2014) |
| "Sinusitis was suspected as the cause in only one patient initially." | 1.31 | Suppurative intracranial complications of sinusitis in children. ( Ong, YK; Tan, HK, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diouf, MS | 1 |
| Tall, A | 1 |
| Ndiaye, C | 1 |
| Thiam, A | 1 |
| Deguenonvo, R | 1 |
| Ndiaye, M | 1 |
| Al Salihi, M | 1 |
| Kheiri, B | 1 |
| Abu Sitta, E | 1 |
| Kanzy, A | 1 |
| Martines, F | 1 |
| Salvago, P | 1 |
| Ferrara, S | 1 |
| Mucia, M | 1 |
| Gambino, A | 1 |
| Sireci, F | 1 |
| Romero-Pizarro, Y | 1 |
| Muñoz-Algarra, M | 1 |
| Fernández-Mateos, C | 1 |
| Sánchez-Romero, I | 1 |
| Ong, YK | 1 |
| Tan, HK | 1 |
| Kalaycý, M | 1 |
| Cadavi, F | 1 |
| Altunkaya, H | 1 |
| Gül, S | 1 |
| Ackgöz, B | 1 |
| Weiner, GM | 1 |
| Williams, B | 1 |
| Sandoe, JA | 1 |
| Struthers, JK | 1 |
| Brazier, JS | 1 |
| Leys, D | 1 |
| Christiaens, JL | 1 |
| Derambure, P | 1 |
| Hladky, JP | 1 |
| Lesoin, F | 1 |
| Rousseaux, M | 1 |
| Jomin, M | 1 |
| Petit, H | 1 |
| Savitz, MH | 1 |
| Dickinson, T | 1 |
1 review available for metronidazole and Abscess, Intracranial, Subdural
| Article | Year |
|---|---|
[Postoperative recurrence of subdural empyema].
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Combined Modality Therap | 2011 |
9 other studies available for metronidazole and Abscess, Intracranial, Subdural
| Article | Year |
|---|---|
Complications of sinusitis: An 80-case series from the ENT and neurosurgery departments of the Fann university hospital center of Dakar, Senegal.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Brain Abscess; Child; Child, Preschool; Cla | 2020 |
Sterile subdural empyema: an unusual presentation.
Topics: Aged; Anti-Bacterial Agents; Biopsy; Brain; Ceftriaxone; Diagnosis, Differential; Drainage; Empyema, | 2017 |
Parietal subdural empyema as complication of acute odontogenic sinusitis: a case report.
Topics: Acute Disease; Adolescent; Anti-Bacterial Agents; Craniotomy; Diagnosis, Differential; Empyema, Subd | 2014 |
Suppurative intracranial complications of sinusitis in children.
Topics: Adolescent; Anti-Bacterial Agents; Ceftriaxone; Child; Empyema, Subdural; Humans; Male; Meningitis; | 2002 |
Subdural empyema due to spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anti-Bacterial Agents; Anti-Infective Agents; Brain; Ceftriaxone; Cesarea | 2005 |
Prevention of intracranial problems in ear and sinus surgery: a possible role for cefotaxime.
Topics: Bacteria; Brain Abscess; Cefotaxime; Chloramphenicol; Empyema, Subdural; Humans; Metronidazole; Micr | 1993 |
Subdural empyema caused by Prevotella loescheii with reduced susceptibility to metronidazole.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Drug Resistance, Microbial; Empyema, Subdural; Hum | 2001 |
Management of focal intracranial infections: is medical treatment better than surgery?
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Brain Abscess; Cause of Death; Ceftriaxone; Combined Modal | 1990 |
Drug therapy for intracranial suppuration.
Topics: Anti-Bacterial Agents; Brain Abscess; Cephalosporins; Empyema, Subdural; Humans; Metronidazole | 1988 |