metronidazole has been researched along with Abortion, Recurrent in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gay, C | 1 |
| Hamdaoui, N | 1 |
| Pauly, V | 1 |
| Rojat Habib, MC | 1 |
| Djemli, A | 1 |
| Carmassi, M | 1 |
| Chau, C | 1 |
| Bretelle, F | 1 |
| Dinglas, C | 1 |
| Chavez, M | 1 |
| Vintzileos, A | 1 |
2 other studies available for metronidazole and Abortion, Recurrent
| Article | Year |
|---|---|
Impact of antibiotic treatment for chronic endometritis on unexplained recurrent pregnancy loss.
Topics: Abortion, Habitual; Adult; Analysis of Variance; Anti-Bacterial Agents; Birth Rate; Chronic Disease; | 2021 |
Resolution of intra-amniotic sludge after antibiotic administration in a patient with short cervix and recurrent mid-trimester loss.
Topics: Abortion, Habitual; Adult; Anti-Bacterial Agents; Cerclage, Cervical; Cervix Uteri; Chorioamnionitis | 2019 |