Page last updated: 2024-10-31

metronidazole and Abortion, Recurrent

metronidazole has been researched along with Abortion, Recurrent in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Gay, C1
Hamdaoui, N1
Pauly, V1
Rojat Habib, MC1
Djemli, A1
Carmassi, M1
Chau, C1
Bretelle, F1
Dinglas, C1
Chavez, M1
Vintzileos, A1

Other Studies

2 other studies available for metronidazole and Abortion, Recurrent

ArticleYear
Impact of antibiotic treatment for chronic endometritis on unexplained recurrent pregnancy loss.
    Journal of gynecology obstetrics and human reproduction, 2021, Volume: 50, Issue:5

    Topics: Abortion, Habitual; Adult; Analysis of Variance; Anti-Bacterial Agents; Birth Rate; Chronic Disease;

2021
Resolution of intra-amniotic sludge after antibiotic administration in a patient with short cervix and recurrent mid-trimester loss.
    American journal of obstetrics and gynecology, 2019, Volume: 221, Issue:2

    Topics: Abortion, Habitual; Adult; Anti-Bacterial Agents; Cerclage, Cervical; Cervix Uteri; Chorioamnionitis

2019