metronidazole has been researched along with 6th Nerve Palsy in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lemierre's syndrome is characterized by acute oropharyngeal infection complicated by internal jugular venous thrombosis secondary to septic thrombophlebitis, and metastatic abscesses." | 2.43 | Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy. ( Jones, C; O'Reilly, BJ; Seymour, FK; Siva, TM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Etxeberria, A | 1 |
| Lonneville, S | 1 |
| Rutgers, MP | 1 |
| Gille, M | 1 |
| Jones, C | 1 |
| Siva, TM | 1 |
| Seymour, FK | 1 |
| O'Reilly, BJ | 1 |
1 review available for metronidazole and 6th Nerve Palsy
| Article | Year |
|---|---|
Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy.
Topics: Abducens Nerve Diseases; Adolescent; Anti-Bacterial Agents; Cefotaxime; Female; Follow-Up Studies; H | 2006 |
1 other study available for metronidazole and 6th Nerve Palsy
| Article | Year |
|---|---|
Metronidazole-cerebellopathy associated with peripheral neuropathy, downbeat nystagmus, and bilateral ocular abduction deficit.
Topics: Abducens Nerve Diseases; Accommodation, Ocular; Aged, 80 and over; Anti-Infective Agents; Cerebellar | 2012 |