metronidazole has been researched along with 2019 Novel Coronavirus Disease in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin resistance was higher (38." | 1.91 | Geographic distribution of antibiotic resistance of Helicobacter pylori: A study in Bulgaria. ( Boyanova, L; Gergova, G; Gergova, R; Kandilarov, N; Markovska, R; Yordanov, D, 2023) |
| "To date, knowledge on coronavirus disease 2019 (COVID-19) coinfection with enteric parasites is limited, and E." | 1.62 | Amoebic liver abscess in a COVID-19 patient: a case report. ( Camejo-Ávila, NA; Carballo, M; Carrión-Nessi, FS; Contreras, R; Escalante-Pérez, IA; Flora-Noda, DM; Forero-Peña, DA; Kuffaty-Akkou, NA; Landaeta, ME; Maricuto, AL; Noya-González, ÓO; Omaña-Ávila, ÓD; Pineda, J; Rodríguez, I; Rodríguez-Inés, CA; Velásquez, VL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 8 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maricuto, AL | 1 |
| Velásquez, VL | 1 |
| Pineda, J | 1 |
| Flora-Noda, DM | 1 |
| Rodríguez, I | 1 |
| Rodríguez-Inés, CA | 1 |
| Noya-González, ÓO | 1 |
| Contreras, R | 1 |
| Omaña-Ávila, ÓD | 1 |
| Escalante-Pérez, IA | 1 |
| Camejo-Ávila, NA | 1 |
| Kuffaty-Akkou, NA | 1 |
| Carrión-Nessi, FS | 1 |
| Carballo, M | 1 |
| Landaeta, ME | 1 |
| Forero-Peña, DA | 1 |
| Kamara, IF | 1 |
| Kumar, AMV | 1 |
| Maruta, A | 1 |
| Fofanah, BD | 1 |
| Njuguna, CK | 1 |
| Shongwe, S | 1 |
| Moses, F | 1 |
| Tengbe, SM | 1 |
| Kanu, JS | 1 |
| Lakoh, S | 1 |
| Mansaray, AHD | 1 |
| Selvaraj, K | 1 |
| Khogali, M | 1 |
| Zachariah, R | 1 |
| Farasati Far, B | 1 |
| Bokov, D | 1 |
| Widjaja, G | 1 |
| Setia Budi, H | 1 |
| Kamal Abdelbasset, W | 1 |
| Javanshir, S | 1 |
| Seif, F | 1 |
| Pazoki-Toroudi, H | 1 |
| Dey, SK | 1 |
| Mittal, H | 1 |
| Ivaturi, A | 1 |
| Khanuja, M | 1 |
| Boyanova, L | 2 |
| Gergova, G | 1 |
| Kandilarov, N | 1 |
| Yordanov, D | 1 |
| Gergova, R | 1 |
| Markovska, R | 1 |
| Bangar, S | 1 |
| Sonar, P | 1 |
| Mane, A | 1 |
| Sane, S | 1 |
| Kadam, A | 1 |
| Katendra, TL | 1 |
| Rahane, G | 1 |
| Sinha, A | 1 |
| Sahay, S | 1 |
| Duployez, C | 1 |
| Le Guern, R | 1 |
| Tinez, C | 1 |
| Lejeune, AL | 1 |
| Robriquet, L | 1 |
| Six, S | 1 |
| Loïez, C | 1 |
| Wallet, F | 1 |
| Lupia, T | 1 |
| Corcione, S | 1 |
| De Rosa, FG | 1 |
1 trial available for metronidazole and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Prevention of recurrence of bacterial vaginosis using lactobacilli-containing vaginal tablets among women with HIV: a randomized, placebo-controlled, double-blinded phase IV trial.
Topics: COVID-19; Female; HIV Infections; Humans; India; Lactobacillus; Metronidazole; Pandemics; Treatment | 2023 |
7 other studies available for metronidazole and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Amoebic liver abscess in a COVID-19 patient: a case report.
Topics: COVID-19; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; SA | 2021 |
Antibiotic Use in Suspected and Confirmed COVID-19 Patients Admitted to Health Facilities in Sierra Leone in 2020-2021: Practice Does Not Follow Policy.
Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; COVID-19; COVID-19 Drug Treatment; Cross-Sectional | 2022 |
Metronidazole, acyclovir and tetrahydrobiopterin may be promising to treat COVID-19 patients, through interaction with interleukin-12.
Topics: COVID-19; Cytokines; Humans; Interleukin-12; Metronidazole; Molecular Docking Simulation | 2023 |
MoSe
Topics: Anti-Bacterial Agents; Catalysis; COVID-19; COVID-19 Drug Treatment; Humans; Metronidazole; Nanocomp | 2023 |
Geographic distribution of antibiotic resistance of Helicobacter pylori: A study in Bulgaria.
Topics: Amoxicillin; Anti-Bacterial Agents; Bulgaria; Clarithromycin; COVID-19; Drug Resistance, Bacterial; | 2023 |
Panton-Valentine Leukocidin-Secreting Staphylococcus aureus Pneumonia Complicating COVID-19.
Topics: Adult; Anti-Bacterial Agents; Bacterial Toxins; Betacoronavirus; Cefotaxime; Clindamycin; Clinical L | 2020 |
Giardiasis reactivation during severe SARS-CoV-2 infection.
Topics: Aged; Antiprotozoal Agents; COVID-19; Giardiasis; Humans; Latent Infection; Male; Metronidazole; SAR | 2021 |