metrizamide and Meningioma

Topics: Brain Diseases; Brain Neoplasms; Cerebral Hemorrhage; Contrast Media; False Positive Reactions; Humans; Intracranial Arteriovenous Malformations; Ischemic Attack, Transient; Meningeal Neoplasms; Meningioma; Metrizamide; Tomography, X-Ray Computed

Computed tomography (CT) is currently the primary and generally the definitive imaging modality for the diagnosis, evaluation, and management of intracranial neoplasms in children. The value of CT in the postoperative period is discussed. The role of CT and myelography is stressed in the evaluation of cerebrospinal fluid seeding. CT is also important in demonstrating the iatrogenic disturbances of the central nervous system as a result of radiation and chemotherapy. The authors recommend that CT scans with and without contrast be obtained 2 weeks after surgery and before starting any form of adjuvant treatment. CT slices should be contiguous and 5-mm thick. Subsequent scans should be obtained every 3 to 4 months for the first year and every 6 months thereafter. Where necessary, CT scans after the introduction of intrathecal metrizamide may be necessary to evaluate the lower portion of the posterior fossa and brain stem.

Topics: Adolescent; Astrocytoma; Brain Neoplasms; Cerebral Ventricle Neoplasms; Child; Female; Glioma; Humans; Infant; Male; Meningeal Neoplasms; Meningioma; Metrizamide; Myelography; Neoplasm Seeding; Spinal Cord Neoplasms; Tomography, X-Ray Computed

Meningiomas seldom occur in children, and spinal meningioma in a child is rare. We report the case of a boy, 3 years and 5 months of age, who had an unusual atypical meningioma involving the subarachnoid space from T-2 to the cauda equina. To our knowledge, no similar case has been reported previously.

Topics: Child, Preschool; Combined Modality Therapy; Dexamethasone; Humans; Laminectomy; Male; Meningioma; Metrizamide; Myelography; Spinal Neoplasms; Subarachnoid Space; Tomography, X-Ray Computed

Topics: Contrast Media; Ependymoma; Humans; Iopamidol; Iothalamic Acid; Meningeal Neoplasms; Meningioma; Metrizamide; Myelography; Spinal Cord Diseases; Spinal Cord Neoplasms; Spinal Diseases

The radiological manifestations of 16 pituitary adenomas, six meningiomas and 14 craniopharyngiomas were reviewed. The differential diagnosis of these tumors is possible with a few exceptions when skull radiography, CT, angiography and metrizamide cisternography are carefully evaluated. Prolonged injection angiography (PIA) is particularly important for demonstrating the contours of pituitary adenomas and meningiomas. Metrizamide cisternography is indicated when the tumor contours are obscure using PIA, or when the differential diagnosis is uncertain.

Topics: Adenoma; Cerebral Angiography; Cisterna Magna; Craniopharyngioma; Diagnosis, Differential; Humans; Meningeal Neoplasms; Meningioma; Metrizamide; Pituitary Neoplasms; Skull; Tomography, X-Ray Computed

Either EMT Head Scanner, CT 1010 (slice thickness 10mm) or EMI Body Scanner, CT 5005 (slice thickness 13mm) was used. The concentration of metrizamide was 170-250 mgI/microliter and the amount was 7-10 microliters. Either lumbar puncture or lateral C puncture was made.. 26 cases were included in this study. 1) disc disease: 11 cases, 2) spinal cord tumor: 6 cases, 3) Arnold-Chiari malformation: 3 cases, 4) atlantoaxial dislocation: 3 cases, 5) ossification of the posterior longitudinal ligament (associated with ossification of the ligamentum flavum): 2 cases (1 case), 6) spinal foreign body (acupuncture needle): 1 case.. 1) CT metrizamide myelography visualizes the subarachnoid space and makes it possible to know the lesion in the spinal canal in relation to the spinal cord in transverse plane. 2) It is difficult to determine the exact level of the lesion in axial plane. 3) The present technique does not allow to visualize the root sleeves. 4) It is difficult to delineate a compression of the subarachnoid space by small localized lesions (esp., disc diseases) due to overlapping the patent adjacent subarachnoid space within a slice 10 mm to 13 mm thick.

Topics: Astrocytoma; Humans; Meningeal Neoplasms; Meningioma; Metrizamide; Myelography; Neurilemmoma; Spinal Cord Neoplasms; Spinal Diseases; Tomography, X-Ray Computed

Metrizamide computerized tomographic cisternography was performed with a small dose and low concentration of intrathecal metrizamide using a newer generation of computerized tomography scanner for the evaluation of sellar and suprasellar abnormalities. The examination was performed with thin sections in axial, direct coronal, and (when feasible) direct sagittal projections in a high-resolution technique. The relationship of the lesions with carotid arteries, optic chiasms, and hypothalamic structures was accurately defined.

Topics: Adenoma; Adenoma, Chromophobe; Adolescent; Adult; Cranial Nerve Neoplasms; Empty Sella Syndrome; Female; Humans; Male; Meningioma; Metrizamide; Middle Aged; Myelography; Optic Chiasm; Pituitary Diseases; Pituitary Neoplasms; Sella Turcica; Tomography, X-Ray Computed

Topics: Astrocytoma; Humans; Lipoma; Meningeal Neoplasms; Meningioma; Metrizamide; Myelography; Neurilemmoma; Radiographic Image Enhancement; Spinal Cord Neoplasms; Tomography, X-Ray Computed

Topics: Astrocytoma; Chondroma; Hemangioma; Humans; Medulloblastoma; Meningioma; Metrizamide; Neurofibromatosis 1; Spinal Cord Neoplasms; Tomography, X-Ray Computed

Twenty-three cases suspected of skull base tumors were examined by CT cisternography (CTC) with CT scanner (EMI 1010) from April, 1977 to March, 1978. The lesions in 20 cases were diagnosed as positive and confirmed by operation and/or autopsies. These include five acoustic neurinomas, six pituitary adenomas, two craniopharyngiomas, two skull base meningiomas, one arachnoid cyst and miscellaneous tumors. Isotonic Metrizamide solution four of 2-10 ml was injected via lumbar route. Patients were kept in 30 degrees Trendelenburg position for 60 minutes until the first scanning. Scannings were obtained 1, 3, 6, 24 and in some cases 48 hours after lumbar injection. No side effects except for headache, nausea, vomiting occurred. There were no convulsions. In diagnosing cerebellopontine angle tumors, the indirect signs such as asymmetrical ambient cisterns are of importance, when combined with direct signs, i.e. a shadow defect. Parasellar tumors are usually difficult to diagnose with conventional CT due to streak artifact caused by adjacent bony structure. In CTC the extrasellar extension of pituitary tumors were clearly visible. The size, shape, dimensions and the relationship to the adjacent structures of the craniopharyngiomas were easily demonstrated with CTC especially when a coronal view was added. In arachnoid cyst, CTC demonstrated the delayed turnover of Metrizamide between the cyst cavity and the adjacent subarachnoid space. In conclusion, CTC is an useful neuroradiological diagnostic adjunct because of minimal bony streak artifact and high spatial resolution. It would be expected that small tumors of even 2-3 mm in diameter might be diagnosed, from the fact that the middle cerebral artery in the suprasellar cistern is clearly visible as a shadow defect.

Topics: Brain Neoplasms; Child; Cisterna Magna; Craniopharyngioma; Female; Humans; Meningeal Neoplasms; Meningioma; Metrizamide; Middle Aged; Neuroma, Acoustic; Tomography, X-Ray Computed

The subarachnoid space continues into the orbit as part of the optic nerve sheath. This space varies in size but is usually tiny. Occasionally, prominent (one case in our experience) enhancement of the optic nerve as part of metrizamide computed tomography (CT) cisternography is seen on transverse and coronal scans presumably because of a patulous optic subarachnoid space. In five cases, we have appreciated minimal enhancement of optic nerves with metrizamide only by close comparison of CT numbers with base-line scans. One of these patients had a tiny meningioma removed successfully from the optic sheath, with return to normal vision of a previously blind eye.

Topics: Adult; Cerebrospinal Fluid Rhinorrhea; Cranial Nerve Neoplasms; Female; Humans; Injections, Spinal; Meningioma; Metrizamide; Middle Aged; Optic Nerve; Optic Nerve Diseases; Radiographic Image Enhancement; Tomography, X-Ray Computed

The technique and results of cerebello-pontine angle cisternography with metrizamide (Amipaque) in 34 patients are reported. Fourteen tumors were diagnosed. The internal auditory canal was normal in 19 patients, and in all of them the facial and statoacoustic nerves were visible. One examination was unsuccessful. No serious complications occurred. Headache was recorded in 76 per cent and transient EEG disturbance in 32 per cent of the patients.

Topics: Adult; Aged; Cerebellar Neoplasms; Cerebellopontine Angle; Cholesteatoma; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Metrizamide; Middle Aged; Myelography; Neuroma, Acoustic

Topics: Brain Neoplasms; Cerebral Aqueduct; Cerebrospinal Fluid; Cysts; Humans; Hydrocephalus; Intracranial Pressure; Meningioma; Metrizamide; Papilloma; Subarachnoid Space; Tomography, X-Ray Computed