metrizamide and Constriction--Pathologic

The most unpleasant side effect of peripheral angiography is an intense pain and a burning sensation following the injection of the contrast material. It was recently shown (1) that the use of a non-ionic and less hypertonic contrast medium (metrizamide) in femoral angiography was associated with less pain when compared to an ionic medium (metrizoate). We thought it therefore advisable to perform foot angiography with such a non-ionic contrast medium (Amipaque, Nyegaard & Co, Oslo, Norway) in 9 diabetic patients with soft tissue and skeletal lesions of the foot. The angiographic examination was considered valuable for planning of therapy and predicting the prognosis. The results of the examinations are illustrated and discussed with regard to visualization of the digital arteries, subjective reactions to the angiographic examination and relationship of the vascular findings to soft tissue and skeletal lesions. It is stated that foot angiography performed with a non-ionic contrast medium is painless and allows contrast filling of the most peripheral digital arterial branches. On the basis of the angiographic findings the gangrenous lesions were categorized as ischemic or non-ischemic.

Topics: Aged; Angiography; Bone Diseases; Constriction, Pathologic; Diabetes Complications; Diabetic Angiopathies; Female; Foot; Gangrene; Humans; Male; Metrizamide; Middle Aged; Necrosis

The results are reported of lumbar epidurography in 110 patients suffering from low back pain. By using the water-soluble non-ionic contrast metrizamide, it has been possible to perform the examination on an outpatient basis. None of the patients has suffered from headache, nor any other complaint often associated with other diagnostic techniques which involve lumbar puncture. Epidurography is sufficiently accurate to be regarded as the examination of choice in the diagnosis of lumbar disc prolapse.

Topics: Constriction, Pathologic; Epidural Space; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Metrizamide; Radiography; Spinal Canal

Topical diagnostic problems in cases of chronic cervical myelopathy in correlation with cervical spinal stenosis are pointed out. The importance for technically perfect myelography with Amipaque in order to enable thorough and most precise diagnosis is stressed.

Topics: Cervical Vertebrae; Constriction, Pathologic; Humans; Metrizamide; Myelography; Spinal Cord Compression; Spinal Diseases

Seventeen cases with (obstructive) lesions in the region of the tentorial hiatus were examined with an EMI CT 1010 brain scanner, of which 8 had additional intrathecal metrizamide. Findings were compared with information received from angiographic studies and conventional contrast examinations of the intracranial CSF spaces and with CT scans of patients presenting with herniation at the tentorial hiatus. CT, including enhancement and intrathecal metrizamide, did not yield optimal information about exact localisation or infiltrative growth of lesions. A combination with conventional procedures was needed in order to obtain essential information.

Topics: Brain Neoplasms; Cerebellar Diseases; Cerebral Angiography; Cerebral Aqueduct; Cerebral Ventriculography; Constriction, Pathologic; Humans; Metrizamide; Radionuclide Imaging; Tomography, X-Ray Computed