metribolone and Mouth-Neoplasms

metribolone has been researched along with Mouth-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for metribolone and Mouth-Neoplasms

ArticleYear
Androgen and progesterone receptors in oral carcinoma.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 1994, Volume: 22, Issue:2

    Androgen (AR) and progesterone (PgR) receptors were measured in 18 samples of normal oral mucosa and of squamous cell carcinoma of the floor of the mouth or the tongue. In a given mean concentration of R1881 (Methyltrienolone) of 8.4 nM in the carcinoma and of 7.9 nM in the normal mucosa, we measured a mean androgen receptor level in the carcinoma smaller than 1.08 fmol/mg protein (< 0.034 fmol/microgram DNA). There was a significant difference (p < 0.05) from the androgen receptor level in the normal mucosa (2.2 fmol/mg protein, 0.082 fmol/microgram DNA). In this experiment, in only 41.2% did we find any PgR receptor in the carcinoma whereas all normal tissue contained PgR, the concentration varied between 0.1 and 3.0 fmol/mg protein (0.01-0.09 fmol/microgram DNA).

    Topics: Aged; Carcinoma, Squamous Cell; Dihydrotestosterone; DNA, Neoplasm; Female; Humans; Male; Metribolone; Middle Aged; Mouth Floor; Mouth Mucosa; Mouth Neoplasms; Neoplasm Proteins; Receptors, Androgen; Receptors, Progesterone; Tongue Neoplasms; Triamcinolone Acetonide; Tritium

1994