metoprolol has been researched along with Syncope in 36 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intravenous metoprolol was found to be significantly more effective than placebo in preventing head-up tilt-table induced neurally mediated syncope." | 9.08 | Usefulness of intravenous metoprolol to prevent syncope induced by head-up tilt. ( Azar, P; Bazunga, M; Chow, MS; Goldman, R; Kluger, J; O'Rangers, E, 1998) |
| " To unmask the potential risk of Tdp in a patient with normal or borderline prolongation of QTc interval and recurrent syncope, dobutamine was given intravenously at a rate of 20 microg/kg/min." | 7.75 | Dobutamine infusion for unmasking long QT syndrome and torsades de pointes. ( Cuilan, L; Dayi, H; Kangan, C; Peng, G; Quan, F; Richard, CC, 2009) |
| "We conclude that metoprolol is safe and effective for the treatment of most cases of neurocardiogenic syncope in children and that this response cannot be predicted accurately by the use of intravenous metoprolol during testing." | 7.69 | Tilt-table testing and oral metoprolol therapy in young patients with unexplained syncope. ( MacLellan-Tobert, SG; O'Marcaigh, AS; Porter, CJ, 1994) |
| "The efficacy of intravenous metoprolol in preventing symptoms during a repeat tilt test was compared with the outcome of chronic oral treatment in 21 patients (14 female, 7 male), age 8 to 20 years (mean 13 +/- 3) with unexplained syncope (> or = 1 episode) and a positive response to tilt testing." | 7.68 | Usefulness of metoprolol for unexplained syncope and positive response to tilt testing in young persons. ( Benson, DW; Deal, BJ; Müller, G; Strasburger, JF, 1993) |
| "The usefulness of esmolol in predicting the efficacy of treatment with an oral beta-adrenergic blocking agent was evaluated in 27 consecutive patients with neurocardiogenic syncope." | 7.68 | Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope. ( Akhtar, M; Avitall, B; Jazayeri, MR; Murthy, VS; Shen, YH; Sra, JS; Troup, PJ, 1992) |
| "The 3-dimensional CPF is simple, easy to use, stable over time, measures 3 independent variables, and documents that metoprolol does not reduce presyncope." | 5.14 | Design and use of a quantitative scale for measuring presyncope. ( Amuah, JE; Connolly, SJ; Fouad-Tarazi, F; Klingenheben, T; Koshman, ML; Krahn, AD; Kus, T; Morillo, CA; Ritchie, D; Rose, S; Sheldon, A; Sheldon, RS; Talajic, M, 2009) |
| "Intravenous metoprolol was found to be significantly more effective than placebo in preventing head-up tilt-table induced neurally mediated syncope." | 5.08 | Usefulness of intravenous metoprolol to prevent syncope induced by head-up tilt. ( Azar, P; Bazunga, M; Chow, MS; Goldman, R; Kluger, J; O'Rangers, E, 1998) |
| " To unmask the potential risk of Tdp in a patient with normal or borderline prolongation of QTc interval and recurrent syncope, dobutamine was given intravenously at a rate of 20 microg/kg/min." | 3.75 | Dobutamine infusion for unmasking long QT syndrome and torsades de pointes. ( Cuilan, L; Dayi, H; Kangan, C; Peng, G; Quan, F; Richard, CC, 2009) |
| "To examine hemodynamic, plasma catecholamines, and cyclic AMP changes during tilt in patients with neurocardiogenic (vasodepressor) syncope, six patients underwent 80 degrees head-up tilt test for 10 minutes with isoproterenol infusion (1-3 micrograms/min)." | 3.69 | Plasma catecholamines and cyclic AMP response during head-up tilt test in patients with neurocardiogenic (vasodepressor) syncope. ( Abe, H; Izumi, F; Kobayashi, H; Kuroiwa, A; Nakashima, Y, 1995) |
| "We conclude that metoprolol is safe and effective for the treatment of most cases of neurocardiogenic syncope in children and that this response cannot be predicted accurately by the use of intravenous metoprolol during testing." | 3.69 | Tilt-table testing and oral metoprolol therapy in young patients with unexplained syncope. ( MacLellan-Tobert, SG; O'Marcaigh, AS; Porter, CJ, 1994) |
| "Seventy consecutive patients with recurrent unexplained syncope were evaluated by use of an up-right tilt-table test for 45 minutes (with or without an infusion of isoproterenol) in an attempt to reproduce symptoms." | 3.68 | [Malignant vasovagal syncope: its diagnosis and therapeutic trial based on the orthostatism test (the tilt-table test)]. ( Campos Peris, JV; de la Morena, G; García García, J; Jaén Armand, E; López Candel, J; Martínez Sánchez, J; Picó Aracil, F; Ruiz Ros, JA; Salas, J; Sánchez Muñoz, JJ, 1993) |
| "The efficacy of intravenous metoprolol in preventing symptoms during a repeat tilt test was compared with the outcome of chronic oral treatment in 21 patients (14 female, 7 male), age 8 to 20 years (mean 13 +/- 3) with unexplained syncope (> or = 1 episode) and a positive response to tilt testing." | 3.68 | Usefulness of metoprolol for unexplained syncope and positive response to tilt testing in young persons. ( Benson, DW; Deal, BJ; Müller, G; Strasburger, JF, 1993) |
| "The usefulness of esmolol in predicting the efficacy of treatment with an oral beta-adrenergic blocking agent was evaluated in 27 consecutive patients with neurocardiogenic syncope." | 3.68 | Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope. ( Akhtar, M; Avitall, B; Jazayeri, MR; Murthy, VS; Shen, YH; Sra, JS; Troup, PJ, 1992) |
| "During evaluation for palpitations, presyncope, or syncope, seven pregnant women had documented ventricular tachycardia." | 2.38 | New-onset ventricular tachycardia during pregnancy. ( Allen, B; Brodsky, M; Doria, R; Sada, M; Sato, D; Thomas, G, 1992) |
| "Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but potentially lethal inherited arrhythmia syndrome induced by adrenergic stress." | 1.48 | A delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia with a mutant of RYR2 at c.7580T>G for 6 years in a 9-year-old child. ( Duan, H; Hua, Y; Li, Y; Lu, Y; Qiao, L; Wang, C; Yan, S; Zhou, K, 2018) |
| "Catecholaminergic polymorphic ventricular tachycardia was diagnosed with the aid of an implantable loop recorder." | 1.39 | A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia. ( Anastasakis, A; Kotsaka, X; Luria, D; Mantziari, L; Paraskevaidis, S; Styliadis, IH; Vassilikos, V, 2013) |
| "Syncope was induced during baseline head-up tilt in nine patients (group III) and after isoproterenol challenge in five (group IV)." | 1.28 | Echocardiographic demonstration of decreased left ventricular dimensions and vigorous myocardial contraction during syncope induced by head-up tilt. ( Akhtar, M; Anderson, AJ; Avitall, B; Gal, R; Jazayeri, MR; Shalev, Y; Tchou, PJ, 1991) |
| " Beta blockade was obtained by infusing metoprolol intravenously at a dosage of 0." | 1.27 | [Influence of beta block and autonomic nerve block on the recovery time of the sinus node in sick sinus syndrome and carotid sinus syndrome]. ( Barra, M; Bertulla, A; Brignole, M; Menozzi, C; Monducci, I; Sartore, B, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 18 (50.00) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 10 (27.78) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bottigliero, D | 1 |
| Monaco, I | 1 |
| Santacroce, R | 1 |
| Casavecchia, G | 1 |
| Correale, M | 1 |
| Guastafierro, F | 1 |
| Leccese, A | 1 |
| Cordisco, G | 1 |
| Ieva, R | 1 |
| Trunzo, R | 1 |
| Di Biase, M | 1 |
| Margaglione, M | 1 |
| Brunetti, ND | 1 |
| Mahowald, MK | 1 |
| Fender, EA | 1 |
| Prasad, A | 1 |
| Nishimura, RA | 1 |
| Muniyappa, A | 1 |
| Goldschlager, N | 1 |
| Carroll, C | 1 |
| Hassanin, A | 1 |
| Velibey, Y | 1 |
| Yaylak, B | 1 |
| Guvenc, TS | 1 |
| Cinier, G | 1 |
| Kalenderoglu, K | 1 |
| Guzelburc, O | 1 |
| Yildirimturk, O | 1 |
| Duan, H | 1 |
| Lu, Y | 1 |
| Yan, S | 1 |
| Qiao, L | 1 |
| Hua, Y | 1 |
| Li, Y | 1 |
| Zhou, K | 1 |
| Wang, C | 1 |
| Mantziari, L | 1 |
| Vassilikos, V | 1 |
| Anastasakis, A | 1 |
| Kotsaka, X | 1 |
| Paraskevaidis, S | 1 |
| Styliadis, IH | 1 |
| Luria, D | 1 |
| Schroeder, C | 1 |
| Heusser, K | 1 |
| Zoerner, AA | 1 |
| Großhennig, A | 1 |
| Wenzel, D | 1 |
| May, M | 1 |
| Sweep, FC | 1 |
| Mehling, H | 1 |
| Luft, FC | 1 |
| Tank, J | 1 |
| Jordan, J | 2 |
| Abu-Zeitone, A | 1 |
| Peterson, DR | 1 |
| Polonsky, B | 1 |
| McNitt, S | 1 |
| Moss, AJ | 1 |
| Tagawa, M | 1 |
| Ochiai, S | 1 |
| Nakamura, Y | 1 |
| Sato, A | 1 |
| Chinushi, M | 1 |
| Meena, DS | 1 |
| Meena, CB | 1 |
| Parvez, J | 1 |
| Quan, F | 1 |
| Peng, G | 1 |
| Kangan, C | 1 |
| Dayi, H | 1 |
| Cuilan, L | 1 |
| Richard, CC | 1 |
| Sheldon, RS | 1 |
| Amuah, JE | 1 |
| Connolly, SJ | 1 |
| Rose, S | 1 |
| Morillo, CA | 1 |
| Talajic, M | 1 |
| Kus, T | 1 |
| Fouad-Tarazi, F | 1 |
| Klingenheben, T | 1 |
| Krahn, AD | 1 |
| Sheldon, A | 1 |
| Koshman, ML | 1 |
| Ritchie, D | 1 |
| Binder, WD | 1 |
| Fifer, MA | 1 |
| King, ME | 1 |
| Stone, JR | 1 |
| Jacobs, A | 1 |
| Knight, BP | 1 |
| McDonald, KT | 1 |
| Burke, MC | 1 |
| Thürmann, PA | 1 |
| Haack, S | 1 |
| Werner, U | 1 |
| Szymanski, J | 1 |
| Haase, G | 1 |
| Drewelow, B | 1 |
| Reimann, IR | 1 |
| Hippius, M | 1 |
| Siegmund, W | 1 |
| May, K | 1 |
| Hasford, J | 1 |
| Brignole, M | 1 |
| Sartore, B | 1 |
| Barra, M | 1 |
| Menozzi, C | 1 |
| Monducci, I | 1 |
| Bertulla, A | 1 |
| Abe, H | 2 |
| Kobayashi, H | 2 |
| Nakashima, Y | 2 |
| Izumi, F | 2 |
| Kuroiwa, A | 2 |
| Grubb, BP | 1 |
| Kosinski, D | 1 |
| Samoil, D | 1 |
| Pothoulakis, A | 1 |
| Lorton, M | 1 |
| Kip, K | 1 |
| Sneddon, JF | 1 |
| Scalia, G | 1 |
| Ward, DE | 1 |
| McKenna, WJ | 1 |
| Camm, AJ | 1 |
| Frenneaux, MP | 1 |
| O'Marcaigh, AS | 1 |
| MacLellan-Tobert, SG | 1 |
| Porter, CJ | 1 |
| López Candel, J | 1 |
| Picó Aracil, F | 1 |
| Sánchez Muñoz, JJ | 1 |
| de la Morena, G | 1 |
| Martínez Sánchez, J | 1 |
| Salas, J | 1 |
| Campos Peris, JV | 1 |
| Ruiz Ros, JA | 1 |
| García García, J | 1 |
| Jaén Armand, E | 1 |
| Müller, G | 1 |
| Deal, BJ | 1 |
| Strasburger, JF | 1 |
| Benson, DW | 1 |
| Sra, JS | 2 |
| Jazayeri, MR | 3 |
| Avitall, B | 3 |
| Dhala, A | 1 |
| Deshpande, S | 1 |
| Blanck, Z | 1 |
| Akhtar, M | 3 |
| Jhamb, DK | 1 |
| Singh, B | 1 |
| Sharda, B | 1 |
| Kaul, U | 1 |
| Goel, P | 1 |
| Talwar, KK | 1 |
| Wasir, HS | 1 |
| Pucciarelli, G | 1 |
| De Vecchis, R | 1 |
| Ebraio, F | 1 |
| Corigliano, GG | 1 |
| Hirata, K | 1 |
| Takagi, Y | 1 |
| Nakada, M | 1 |
| Kyushima, M | 1 |
| Asato, H | 1 |
| Kluger, J | 1 |
| Bazunga, M | 1 |
| Goldman, R | 1 |
| O'Rangers, E | 1 |
| Azar, P | 1 |
| Chow, MS | 1 |
| Murthy, VS | 1 |
| Shen, YH | 1 |
| Troup, PJ | 1 |
| Dangovian, MI | 1 |
| Jarandilla, R | 1 |
| Frumin, H | 1 |
| Brodsky, M | 1 |
| Doria, R | 1 |
| Allen, B | 1 |
| Sato, D | 1 |
| Thomas, G | 1 |
| Sada, M | 1 |
| Shalev, Y | 1 |
| Gal, R | 1 |
| Tchou, PJ | 1 |
| Anderson, AJ | 1 |
| Kinney, RO | 1 |
| Stäblein, A | 1 |
| Huber, I | 1 |
| von Scheidt, W | 1 |
3 reviews available for metoprolol and Syncope
| Article | Year |
|---|---|
Novel AKAP9 mutation and long QT syndrome in a patient with torsades des pointes.
Topics: A Kinase Anchor Proteins; Aged, 80 and over; Cytoskeletal Proteins; Echocardiography, Doppler; Elect | 2019 |
Hypertrophic obstructive cardiomyopathy with multiple coronary arteries to right ventricular microfistulas: a case report and review of the literature.
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Coronary Angiography; | 2017 |
New-onset ventricular tachycardia during pregnancy.
Topics: Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follo | 1992 |
6 trials available for metoprolol and Syncope
| Article | Year |
|---|---|
Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Benzazepines; Blood Pr | 2014 |
Design and use of a quantitative scale for measuring presyncope.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Me | 2009 |
Effects of beta-adrenergic blockade on vasodepressor reaction in patients with vasodepressor syncope.
Topics: Epinephrine; Erythrocyte Membrane; Female; Humans; Isoproterenol; Male; Metoprolol; Middle Aged; Nor | 1994 |
Comparative study of the efficacy of metoprolol and verapamil in patients with syncope and positive head-up tilt test response.
Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Female; Heart | 1996 |
[Vasovagal syncope and increased baroreceptor activity: evidence for increased sensibility of the baroreflex and its rapid reversal with acute administration of metoprolol].
Topics: Adult; Anti-Arrhythmia Agents; Baroreflex; Case-Control Studies; Female; Humans; Male; Metoprolol; M | 1997 |
Usefulness of intravenous metoprolol to prevent syncope induced by head-up tilt.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure Monitoring, Ambulatory; Double-Blind Method | 1998 |
27 other studies available for metoprolol and Syncope
| Article | Year |
|---|---|
Exertional Syncope in an Athlete: The Answer is in the History and Exam.
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Athletes; Cardiomyopathy, Hypertrophic; Echocardio | 2020 |
Wide Complex Ventricular Rhythm in a Patient After Collapse.
Topics: Aged, 80 and over; Antihypertensive Agents; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; | 2017 |
Polypharmacy in the Elderly-When Good Drugs Lead to Bad Outcomes: A Teachable Moment.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Antihypertensive Agents; Atorvastatin; Atrial Fibrillatio | 2017 |
Inadvertent Left Ventricle Endocardial or Uncomplicated Right Ventricular Pacing: How to Differentiate in the Emergency Department.
Topics: Aged; Anticoagulants; Antihypertensive Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Diag | 2018 |
A delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia with a mutant of RYR2 at c.7580T>G for 6 years in a 9-year-old child.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Death, Sudden, Cardiac; Delayed Diagnosis; Electrocardiog | 2018 |
A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia.
Topics: Adolescent; Anti-Arrhythmia Agents; Defibrillators, Implantable; Female; Flecainide; Follow-Up Studi | 2013 |
Efficacy of different beta-blockers in the treatment of long QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Death, Sudden, Ca | 2014 |
Secondly ECG recordings in the emergency room revealed Garenoxacin-induced abnormal QT interval prolongation in a patient with multiple syncopal attacks.
Topics: Adrenergic Agonists; Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Bacterial Agents; Electrocar | 2016 |
Dobutamine infusion for unmasking long QT syndrome and torsades de pointes.
Topics: Adrenergic beta-Agonists; Anti-Arrhythmia Agents; Defibrillators, Implantable; DNA Mutational Analys | 2009 |
Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging.
Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Diagnosis, Differentia | 2005 |
More reasons doing less in syncope patients.
Topics: Aged; Antihypertensive Agents; Carotid Sinus; Diterpenes; Female; Humans; Male; Massage; Metoprolol; | 2006 |
Verapamil decreases ventricular tachyarrhythmias in a patient with Timothy syndrome (LQT8).
Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Combined Modality Therapy; Defibrillat | 2006 |
Tolerability of beta-blockers metabolized via cytochrome P450 2D6 is sex-dependent.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bradycardia; Cytochrome P-450 CYP2D6; Dose-Res | 2006 |
[Influence of beta block and autonomic nerve block on the recovery time of the sinus node in sick sinus syndrome and carotid sinus syndrome].
Topics: Adult; Aged; Atropine; Autonomic Nerve Block; Carotid Sinus; Female; Heart Rate; Humans; Male; Metop | 1984 |
Plasma catecholamines and cyclic AMP response during head-up tilt test in patients with neurocardiogenic (vasodepressor) syncope.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; | 1995 |
Postpartum syncope.
Topics: 1-Naphthylamine; Administration, Oral; Adolescent; Adult; Diagnosis, Differential; Disopyramide; Dos | 1995 |
Exercise induced vasodepressor syncope.
Topics: Adolescent; Adult; Aged; Cardiac Output; Disopyramide; Exercise; Exercise Test; Female; Heart Rate; | 1994 |
Tilt-table testing and oral metoprolol therapy in young patients with unexplained syncope.
Topics: Administration, Oral; Adolescent; Blood Pressure; Child; Female; Heart Rate; Humans; Isoproterenol; | 1994 |
[Malignant vasovagal syncope: its diagnosis and therapeutic trial based on the orthostatism test (the tilt-table test)].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Clonidine; Female; Heart Functio | 1993 |
Usefulness of metoprolol for unexplained syncope and positive response to tilt testing in young persons.
Topics: Administration, Oral; Adolescent; Adult; Child; Female; Follow-Up Studies; Humans; Injections, Intra | 1993 |
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up St | 1993 |
Beat-to-beat variation of the ST segment in a patient with right bundle branch block, persistent ST segment elevation, and ventricular fibrillation: a case report.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electric Countershock; Electrocardiography; Hear | 1998 |
Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Female; Humans; Hypotension, Orthostatic; Isoprot | 1992 |
Prolonged asystole during head-up tilt table testing after beta blockade.
Topics: Adrenergic beta-Antagonists; Adult; Bradycardia; Female; Heart Arrest; Humans; Hypotension, Orthosta | 1992 |
Echocardiographic demonstration of decreased left ventricular dimensions and vigorous myocardial contraction during syncope induced by head-up tilt.
Topics: Adult; Echocardiography; Female; Humans; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Po | 1991 |
Cardiac arrest in an on-call intern.
Topics: Adult; Heart Arrest; Humans; Hypotension, Orthostatic; Male; Metoprolol; Syncope | 1991 |
[Life threatening syncope in a 69-year-old male: syndrome of hyperactive parasympathetic counter-regulation].
Topics: Aged; Cardiomyopathy, Hypertrophic; Cerebral Hemorrhage; Hemodynamics; Homeostasis; Humans; Isoprote | 1990 |