metoprolol has been researched along with Sleep Apnea, Obstructive in 5 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigated the roles of metoprolol in regulation of atrial remodeling induced by chronic OSA." | 7.85 | Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria. ( Dong, X; Li, H; Li, M; Li, Y; Lu, S; Sun, L; Wang, X; Wang, Y; Yan, S; Yu, S; Zhao, J; Zhao, S, 2017) |
| "Metoprolol protects against chronic OSA-induced cardiac apoptosis and fibrosis in left ventricular myocytes of canines, which may provide new potential strategy for drug therapy of OSA." | 7.81 | Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea. ( Ding, X; Li, H; Li, W; Li, Y; Liu, L; Liu, Z; Peng, W; Wang, D; Yan, S; Zhang, S; Zhao, J, 2015) |
| "Background Whether chronic obstructive sleep apnea ( OSA ) could promote epicardial adipose tissue ( EAT ) secretion of profibrotic adipokines, and thereby contribute to atrial fibrosis, and the potential therapeutic effects of metoprolol remain unknown." | 3.91 | Metoprolol Inhibits Profibrotic Remodeling of Epicardial Adipose Tissue in a Canine Model of Chronic Obstructive Sleep Apnea. ( Dai, H; Gong, Y; Han, Y; Li, T; Li, Y; Sheng, L; Sun, L; Xu, J; Yin, S; Yuan, Y; Zhang, Y, 2019) |
| " Here, we investigated the roles of metoprolol in regulation of atrial remodeling induced by chronic OSA." | 3.85 | Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria. ( Dong, X; Li, H; Li, M; Li, Y; Lu, S; Sun, L; Wang, X; Wang, Y; Yan, S; Yu, S; Zhao, J; Zhao, S, 2017) |
| "Metoprolol protects against chronic OSA-induced cardiac apoptosis and fibrosis in left ventricular myocytes of canines, which may provide new potential strategy for drug therapy of OSA." | 3.81 | Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea. ( Ding, X; Li, H; Li, W; Li, Y; Liu, L; Liu, Z; Peng, W; Wang, D; Yan, S; Zhang, S; Zhao, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, L | 1 |
| Zhao, J | 3 |
| Qu, Y | 1 |
| Sun, Q | 1 |
| Li, TT | 1 |
| Yan, ML | 1 |
| Duan, MJ | 1 |
| Li, KX | 1 |
| Wang, YR | 1 |
| Huang, SY | 1 |
| Zhang, S | 2 |
| Li, Y | 5 |
| Ai, J | 1 |
| Sun, L | 2 |
| Yan, S | 2 |
| Wang, X | 1 |
| Zhao, S | 1 |
| Li, H | 2 |
| Wang, Y | 1 |
| Lu, S | 1 |
| Dong, X | 1 |
| Yu, S | 1 |
| Li, M | 1 |
| Shi, J | 1 |
| Yuan, Y | 2 |
| Deng, X | 1 |
| Pan, Y | 1 |
| He, M | 1 |
| Liu, G | 1 |
| Sun, D | 1 |
| Wang, J | 1 |
| Wang, W | 1 |
| Dai, H | 1 |
| Yin, S | 1 |
| Zhang, Y | 1 |
| Han, Y | 1 |
| Li, T | 1 |
| Xu, J | 1 |
| Sheng, L | 1 |
| Gong, Y | 1 |
| Li, W | 1 |
| Ding, X | 1 |
| Wang, D | 2 |
| Liu, L | 1 |
| Peng, W | 1 |
| Liu, Z | 1 |
1 trial available for metoprolol and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2019 |
4 other studies available for metoprolol and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Metoprolol prevents neuronal dendrite remodeling in a canine model of chronic obstructive sleep apnea.
Topics: Animals; Chronic Disease; Dendrites; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; | 2020 |
Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria.
Topics: Adrenergic beta-1 Receptor Antagonists; AMP-Activated Protein Kinase Kinases; Animals; Atrial Fibril | 2017 |
Metoprolol Inhibits Profibrotic Remodeling of Epicardial Adipose Tissue in a Canine Model of Chronic Obstructive Sleep Apnea.
Topics: Adipokines; Adipose Tissue; Animals; Cardiomyopathies; Chronic Disease; Disease Models, Animal; Dogs | 2019 |
Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea.
Topics: Actins; Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-Associated De | 2015 |