metoprolol has been researched along with ST Elevated Myocardial Infarction in 18 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This meta-analysis aims to look at the impact of early intravenous Metoprolol in ST-segment elevation myocardial infarction (STEMI) before percutaneous coronary intervention (PCI) on infarct size, as measured by cardio magnetic resonance (CMR) and left ventricular ejection fraction." | 9.22 | Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials. ( Aiash, H; Chébl, P; Elgabrty, N; Elshenawy, S; Gaber, H; Motawea, KR; Reyad, SM; Rozan, SS; Shoib, S; Singh, RB; Swed, S; Talat, NE; Wahsh, EA, 2022) |
| "We assessed myocardial infarction in the transmural and lateral dimensions in a cohort of 220 acute ST-segment elevation myocardial infarction (STEMI) patients from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction)." | 5.41 | Coexistence of transmural and lateral wavefront progression of myocardial infarction in the human heart. ( Fernández-Friera, L; Fernández-Jiménez, R; Fuster, V; García-Álvarez, A; García-Ruiz, JM; Ibáñez, B; Jiménez-Blanco, M; Lobo-González, M; Lorca, R; Pizarro, G; Rossello, X, 2021) |
| "This meta-analysis aims to look at the impact of early intravenous Metoprolol in ST-segment elevation myocardial infarction (STEMI) before percutaneous coronary intervention (PCI) on infarct size, as measured by cardio magnetic resonance (CMR) and left ventricular ejection fraction." | 5.22 | Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials. ( Aiash, H; Chébl, P; Elgabrty, N; Elshenawy, S; Gaber, H; Motawea, KR; Reyad, SM; Rozan, SS; Shoib, S; Singh, RB; Swed, S; Talat, NE; Wahsh, EA, 2022) |
| "In patients with STEMI, who were being transported for primary PCI, early IV BB administration did not significantly affect ST-segment deviation after pPCI compared with placebo." | 2.94 | Beta-blocker effect on ST-segment: a prespecified analysis of the EARLY-BAMI randomised trial. ( Albarran, A; Alfonso, F; Botas, J; Dambrink, JH; de Smet, B; Fabris, E; Fernández-Avilés, F; Fuster, V; García-Lledó, A; Gosselink, M; Hermanides, R; Hernandez-Jaras, V; Ibanez, B; Kedhi, E; Kolkman, E; Lipsic, E; Mateos-Rodriguez, A; Nijveldt, R; Ottervanger, JP; Piek, JJ; Pizarro, G; Postma, S; Rasoul, S; Remkes, W; Roolvink, V; van 't Hof, AW; van Leeuwen, M; van Royen, N; Zamorano, J, 2020) |
| "In patients with anterior STEMI, early administration of intravenous metoprolol before primary PCI was associated with significantly fewer patients with severely depressed LV GCS and GLS, both at 1 week and 6 months." | 2.90 | Effect of Early Metoprolol During ST-Segment Elevation Myocardial Infarction on Left Ventricular Strain: Feature-Tracking Cardiovascular Magnetic Resonance Substudy From the METOCARD-CNIC Trial. ( Ajmone Marsan, N; Bax, JJ; Bucciarelli-Ducci, C; Delgado, V; Fernández-Jiménez, R; Fras, Z; Fuster, V; Ibáñez, B; Montero-Cabezas, JM; Pizarro, G; Podlesnikar, T; Sánchez-González, J, 2019) |
| "In a nonrestricted STEMI population, early intravenous metoprolol before PPCI was not associated with a reduction in infarct size." | 2.82 | Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention. ( Albarran, A; Alfonso, F; Alonso, J; Botas, J; Dambrink, JE; de Smet, B; Escalera, N; Fernández-Avilés, F; Fernández-Ortiz, A; Fuster, V; García-Lledó, A; Goicolea, J; Gosselink, M; Hernandez-Jaras, V; Ibáñez, B; Kedhi, E; Kolkman, E; Lipsic, E; Mateos, A; Navarro, F; Nijveldt, R; Ottervanger, JP; Piek, JJ; Pizarro, G; Postma, S; Rasoul, S; Remkes, W; Roolvink, V; van 't Hof, AWJ; van Leeuwen, M; van Royen, N; Zamorano, JL, 2016) |
| "In anterior STEMI patients undergoing primary angioplasty, the sooner IV metoprolol is administered in the course of infarction, the smaller the infarct and the higher the LVEF." | 2.82 | Impact of the Timing of Metoprolol Administration During STEMI on Infarct Size and Ventricular Function. ( Aguero, J; Cabrera, JA; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fuster, V; Galán-Arriola, C; García-Alvarez, A; García-Prieto, J; García-Ruiz, JM; Ibáñez, B; López-Martín, GJ; López-Melgar, B; Macías, A; Martínez-Tenorio, P; Mateos, A; Nuno-Ayala, M; Pérez-Asenjo, B; Pizarro, G; Sánchez-González, J, 2016) |
| "Metoprolol treatment reduced overall mortality (10% vs 26%, p = 0." | 1.56 | Metoprolol blunts the time-dependent progression of infarct size. ( Fuster, V; Galán-Arriola, C; García-Ruiz, JM; González-Del-Hoyo, M; Higuero-Verdejo, MI; Ibanez, B; Lobo-Gonzalez, M; López-Martín, GJ; Oliver, E; Pizarro, G; Rossello, X; Sánchez-González, J; Vilchez, JP, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 9 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motawea, KR | 1 |
| Gaber, H | 1 |
| Singh, RB | 1 |
| Swed, S | 1 |
| Elshenawy, S | 1 |
| Talat, NE | 1 |
| Elgabrty, N | 1 |
| Shoib, S | 1 |
| Wahsh, EA | 1 |
| Chébl, P | 1 |
| Reyad, SM | 1 |
| Rozan, SS | 1 |
| Aiash, H | 1 |
| Podlesnikar, T | 3 |
| Pizarro, G | 10 |
| Fernández-Jiménez, R | 7 |
| Montero-Cabezas, JM | 3 |
| Greif, N | 1 |
| Sánchez-González, J | 6 |
| Bucciarelli-Ducci, C | 3 |
| Marsan, NA | 1 |
| Fras, Z | 3 |
| Bax, JJ | 3 |
| Fuster, V | 10 |
| Ibáñez, B | 12 |
| Delgado, V | 3 |
| Lobo-Gonzalez, M | 3 |
| Galán-Arriola, C | 2 |
| Rossello, X | 3 |
| González-Del-Hoyo, M | 1 |
| Vilchez, JP | 1 |
| Higuero-Verdejo, MI | 1 |
| García-Ruiz, JM | 4 |
| López-Martín, GJ | 2 |
| Oliver, E | 1 |
| Ajmone Marsan, N | 2 |
| Lorca, R | 1 |
| Jiménez-Blanco, M | 1 |
| García-Álvarez, A | 2 |
| Fernández-Friera, L | 3 |
| Çınar, T | 1 |
| Karabağ, Y | 1 |
| Rencuzogullari, İ | 1 |
| Cağdaş, M | 1 |
| Fabris, E | 1 |
| Hermanides, R | 1 |
| Roolvink, V | 2 |
| Ottervanger, JP | 2 |
| van Royen, N | 2 |
| Mateos-Rodriguez, A | 1 |
| Dambrink, JH | 1 |
| Albarran, A | 2 |
| Fernández-Avilés, F | 2 |
| Botas, J | 2 |
| Remkes, W | 2 |
| Hernandez-Jaras, V | 2 |
| Kedhi, E | 2 |
| Zamorano, J | 1 |
| Alfonso, F | 2 |
| García-Lledó, A | 2 |
| van Leeuwen, M | 2 |
| Nijveldt, R | 2 |
| Postma, S | 2 |
| Kolkman, E | 2 |
| Gosselink, M | 2 |
| de Smet, B | 2 |
| Rasoul, S | 2 |
| Lipsic, E | 2 |
| Piek, JJ | 2 |
| van 't Hof, AW | 1 |
| Giannakopoulos, G | 1 |
| Noble, S | 1 |
| Díaz-Munoz, R | 1 |
| Valle-Caballero, MJ | 1 |
| García-Rubira, JC | 1 |
| Escalera, N | 3 |
| Akinjero, A | 1 |
| Donaldson, S | 1 |
| Simons, GR | 1 |
| Erlebacher, J | 1 |
| Bodi, V | 1 |
| Newby, LK | 1 |
| Mateos, A | 2 |
| Dambrink, JE | 1 |
| Fernández-Ortiz, A | 3 |
| Goicolea, J | 1 |
| Zamorano, JL | 1 |
| Navarro, F | 1 |
| Alonso, J | 1 |
| van 't Hof, AWJ | 1 |
| Nuno-Ayala, M | 1 |
| Aguero, J | 1 |
| García-Prieto, J | 1 |
| López-Melgar, B | 1 |
| Martínez-Tenorio, P | 1 |
| Macías, A | 2 |
| Pérez-Asenjo, B | 2 |
| Cabrera, JA | 1 |
| Hausenloy, DJ | 1 |
| Botker, HE | 1 |
| Engstrom, T | 1 |
| Erlinge, D | 1 |
| Heusch, G | 1 |
| Kloner, RA | 1 |
| Ovize, M | 1 |
| Yellon, DM | 1 |
| Garcia-Dorado, D | 1 |
| Sala-Vila, A | 1 |
| Calvo, C | 1 |
| Rodriguez, MD | 1 |
| Palazuelos, J | 1 |
| Ros, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The MEEffect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial[NCT01311700] | Phase 4 | 221 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518] | 250 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for metoprolol and ST Elevated Myocardial Infarction
| Article | Year |
|---|---|
Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials.
Topics: Humans; Metoprolol; Myocardial Infarction; Percutaneous Coronary Intervention; ST Elevation Myocardi | 2022 |
Should We Be Using Upstream Beta-Blocker Therapy for Acute Myocardial Infarction?
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Percutaneous Coronary Interv | 2021 |
Editor's Choice- Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome.
Topics: Acetylcysteine; Acute Disease; Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; | 2019 |
9 trials available for metoprolol and ST Elevated Myocardial Infarction
| Article | Year |
|---|---|
Left ventricular functional recovery of infarcted and remote myocardium after ST-segment elevation myocardial infarction (METOCARD-CNIC randomized clinical trial substudy).
Topics: Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Aged; Anterior Wall Myocardial | 2020 |
Five-Year Outcomes and Prognostic Value of Feature-Tracking Cardiovascular Magnetic Resonance in Patients Receiving Early Prereperfusion Metoprolol in Acute Myocardial Infarction.
Topics: Aged; Antihypertensive Agents; Drug Administration Schedule; Female; Humans; Magnetic Resonance Imag | 2020 |
Coexistence of transmural and lateral wavefront progression of myocardial infarction in the human heart.
Topics: Contrast Media; Gadolinium; Humans; Metoprolol; Myocardial Infarction; ST Elevation Myocardial Infar | 2021 |
Beta-blocker effect on ST-segment: a prespecified analysis of the EARLY-BAMI randomised trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Elect | 2020 |
Intravenous metoprolol during ongoing STEMI ameliorates markers of ischemic injury: a METOCARD-CNIC trial electrocardiographic study.
Topics: Animals; Electrocardiography; Humans; Metoprolol; Percutaneous Coronary Intervention; ST Elevation M | 2021 |
Effect of Early Metoprolol During ST-Segment Elevation Myocardial Infarction on Left Ventricular Strain: Feature-Tracking Cardiovascular Magnetic Resonance Substudy From the METOCARD-CNIC Trial.
Topics: Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Aged; Drug Administration Sched | 2019 |
Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Creatine Kinase; Double-Blind Method; Emergency M | 2016 |
Impact of the Timing of Metoprolol Administration During STEMI on Infarct Size and Ventricular Function.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Disease Models, Animal; Drug Administration Schedul | 2016 |
Nutritional preconditioning by marine omega-3 fatty acids in patients with ST-segment elevation myocardial infarction: A METOCARD-CNIC trial substudy.
Topics: Anti-Arrhythmia Agents; Arachidonic Acid; Diet; Eicosapentaenoic Acid; Female; Humans; Magnetic Reso | 2017 |
6 other studies available for metoprolol and ST Elevated Myocardial Infarction
| Article | Year |
|---|---|
Metoprolol blunts the time-dependent progression of infarct size.
Topics: Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Animals; Cardiac Imaging Techni | 2020 |
Microfistulas Causing Diverse Regional Ischemia: Consecutive Inferior and Lateral ST-Elevation Myocardial Infarction.
Topics: Aspirin; Coronary Angiography; Coronary Vessel Anomalies; Electrocardiography; Humans; Male; Metopro | 2020 |
76-Year-Old Man With Palpitations.
Topics: Adrenergic beta-Antagonists; Aged; Diagnosis, Differential; Electrocardiography; Humans; Male; Metop | 2017 |
Strain by Feature Tracking: A Short Summary of the Journey of CMR in STEMI.
Topics: Heart Ventricles; Humans; Magnetic Resonance Spectroscopy; Metoprolol; ST Elevation Myocardial Infar | 2019 |
Intravenous Beta-Blockers for Cardioprotection in STEMI: The Saga Continues.
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; ST Elevation Myocardial Infa | 2016 |
Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations.
Topics: Adenosine; Cardiotonic Agents; Clinical Trials as Topic; Combined Modality Therapy; Coronary Vessels | 2017 |