metoprolol has been researched along with Reperfusion Injury in 9 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 X 10(-4) mol/l, in comparison to that of metoprolol (10(-5) mol/l) and diltiazem (10(-7) mol/l), two widely used antiarrhythmic agents, on ischemia- and reperfusion-induced arrhythmias and heart functions, such as heart rate (HR), coronary flow (CF), aortic flow (AF), left ventricular developed pressure (LVDP), its first derivative (LVdp/dtmax), and left ventricular end-diastolic pressure (LVEDP) in isolated working rat hearts was examined." | 7.67 | Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. ( Braquet, P; Hosford, D; Koltai, M; Tosaki, A, 1989) |
| "2 X 10(-4) mol/l, in comparison to that of metoprolol (10(-5) mol/l) and diltiazem (10(-7) mol/l), two widely used antiarrhythmic agents, on ischemia- and reperfusion-induced arrhythmias and heart functions, such as heart rate (HR), coronary flow (CF), aortic flow (AF), left ventricular developed pressure (LVDP), its first derivative (LVdp/dtmax), and left ventricular end-diastolic pressure (LVEDP) in isolated working rat hearts was examined." | 3.67 | Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. ( Braquet, P; Hosford, D; Koltai, M; Tosaki, A, 1989) |
| "Metoprolol treatment was initiated in 27 patients (group 1), meanwhile 19 patients could not take metoprolol due to diverse contraindications (group 2)." | 2.72 | Coronary angioplasty induced oxidative stress and its relation with metoprolol use and plasma homocysteine levels. ( Ciçek, D; Cin, VG; Kara, AA; Pekdemir, H; Tamer, L; Yildirim, H; Yurtdaş, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Heusch, G | 1 |
| Kleinbongard, P | 1 |
| Hayashi, T | 1 |
| Saitou, Y | 1 |
| Nose, K | 1 |
| Nishioka, T | 1 |
| Ishii, T | 1 |
| Uemura, H | 1 |
| Kovacs, K | 1 |
| Hanto, K | 1 |
| Bognar, Z | 1 |
| Tapodi, A | 1 |
| Bognar, E | 1 |
| Kiss, GN | 1 |
| Szabo, A | 1 |
| Rappai, G | 1 |
| Kiss, T | 1 |
| Sumegi, B | 1 |
| Gallyas, F | 1 |
| Li, Q | 1 |
| Liu, Y | 1 |
| Jiao, J | 1 |
| Zhang, C | 1 |
| Lou, J | 1 |
| Ciçek, D | 1 |
| Tamer, L | 1 |
| Pekdemir, H | 1 |
| Cin, VG | 1 |
| Yildirim, H | 1 |
| Kara, AA | 1 |
| Yurtdaş, M | 1 |
| Módolo, NS | 1 |
| Castiglia, YM | 1 |
| Ganem, EM | 1 |
| Braz, JR | 1 |
| Vianna, PT | 1 |
| Vane, LA | 1 |
| Brand, T | 1 |
| Sharma, HS | 1 |
| Fleischmann, KE | 1 |
| Duncker, DJ | 1 |
| McFalls, EO | 1 |
| Verdouw, PD | 1 |
| Schaper, W | 1 |
| Liu, XK | 1 |
| Engelman, RM | 1 |
| Agrawal, HR | 1 |
| Das, DK | 1 |
| Koltai, M | 1 |
| Tosaki, A | 1 |
| Hosford, D | 1 |
| Braquet, P | 1 |
1 trial available for metoprolol and Reperfusion Injury
| Article | Year |
|---|---|
Coronary angioplasty induced oxidative stress and its relation with metoprolol use and plasma homocysteine levels.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Female; Homocysteine; Huma | 2006 |
8 other studies available for metoprolol and Reperfusion Injury
| Article | Year |
|---|---|
Is metoprolol more cardioprotective than other beta-blockers?
Topics: Adrenergic beta-Antagonists; Humans; Inflammation; Metoprolol; Reperfusion Injury | 2020 |
Efficacy of carvedilol for ischemia/reperfusion-induced oxidative renal injury in rats.
Topics: Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Creatinine; Kidney; Kidney Function Tests; | 2008 |
Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers.
Topics: Adrenergic beta-Antagonists; Animals; Benzimidazoles; Calcium Channel Blockers; Cardiotonic Agents; | 2009 |
Assessment of effects of IR and IPC on activities of cytochrome P450 isozymes in rats by a five-drug cocktail approach.
Topics: Animals; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactio | 2014 |
Acute renal ischemia model in dogs: effects of metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Dogs; Kidney; Kidney Tubular Necrosis, Acute; Metoprolol; Rena | 2001 |
Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion.
Topics: Animals; Blotting, Northern; Gene Expression; Genes, fos; Genes, jun; Genes, myc; Heart; Hemodynamic | 1992 |
Preservation of membrane phospholipids by propranolol, pindolol, and metoprolol: a novel mechanism of action of beta-blockers.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Fatty | 1991 |
Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion.
Topics: Animals; Arrhythmias, Cardiac; Diltiazem; Diterpenes; Ginkgolides; Heart Function Tests; Lactones; M | 1989 |