metoprolol has been researched along with Pregnancy in 100 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to evaluate the steady-state pharmacokinetics of metoprolol during pregnancy and lactation." | 9.22 | Pharmacokinetics of metoprolol during pregnancy and lactation. ( Caritis, SN; Easterling, TR; Eyal, S; Hankins, G; Hebert, MF; Honaker, MT; Kelly, EJ; Phillips, B; Risler, L; Rytting, E; Ryu, RJ; Shen, DD; Thummel, K; Venkataraman, R, 2016) |
| "To study the effects of isradipine or metoprolol on insulin sensitivity and lipid profiles as well as on blood pressure and umbilical vascular resistance in pre-eclamptic women in the third trimester of pregnancy." | 9.09 | Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia. ( Cacciatore, B; Kaaja, RJ; Laakso, M; Laivuori, HM; Tikkanen, MJ; Ylikorkala, RO, 1999) |
| "The plasma drug concentration-effect relationship after an oral dose of 100 mg metoprolol has been studied in 8 women in the third trimester of a pregnancy complicated by hypertension." | 9.07 | Plasma concentration-effect relationship of metoprolol during and after pregnancy. ( Högstedt, S; Rane, A, 1993) |
| "To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy." | 9.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy." | 9.05 | A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 8.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| "Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension." | 7.96 | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. ( Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F, 2020) |
| "Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth." | 7.67 | Pregnancy-induced increase in metoprolol metabolism. ( Högstedt, S; Lindberg, B; Peng, DR; Rane, A; Regårdh, CG, 1985) |
| "The disposition of oral metoprolol was studied in 5 women during the last trimester of pregnancy and 3 to 5 months after delivery." | 7.66 | Increased oral clearance of metoprolol in pregnancy. ( Högstedt, S; Lindberg, B; Rane, A, 1983) |
| "Metoprolol is a beta1-selective adrenoceptor blocking drug." | 6.36 | Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| " The oral bioavailability of metoprolol was lower (6-22%) during pregnancy than in non-pregnancy (9-49%)." | 5.28 | The rhesus monkey as a model for studies of pregnancy induced changes in metoprolol metabolism. ( Högstedt, S; Lindberg, BS; Moström, U; Rane, A; Regårdh, CG, 1990) |
| "To study the effects of isradipine or metoprolol on insulin sensitivity and lipid profiles as well as on blood pressure and umbilical vascular resistance in pre-eclamptic women in the third trimester of pregnancy." | 5.09 | Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia. ( Cacciatore, B; Kaaja, RJ; Laakso, M; Laivuori, HM; Tikkanen, MJ; Ylikorkala, RO, 1999) |
| "The plasma drug concentration-effect relationship after an oral dose of 100 mg metoprolol has been studied in 8 women in the third trimester of a pregnancy complicated by hypertension." | 5.07 | Plasma concentration-effect relationship of metoprolol during and after pregnancy. ( Högstedt, S; Rane, A, 1993) |
| "To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy." | 5.07 | Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994) |
| "Cord blood IgE levels and the development of allergy were studied in 29 children born by mothers who had been treated with the beta-adrenergic receptor blocking agent, metoprolol, during the pregnancy and in 23 children of placebo-treated mothers." | 5.06 | Intrauterine exposure to the beta-adrenergic receptor-blocking agent metoprolol and allergy. ( Björkstén, B; Finnström, O; Wichman, K, 1988) |
| "In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy." | 5.05 | A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 4.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| "Carvedilol administration during pregnancy was associated with neonatal hypoglycemia; however, it did not occur in a time- or dose-dependent manner." | 4.31 | α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age. ( Inai, K; Kubota, K; Shimada, E; Shinohara, T, 2023) |
| "Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension." | 3.96 | The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. ( Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F, 2020) |
| "Our findings suggest that neonates born to mothers exposed to β blockers in late pregnancy, including labetalol, are at elevated risk for neonatal hypoglycemia and bradycardia." | 3.83 | Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia. ( Bateman, BT; Desai, RJ; Fischer, MA; Hernandez-Diaz, S; Huybrechts, KF; Maeda, A; Mogun, H; Patorno, E; Seely, EW, 2016) |
| "The p-PBPK model predicted the PK changes of three model compounds (namely caffeine, metoprolol and midazolam) for CYP1A2, CYP2D6 and CYP3A4 during pregnancy within twofold of observed values." | 3.78 | A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4. ( Abduljalil, K; Gaohua, L; Jamei, M; Johnson, TN; Rostami-Hodjegan, A, 2012) |
| "The transfer of atenolol and metoprolol to human breast milk was studied in 7 lactating women with hypertension." | 3.67 | Atenolol and metoprolol. A comparison of their excretion into human breast milk. ( Kulas, J; Lunell, NO; Rane, A; Rosing, U; Stéen, B, 1984) |
| "Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth." | 3.67 | Pregnancy-induced increase in metoprolol metabolism. ( Högstedt, S; Lindberg, B; Peng, DR; Rane, A; Regårdh, CG, 1985) |
| "Seven women were treated with metoprolol 50-100 mg twice daily for hypertension in pregnancy." | 3.67 | Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol in maternal plasma, amniotic fluid and capillary blood of the neonate. ( Lindeberg, S; Lundborg, P; Regårdh, CG; Sandström, B, 1987) |
| "7 merino sheep in an advanced state of pregnancy received oxytocin for labour induction under the conditions of control, monotherapy with the beta 2-adrenergic tocolytic fenoterol, combination of the latter with the beta 1-blocking substance metoprolol (Beloc)." | 3.66 | [Effect of the combination of the beta-1-blocker metoprolol with the tocolytic fenoterol on uteroplacental hemodynamics and fetal cardiovascular sensitivity with particular consideration of intrauterine fetal malnutrition. Results of animal experiments]. ( Heimisch, W; Mendler, N; Schroll, A; Weidenbach, A; Wieshammer, E; Wischnik, A; Wischnik, B, 1982) |
| " Well-controlled GDM prolonged tmax for both enantiomers of metoprolol (1." | 2.80 | Influence of gestational diabetes on the stereoselective pharmacokinetics and placental distribution of metoprolol and its metabolites in parturients. ( Antunes, Nde J; Cavalli, RC; Lanchote, VL; Marques, MP; Moisés, EC, 2015) |
| "Seventeen patients in advanced premature labor (cervical dilatation greater than or equal to 3 cm and effacement greater than or equal to 50%) were randomized in a double-blind protocol to receive metoprolol (a beta 1-adrenergic antagonist) or a placebo in conjunction with intravenous and oral terbutaline (a beta 2-agonist) in an attempt to inhibit the side effects of terbutaline." | 2.65 | Intravenous terbutaline and simultaneous beta 1-blockade for advanced premature labor. ( Kitzmiller, JL; Nicolls, E; Ross, MG; Stubblefield, PG, 1983) |
| "The incidence of cardiac arrhythmias is estimated et 1." | 2.49 | [Electrical cardioversion in the treatment of cardiac arrhythmias during pregnancy--case report and review of literature]. ( Gałczyński, K; Kimber-Trojnar, Z; Kudlicki, J; Leszczyńska-Gorzelak, B; Marciniak, B; Oleszczukz, J, 2013) |
| "During evaluation for palpitations, presyncope, or syncope, seven pregnant women had documented ventricular tachycardia." | 2.38 | New-onset ventricular tachycardia during pregnancy. ( Allen, B; Brodsky, M; Doria, R; Sada, M; Sato, D; Thomas, G, 1992) |
| "Metoprolol is a beta1-selective adrenoceptor blocking drug." | 2.36 | Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "We found a five-fold increased risk of delivering a small-for-gestational-age infant in women with heart disease treated with a high dose of beta-blocker, and a two-fold increased risk among those treated with a low dose, showing an apparent dose-response relation." | 1.72 | Maternal beta-blocker dose and risk of small-for gestational-age in women with heart disease. ( Estensen, ME; Haualand, R; Langesaeter, E; Letting, AS; Sørbye, IK; Wiull, H, 2022) |
| "Recipients of severe twin-to-twin transfusion syndrome (TTTS) may suffer from low cardiac output caused by myocardial hypertrophy and sudden postnatal drop in preload." | 1.51 | Beta blocker therapy in recipients of twin-to-twin transfusion syndrome. ( Franz, AR; Gruendler, K; Lorenz, L; Poets, CF; Schwarz, CE, 2019) |
| "Physiologically based pharmacokinetic modeling is considered a valuable tool for predicting pharmacokinetic changes in pregnancy to subsequently guide in-vivo pharmacokinetic trials in pregnant women." | 1.48 | A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways. ( Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I, 2018) |
| "Supraventricular tachycardia is uncommon in pregnancy." | 1.40 | Management of labour and delivery in a woman with refractory supraventricular tachycardia. ( Dennis, AT; Gerstman, MD, 2014) |
| "Enalapril was continued for 42 days." | 1.38 | Therapeutic challenges and management of heart failure during pregnancy (part I). ( Bilińska, ZT; Czajkowski, K; Dangel, J; Demkow, M; Dzielińska, Z; Konka, M; Kryczka, K; Przybylski, A; Różański, J; Szczudlik, J, 2012) |
| "Women with persistent atrial fibrillation require anticoagulation and rate control, as well as fetal growth surveillance and antenatal testing." | 1.37 | Atrial fibrillation in pregnancy. ( Dahlke, LJ; DiCarlo-Meacham, LA, 2011) |
| "Takotsubo cardiomyopathy is a cardiac condition associated with the acute onset of chest pain, abnormalities in cardiac enzymes and electrocardiogram, and a distinct pattern of left ventricular dysfunction on echocardiography." | 1.35 | Takotsubo cardiomyopathy in pregnancy. ( Brezina, P; Isler, CM, 2008) |
| "Myocardial infarction is rare during pregnancy." | 1.31 | [Myocardial infarction, pregnancy and anesthesia]. ( Diar, N; Rezig, K; Walcker, JL, 2000) |
| "Metoprolol is a beta 1-adrenoreceptor antagonist which was previously shown to block the teratogenic effects of epinephrine and other catecholamines with beta 1-adrenoreceptor agonist properties." | 1.27 | Ventricular blood pressure and cardiac output changes in epinephrine- and metoprolol-treated chick embryos. ( Kolesari, GL; Kuhlmann, RS; Rajala, GM; Schnitzler, HJ, 1988) |
| "Arrhythmias were registered in 42 percent of the cases, in most cases during light anaesthesia before delivery." | 1.27 | [Effect of subpartal tocolysis on maternal cardiovascular parameters with subsequent cesarean section in general anesthesia]. ( Becker, J; Hartung, HJ; Pohl, R; Wiest, W, 1986) |
| " 17 patients (group I) got fenoterol-monotherapy; in 18 patients (group II) fenoterol was combined with the cardioselective beta-1-blocking agent metoprolol." | 1.26 | [Efficency of tocoylsis by fenoterol and fenoterol in combination with a beta-1-blocking compound (author's transl)]. ( Bernius, U; Hillemanns, HG; Irmer, M; Pohl, C; Steim, H; Trolp, R, 1980) |
| " In a dosage of 1." | 1.26 | [Investigations in animal experiments into the influence of the beta-1-selective blocking agent metoprolol on the cardiovascular and metabolic side effects of the tocolytic fenoterol]. ( Aschenbrenner, G; Birk, M; Blümel, G; Erhardt, W; Kohler, W; Pfeiffer, U; Sagerer, M; Strigl, R, 1981) |
| " After the establishment of these measurements Fenoterol has been given in an increasing dosage up to the upper therapeutical range." | 1.26 | [The cardiac hazard of tocolysis and antagonising possibilities. I. The haemodynamic situation of the patient during tocolysis/Protection of the myocardium by means of cardioselective beta-blockade. Experimental results (author's transl)]. ( Heimisch, W; Mendler, N; Schroll, A; Weidenbach, A; Wischnik, A, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (50.00) | 18.7374 |
| 1990's | 13 (13.00) | 18.2507 |
| 2000's | 5 (5.00) | 29.6817 |
| 2010's | 20 (20.00) | 24.3611 |
| 2020's | 12 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sørbye, IK | 1 |
| Haualand, R | 1 |
| Wiull, H | 1 |
| Letting, AS | 1 |
| Langesaeter, E | 1 |
| Estensen, ME | 1 |
| Allen, LB | 1 |
| Mirnics, K | 1 |
| Kubota, K | 1 |
| Inai, K | 1 |
| Shimada, E | 1 |
| Shinohara, T | 1 |
| van der Zande, JA | 1 |
| Cornette, JMJ | 1 |
| Roos-Hesselink, JW | 1 |
| Flint, RB | 1 |
| Heavner, MS | 1 |
| Cucci, MD | 1 |
| Barlow, B | 1 |
| Bell, CM | 1 |
| Eng, CC | 1 |
| Erdman, G | 1 |
| Li, M | 1 |
| Smith, SE | 1 |
| Aldhaeefi, M | 1 |
| Thompson Bastin, ML | 1 |
| Hawkins, WA | 1 |
| Rose, C | 1 |
| Lankford, A | 1 |
| de Ruiter, ML | 1 |
| Burghgraef, E | 1 |
| Peters, RHJ | 1 |
| Mulder, FEM | 1 |
| Kayser, A | 1 |
| Beck, E | 1 |
| Hoeltzenbein, M | 1 |
| Zinke, S | 1 |
| Meister, R | 1 |
| Weber-Schoendorfer, C | 1 |
| Schaefer, C | 1 |
| Vigneswaran, TV | 1 |
| Rosenthal, E | 1 |
| Bakalis, S | 1 |
| Nelson-Piercy, C | 1 |
| Chappell, L | 1 |
| Simpson, JM | 1 |
| Juusela, A | 1 |
| Nazir, M | 1 |
| Gimovsky, M | 1 |
| Ghafarzadeh, M | 1 |
| Shakarami, A | 1 |
| Yari, F | 1 |
| Namdari, P | 1 |
| Chuzi, S | 1 |
| Eucalitto, P | 1 |
| Yee, LM | 1 |
| Aurora, L | 1 |
| Nona, P | 1 |
| Ananthasubramaniam, K | 1 |
| Duan, L | 2 |
| Ng, A | 2 |
| Chen, W | 2 |
| Spencer, HT | 2 |
| Nguyen, J | 1 |
| Shen, AY | 1 |
| Lee, MS | 2 |
| Dallmann, A | 1 |
| Ince, I | 1 |
| Coboeken, K | 1 |
| Eissing, T | 1 |
| Hempel, G | 1 |
| Wilson, JL | 1 |
| Wilson, BH | 1 |
| Edwards, JR | 1 |
| Gruendler, K | 1 |
| Schwarz, CE | 1 |
| Lorenz, L | 1 |
| Poets, CF | 1 |
| Franz, AR | 1 |
| Gałczyński, K | 1 |
| Marciniak, B | 1 |
| Kudlicki, J | 1 |
| Kimber-Trojnar, Z | 1 |
| Leszczyńska-Gorzelak, B | 1 |
| Oleszczukz, J | 1 |
| Dennis, AT | 1 |
| Gerstman, MD | 1 |
| Antunes, Nde J | 2 |
| Cavalli, RC | 2 |
| Marques, MP | 2 |
| Moisés, EC | 1 |
| Lanchote, VL | 2 |
| Nizamuddin, SL | 1 |
| Broderick, DK | 1 |
| Minehart, RD | 1 |
| Kamdar, BB | 1 |
| Ryu, RJ | 1 |
| Eyal, S | 1 |
| Easterling, TR | 1 |
| Caritis, SN | 1 |
| Venkataraman, R | 1 |
| Hankins, G | 1 |
| Rytting, E | 1 |
| Thummel, K | 1 |
| Kelly, EJ | 1 |
| Risler, L | 1 |
| Phillips, B | 1 |
| Honaker, MT | 1 |
| Shen, DD | 1 |
| Hebert, MF | 1 |
| Bateman, BT | 1 |
| Patorno, E | 1 |
| Desai, RJ | 1 |
| Seely, EW | 1 |
| Mogun, H | 1 |
| Maeda, A | 1 |
| Fischer, MA | 1 |
| Hernandez-Diaz, S | 1 |
| Huybrechts, KF | 1 |
| Brezina, P | 1 |
| Isler, CM | 1 |
| Bernardon, M | 1 |
| Limone, A | 1 |
| Businelli, C | 1 |
| Maso, GP | 1 |
| Piccoli, M | 1 |
| Alberico, S | 1 |
| Cacciotti, L | 1 |
| Camastra, GS | 1 |
| Ansalone, G | 1 |
| DiCarlo-Meacham, LA | 1 |
| Dahlke, LJ | 1 |
| Esposito, F | 1 |
| Galfetti, M | 1 |
| Lava, SA | 1 |
| Balestra, B | 1 |
| Bianchetti, MG | 1 |
| Norrad, RS | 1 |
| Salehian, O | 1 |
| Kaya, T | 1 |
| Karadas, B | 1 |
| Altun, A | 1 |
| Sarac, İ | 1 |
| Bagcivan, I | 1 |
| Kryczka, K | 1 |
| Dzielińska, Z | 1 |
| Przybylski, A | 1 |
| Szczudlik, J | 1 |
| Dangel, J | 1 |
| Konka, M | 1 |
| Czajkowski, K | 1 |
| Różański, J | 1 |
| Bilińska, ZT | 1 |
| Demkow, M | 1 |
| Gaohua, L | 1 |
| Abduljalil, K | 1 |
| Jamei, M | 1 |
| Johnson, TN | 1 |
| Rostami-Hodjegan, A | 1 |
| Haas, DM | 1 |
| DʼAlton, M | 1 |
| Dugas, G | 1 |
| Fuller, J | 1 |
| Singh, S | 1 |
| Watson, J | 1 |
| Prochaczek, F | 1 |
| Winiarska, H | 1 |
| Gałecka, J | 1 |
| Weidinger, H | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Sandström, B | 10 |
| Lindeberg, S | 6 |
| Lundborg, P | 5 |
| Regårdh, CG | 7 |
| Werner, O | 1 |
| Kjellmer, I | 3 |
| Dagbjartsson, A | 3 |
| Hrbek, A | 1 |
| Karlsson, K | 2 |
| Rosén, KG | 4 |
| Finnström, O | 2 |
| Ezitis, J | 1 |
| Rydén, G | 2 |
| Wichman, K | 3 |
| Wischnik, A | 3 |
| Hötzinger, H | 1 |
| Wischnik, B | 2 |
| Schroll, A | 3 |
| Trenkwalder, U | 1 |
| Weidenbach, A | 3 |
| Siekmann, U | 1 |
| Heilmann, L | 1 |
| Brodde, OE | 1 |
| Di Renzo, GC | 1 |
| Venincasa, MD | 1 |
| Bleasdale, JE | 1 |
| Hammerle, AF | 1 |
| Ross, MG | 1 |
| Nicolls, E | 1 |
| Stubblefield, PG | 1 |
| Kitzmiller, JL | 1 |
| Karlberg, BE | 1 |
| Venuto, R | 1 |
| Burstein, P | 1 |
| Schneider, R | 1 |
| Kulas, J | 1 |
| Lunell, NO | 1 |
| Rosing, U | 1 |
| Stéen, B | 1 |
| Rane, A | 6 |
| Högstedt, S | 5 |
| Lindberg, B | 2 |
| Heimisch, W | 2 |
| Mendler, N | 2 |
| Wieshammer, E | 1 |
| Strigl, R | 2 |
| Pfeiffer, U | 2 |
| Sagerer, M | 1 |
| Birk, M | 1 |
| Aschenbrenner, G | 2 |
| Erhardt, W | 1 |
| Kohler, W | 1 |
| Blümel, G | 2 |
| Steyer, M | 1 |
| Poleska, W | 1 |
| Diemer, HP | 1 |
| Schmidt, H | 1 |
| Heidenreich, J | 1 |
| Liedholm, H | 1 |
| Melander, A | 1 |
| Bitzén, PO | 1 |
| Helm, G | 1 |
| Lönnerholm, G | 1 |
| Mattiasson, I | 1 |
| Nilsson, B | 1 |
| Wåhlin-Boll, E | 1 |
| Agren, G | 1 |
| Ervik, M | 1 |
| Trolp, R | 2 |
| Irmer, M | 2 |
| Bernius, U | 1 |
| Pohl, C | 1 |
| Steim, H | 1 |
| Hillemanns, HG | 1 |
| Frigo, P | 1 |
| Eppel, W | 1 |
| Frank, A | 1 |
| Ulm, M | 1 |
| Golaszewski, T | 1 |
| Gruber, W | 1 |
| Jannet, D | 1 |
| Carbonne, B | 1 |
| Sebban, E | 1 |
| Milliez, J | 1 |
| Schreiner, MS | 1 |
| Laivuori, HM | 1 |
| Laakso, M | 1 |
| Tikkanen, MJ | 1 |
| Cacciatore, B | 1 |
| Ylikorkala, RO | 1 |
| Kaaja, RJ | 1 |
| Jahn, GA | 1 |
| Kalia, V | 1 |
| Hole, D | 1 |
| Wilson, CA | 1 |
| Deis, RP | 1 |
| Rezig, K | 1 |
| Diar, N | 1 |
| Walcker, JL | 1 |
| Brogden, RN | 2 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Greed, R | 1 |
| Van Petten, GR | 1 |
| Brodsky, M | 1 |
| Doria, R | 1 |
| Allen, B | 1 |
| Sato, D | 1 |
| Thomas, G | 1 |
| Sada, M | 1 |
| Shen, JJ | 1 |
| Wanwimolruk, S | 1 |
| Mills, RG | 1 |
| Roberts, MS | 1 |
| Ziccone, SP | 1 |
| Paull, JD | 1 |
| Tai, YT | 1 |
| Lo, CW | 1 |
| Chow, WH | 1 |
| Cheng, CH | 1 |
| Rath, W | 1 |
| Schrader, J | 1 |
| Guhlke, U | 1 |
| Buhr-Schinner, H | 1 |
| Haupt, A | 1 |
| Kramer, A | 1 |
| Kuhn, W | 1 |
| Lindberg, BS | 2 |
| Moström, U | 1 |
| Resch, BA | 1 |
| Molnár, GB | 2 |
| Papp, G | 2 |
| Lechner, W | 1 |
| Artner-Dworzak, E | 1 |
| Heim, K | 1 |
| Marth, C | 1 |
| Puschendorf, B | 1 |
| Björkstén, B | 1 |
| Henriksson, BA | 1 |
| Biber, B | 1 |
| Häggendal, J | 1 |
| Lundberg, D | 1 |
| Pontén, J | 1 |
| Kawecka-Jaszcz, K | 1 |
| Skoczeń, M | 1 |
| Viinikka, L | 1 |
| Ylikorkala, O | 1 |
| Benfield, P | 1 |
| Clissold, SP | 1 |
| Holm, B | 1 |
| Rajala, GM | 1 |
| Kolesari, GL | 1 |
| Kuhlmann, RS | 1 |
| Schnitzler, HJ | 1 |
| Resch, B | 1 |
| Kertész, E | 1 |
| Csanády, M | 1 |
| Popitz-Bergez, F | 1 |
| Datta, S | 1 |
| Ostheimer, GW | 1 |
| Olofsson, P | 1 |
| Montan, S | 1 |
| Sartor, G | 1 |
| Sjöberg, NO | 1 |
| Suonio, S | 1 |
| Saarikoski, S | 1 |
| Tahvanainen, K | 1 |
| Pääkkönen, A | 1 |
| Olkkonen, H | 1 |
| Pohl, R | 1 |
| Wiest, W | 1 |
| Hartung, HJ | 1 |
| Becker, J | 1 |
| Axelsson, O | 1 |
| Lindmark, G | 1 |
| Peng, DR | 1 |
7 reviews available for metoprolol and Pregnancy
| Article | Year |
|---|---|
Caring for two in the ICU: Pharmacologic management of pregnancy-related complications.
Topics: Female; Humans; Intensive Care Units; Metoprolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, | 2023 |
[Electrical cardioversion in the treatment of cardiac arrhythmias during pregnancy--case report and review of literature].
Topics: Adult; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Digoxin; Electric Countershock; | 2013 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris.
Topics: Angina Pectoris; Animals; Blood Glucose; Dogs; Drug Interactions; Female; Hemodynamics; Humans; Hype | 1977 |
New-onset ventricular tachycardia during pregnancy.
Topics: Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follo | 1992 |
[Beta-blockaders in the treatment of hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Ox | 1985 |
Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders.
Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Cardiomegaly; Coronary Disease; Drug Interactions; D | 1986 |
11 trials available for metoprolol and Pregnancy
| Article | Year |
|---|---|
Influence of gestational diabetes on the stereoselective pharmacokinetics and placental distribution of metoprolol and its metabolites in parturients.
Topics: Adult; Antihypertensive Agents; Diabetes, Gestational; Female; Fetal Blood; Humans; Hypertension; In | 2015 |
Pharmacokinetics of metoprolol during pregnancy and lactation.
Topics: Adrenergic beta-Antagonists; Adult; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Female; Ge | 2016 |
Neonatal effects of beta-blocking drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Apgar Score; Birth Weight; Carbon Dioxide; Cephalometry; Clinical Trial | 1984 |
Intravenous terbutaline and simultaneous beta 1-blockade for advanced premature labor.
Topics: Administration, Oral; Adult; Birth Weight; Blood Pressure; Clinical Trials as Topic; Double-Blind Me | 1983 |
A placebo controlled trial of metoprolol in the treatment of hypertension in pregnancy.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Embryonic and Fetal Development; Female; Human | 1984 |
Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial.
Topics: Adult; Birth Weight; Blood Pressure; Cesarean Section; Drug Administration Schedule; Female; Humans; | 1994 |
Plasma concentration-effect relationship of metoprolol during and after pregnancy.
Topics: Adult; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Metoprolol; Ph | 1993 |
Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; F | 1999 |
Intrauterine exposure to the beta-adrenergic receptor-blocking agent metoprolol and allergy.
Topics: Double-Blind Method; Female; Fetal Blood; Follow-Up Studies; Humans; Hypersensitivity; Immunoglobuli | 1988 |
Effects of beta 1-adrenoceptor blockade in the treatment of hypertension during pregnancy in diabetic women.
Topics: Adult; Atenolol; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertensi | 1986 |
A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy.
Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fetus; Gestational Age; Humans; | 1985 |
82 other studies available for metoprolol and Pregnancy
| Article | Year |
|---|---|
Maternal beta-blocker dose and risk of small-for gestational-age in women with heart disease.
Topics: Female; Fetal Development; Fetal Growth Retardation; Heart Diseases; Humans; Infant; Infant, Newborn | 2022 |
Metoprolol Inhibits Developmental Brain Sterol Biosynthesis in Mice.
Topics: Animals; Brain; Cholesterol; Chromatography, Liquid; Female; Metoprolol; Mice; Nebivolol; Oxidoreduc | 2022 |
α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age.
Topics: Adrenergic beta-Antagonists; Carvedilol; Female; Gestational Age; Humans; Hypoglycemia; Infant, Newb | 2023 |
Maternal, fetal, neonatal and breastmilk flecainide concentration during maternal therapy and lactation: a case report.
Topics: Adult; Breast Feeding; Female; Flecainide; Humans; Infant; Infant, Newborn; Lactation; Metoprolol; M | 2023 |
[A pregnant woman with de novo atrial fibrillation].
Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Female; Heart Atria; Humans; Metoprolol | 2023 |
Neonatal effects of intrauterine metoprolol/bisoprolol exposure during the second and third trimester: a cohort study with two comparison groups.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Birth Weight; Bisoprolol; Cohort Studies; Fema | 2020 |
Transplacental metoprolol for fetal supraventricular tachycardia.
Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Infant, Newborn; Metoprolol; Pregna | 2020 |
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi | 2020 |
The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Incidence; | 2020 |
A Pregnant Woman With Shortness of Breath.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Anticoagulants; Cesarean Section; Dyspnea; Echocardio | 2021 |
A Pregnant Patient with Elevated Heart Rate.
Topics: Anti-Arrhythmia Agents; Female; Fluid Therapy; Heart Rate; Humans; Metoprolol; Pregnancy; Pregnancy | 2021 |
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi | 2017 |
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metroni | 2018 |
13 weeks' gestation · heart palpitations · chest tightness · Dx?
Topics: Adult; Anti-Arrhythmia Agents; Female; Gestational Age; Humans; Metoprolol; Muscle Tonus; Myocardium | 2018 |
Beta-blocker subtypes and risk of low birth weight in newborns.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Birth Weight; California; Fem | 2018 |
Beta blocker therapy in recipients of twin-to-twin transfusion syndrome.
Topics: Adrenergic beta-1 Receptor Antagonists; Cardiac Output, Low; Echocardiography; Female; Fetofetal Tra | 2019 |
Management of labour and delivery in a woman with refractory supraventricular tachycardia.
Topics: Adult; Amides; Amnion; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Epidural; Anes | 2014 |
Spontaneous coronary artery dissection in a parturient with Nail-Patella syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antidiuretic | 2015 |
Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia.
Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Cohort Studies; Female; Humans; Hypertension; Hy | 2016 |
Takotsubo cardiomyopathy in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Echocardiography; Electrocardiography; Female; Humans; Metoprolo | 2008 |
Acute myocardial infarction in pregnancy.
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Apgar Score; Aspirin; Cesarean Section; Coron | 2008 |
Atrial fibrillation in a pregnant woman with a normal heart.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Cesarean Section; Electrocardiography; Female; H | 2010 |
Atrial fibrillation in pregnancy.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Electrocardiography; Female; Hum | 2011 |
Fetopathy probably associated to self-medication with a blocker of the renin-angiotensin system.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Antimalarials; Cesarean | 2011 |
Management of severe mitral stenosis during pregnancy.
Topics: Adult; Anticoagulants; Catheterization; Dalteparin; Drug Therapy, Combination; Echocardiography, Dop | 2011 |
Effects and selectivity of CL 316243, beta-3-adrenoceptor agonist, in term-pregnant rat myometrium.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Cyclic GMP; Dioxoles; Female; Gestational Age; In Vit | 2012 |
Therapeutic challenges and management of heart failure during pregnancy (part I).
Topics: Adult; Digitalis; Drug Therapy, Combination; Enalapril; Female; Furosemide; Heart Failure; Humans; M | 2012 |
A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4.
Topics: Adult; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Drug Desi | 2012 |
Pharmacogenetics and other reasons why drugs can fail in pregnancy: higher dose or different drug?
Topics: Antihypertensive Agents; Chronic Disease; Cytochrome P-450 CYP2D6; Drug Substitution; Female; Humans | 2012 |
Stereoselective determination of metoprolol and its metabolite α-hydroxymetoprolol in plasma by LC-MS/MS: application to pharmacokinetics during pregnancy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Chromatography, High Pressure Liquid; Female; Humans; | 2013 |
Pheochromocytoma and pregnancy: a case report and review of anesthetic management.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; A | 2004 |
[Termination of atrio-ventricular reentrant tachycardia in a pregnant woman using transoesophageal atrial pacing and pharmacotherapy].
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Female; Humans; Metoprolol; Pregnancy; Pr | 2008 |
[Tocolysis, a therapeutic measure requiring caution].
Topics: Adrenergic beta-Agonists; Energy Metabolism; Female; Heart; Humans; Magnesium; Metoprolol; Obstetric | 1980 |
Adrenergic beta-receptor blockers in hypertension of pregnancy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Birth Weight; Blood Pressure; Delivery, Obstetric; F | 1982 |
Disposition of the adrenergic blocker metoprolol in the late pregnant women, the amniotic fluid, the cord blood and the neonate.
Topics: Adrenergic beta-Antagonists; Amniotic Fluid; Female; Fetal Blood; Humans; Hypertension; Infant, Newb | 1983 |
Some notes on the hormonal and haemodynamic responses to stressful stimuli.
Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Anesthesia, Epidural; Anesthesia, General; | 1984 |
Clinical trials of adrenergic antagonists in pregnancy hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growt | 1984 |
Maternal beta-adrenoceptor blockade reduces fetal tolerance to asphyxia. A study in pregnant sheep.
Topics: Adrenergic beta-Antagonists; Animals; Cardiac Output; Catecholamines; Cerebrovascular Circulation; E | 1984 |
[The effect of the beta 1-blocker metoprolol on cyclic 3',5'-adenosine monophosphate in various tissues during long-term tocolysis with fenoterol. Animal experiments on the question of the interactive effects of the principal and adverse effects of beta 2
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Drug Therapy, Combination; Female; Fenoterol; Fetus; | 1984 |
[Maternal and fetal hemodynamics under simultaneous beta stimulation and beta1 blockade in a tocolysis model. Considerations on status of the neonatal beta receptor and transplacental passage of metoprolol].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Cyclic AMP; Female; Fetal Blood; Fetus | 1984 |
The identification and characterization of beta-adrenergic receptors in human amnion tissue.
Topics: Amnion; Binding, Competitive; Cyclic AMP; Ethanolamines; Female; Humans; Iodocyanopindolol; Isoprote | 1984 |
[New aspects in the therapy of pregnancy-induced hypertension].
Topics: Anesthesia, Epidural; Epoprostenol; Female; Fenoterol; Humans; Hypertension; Labetalol; Metoprolol; | 1983 |
Pheochromocytoma: antepartum diagnosis and management with tumor resection in the puerperium.
Topics: Adrenal Gland Neoplasms; Adult; Combined Modality Therapy; Female; Humans; Metoprolol; Pheochromocyt | 1984 |
Disposition of the adrenergic blocker metoprolol in the late-pregnant woman, the amniotic fluid, the cord blood and the neonate.
Topics: Amniotic Fluid; Drug Therapy, Combination; Female; Fetal Blood; Humans; Hydralazine; Hypertension; I | 1984 |
Atenolol and metoprolol. A comparison of their excretion into human breast milk.
Topics: Atenolol; Female; Fetal Blood; Humans; Hypertension; Metoprolol; Milk, Human; Pregnancy; Pregnancy C | 1984 |
Increased oral clearance of metoprolol in pregnancy.
Topics: Administration, Oral; Adult; Female; Humans; Liver; Metoprolol; Pregnancy; Propanolamines; Protein B | 1983 |
[Effect of the combination of the beta-1-blocker metoprolol with the tocolytic fenoterol on uteroplacental hemodynamics and fetal cardiovascular sensitivity with particular consideration of intrauterine fetal malnutrition. Results of animal experiments].
Topics: Animals; Ethanolamines; Female; Fenoterol; Fetus; Hemodynamics; Metoprolol; Oxytocin; Placenta; Plac | 1982 |
[The cardiac hazard of tocolysis and antagonising possibilities. I. The haemodynamic situation of the patient during tocolysis/Protection of the myocardium by means of cardioselective beta-blockade. Experimental results (author's transl)].
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Vessels; Dogs; Ethanolamines; Female; Fenoterol; H | 1982 |
[Investigations in animal experiments into the influence of the beta-1-selective blocking agent metoprolol on the cardiovascular and metabolic side effects of the tocolytic fenoterol].
Topics: Animals; Blood Pressure; Dogs; Drug Interactions; Ethanolamines; Female; Fenoterol; Heart; Heart Rat | 1981 |
Combined use of beta-sympathomimetic drugs and beta-blockers during labour.
Topics: Atenolol; Blood Pressure; Ethanolamines; Female; Fenoterol; Heart Rate; Humans; Metoprolol; Obstetri | 1981 |
Accumulation of atenolol and metoprolol in human breast milk.
Topics: Atenolol; Female; Humans; Kinetics; Lactation; Metoprolol; Milk, Human; Pregnancy; Propanolamines | 1981 |
Disposition of metoprolol in the newborn.
Topics: Female; Humans; Hypertension; Infant, Newborn; Maternal-Fetal Exchange; Metoprolol; Pregnancy; Pregn | 1981 |
Metoprolol excretion into breast milk.
Topics: Female; Half-Life; Humans; Metoprolol; Milk, Human; Pregnancy; Propanolamines; Time Factors | 1980 |
[Tocolysis with a beta-receptor stimulating compound in patients with WPW-syndrome. A casuistic report (author's transl)].
Topics: Adult; Ethanolamines; Female; Fenoterol; Humans; Metoprolol; Obstetric Labor, Premature; Pregnancy; | 1980 |
[Efficency of tocoylsis by fenoterol and fenoterol in combination with a beta-1-blocking compound (author's transl)].
Topics: Drug Therapy, Combination; Ethanolamines; Female; Fenoterol; Heart Rate; Humans; Metoprolol; Obstetr | 1980 |
Management of supraventricular tachycardia during hexoprenaline therapy for preterm labour: benefit of cardioselective beta blockade?
Topics: Adult; Female; Hexoprenaline; Humans; Metoprolol; Obstetric Labor, Premature; Pregnancy; Tachycardia | 1995 |
Safety and effectiveness data: will children gain access?
Topics: Adrenergic beta-Antagonists; Child; Female; Heart Failure; Humans; Metoprolol; Pregnancy; Safety; Tr | 1998 |
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergi | 1999 |
[Myocardial infarction, pregnancy and anesthesia].
Topics: Adrenergic beta-Antagonists; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesic | 2000 |
Drugs in current use: metoprolol.
Topics: Adult; Aged; Angina Pectoris; Child; Female; Humans; Hypertension; Metoprolol; Pregnancy; Propanolam | 1979 |
Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy.
Topics: Apgar Score; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Growth Retardation; Fetus; Hu | 1978 |
Cardiovascular effects of metoprolol in the pregnant ewe and fetus.
Topics: Animals; Female; Fetus; Heart Rate; Hemodynamics; Isoproterenol; Metoprolol; Pregnancy; Pregnancy, A | 1976 |
Response to beta-blockers in maternal and fetal rat hearts in vitro.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Female; Heart; Heart Rate; Isoproterenol; Labetalol; | 1991 |
The actions of tulobuterol on isolated preparations of gravid human myometrium.
Topics: Adrenergic beta-Agonists; Electric Stimulation; Epinephrine; Female; Humans; In Vitro Techniques; Is | 1990 |
Successful resuscitation and survival following massive overdose of metoprolol.
Topics: Adult; Drug Overdose; Female; Glucagon; Heart Arrest; Humans; Metoprolol; Pregnancy; Pregnancy Compl | 1990 |
[24-hour blood pressure measurement in normal pregnancy in hypertensive pregnant patients].
Topics: Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Dihydralazine; Female; Humans; Infusion P | 1990 |
The rhesus monkey as a model for studies of pregnancy induced changes in metoprolol metabolism.
Topics: Administration, Oral; Animals; Female; Injections, Intravenous; Macaca; Macaca mulatta; Metabolic Cl | 1990 |
Betaloc therapy in pregnancy-associated mild and moderately severe hypertension.
Topics: Adolescent; Adult; Blood Pressure; Female; Heart Rate; Heart Rate, Fetal; Humans; Hypertension; Infa | 1990 |
Determination of light-chain myosin in pregnancy and under tocolysis.
Topics: Coronary Disease; Female; Hexoprenaline; Humans; Immunoenzyme Techniques; Metoprolol; Myosins; Pregn | 1989 |
Acute blockade of beta 1-receptors in the asphyxiated sheep fetus.
Topics: Animals; Female; Fetal Hypoxia; Hemodynamics; Metoprolol; Pregnancy; Receptors, Adrenergic, beta; Sh | 1987 |
Cardiovascular effects of enflurane and asphyxia during long-term beta 1-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Animals; Asphyxia; Cardiovascular Diseases; Drug I | 1985 |
Beta blockers inhibit fetal thromboxane A2 production in vitro.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Platelets; Female; Fetal Blood; Humans; Infant, Newborn | 1988 |
The effect of hydralazine on steady-state plasma concentrations of metoprolol in pregnant hypertensive women.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Meto | 1988 |
Ventricular blood pressure and cardiac output changes in epinephrine- and metoprolol-treated chick embryos.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Chick Embryo; Epinephrine; Female; Fe | 1988 |
Control and long-term inhibition of foetal supraventricular tachyarrhythmia with a cardioselective beta-receptor blocker administered to the mother.
Topics: Adult; Female; Fetal Diseases; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; Metoprolol; | 1988 |
Intravascular epinephrine may not increase heart rate in patients receiving metoprolol.
Topics: Epinephrine; Female; Heart Rate; Humans; Metoprolol; Pregnancy; Pregnancy Complications, Cardiovascu | 1988 |
Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol in maternal plasma, amniotic fluid and capillary blood of the neonate.
Topics: Amniotic Fluid; Capillaries; Female; Half-Life; Humans; Hypertension; Infant, Newborn; Male; Metopro | 1987 |
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chorionic Villi; Dihydralazine; Female; Furosem | 1986 |
[Effect of subpartal tocolysis on maternal cardiovascular parameters with subsequent cesarean section in general anesthesia].
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Arrhythmias, Cardiac; Blood Pressure; Cesarean | 1986 |
Influence of the beta-1 selective blocker, metoprolol, on the development of pulmonary edema in tocolytic therapy.
Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Dogs; Female; Fenoterol; Heart Rate | 1986 |
Pregnancy-induced increase in metoprolol metabolism.
Topics: Adult; Blood Proteins; Female; Humans; Hypertension; Kinetics; Metoprolol; Pregnancy; Pregnancy Comp | 1985 |
Maternal treatment with a cardioselective beta-blocking agent--consequences for the ovine fetus during intermittent asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Glucose; Cardiovascular System; Electrocardiog | 1985 |